Month: December 2020

Promoting the research and development of drug for cataract and reducing the blindness rate of cataract

Author: Wang Yandong DOI: 10.3760/cma.j.cn115989-20201102-00726 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1001-1003. Abstract                              [View PDF] [Read Full Text] With the aging of the population and changes of people’s lifestyle, age-related eye disease, metabolic-related eye disease and fundus lesions […]

Preparation and drug release effect evaluation of drug-loaded cross-linked decellularized corneal stromal lenticules in vitro

Authors: Rao Jing,  Chen Jiansu,  Gu Jianing,  Chen Xiao,  Wang Yini,  Liu Yonghuan,  Pu Aijun,  Zhou Qizhi DOI: 10.3760/cma.j.cn115989-20190817-00353 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1004-1010. Abstract                               [View PDF] [Read Full Text] Objective To prepare a drug release system of drug-loaded cross-linked […]

Network pharmacology analysis of metformin against diabetic retinopathy

Authors: Chen Yuan,  Xing Qian,  Huang Zhengru DOI: 10.3760/cma.j.cn115989-20191215-00543 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1011-1015. Abstract                               [View PDF] [Read Full Text] Objective To explore the pharmacological molecular mechanisms of metformin against diabetic retinopathy (DR) based on network pharmacology approach. Methods After […]

Anti-apoptosis and anti-inflammation effects and mechanism of berberine on high-concentration glucose induced rat retinal Müller cells

Authors: Jin Yiping,  Zhu Haohao,  Liao Yujie,  Yu Xiaoyan DOI: 10.3760/cma.j.cn115989-20200917-00647 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1016-1024. Abstract                               [View PDF] [Read Full Text] Objective To investigate the effects of berberine on Sprague Dawley (SD) rat retinal Müller cells cultured by high […]

Protective effect and mechanism of esculetin on oxidative damaged ARPE-19 cells

Authors: Zhang Yingjun,  Bai Ge,  He Xiangdong,  Zhang Donglei,  He Wei DOI: 10.3760/cma.j.cn115989-20200224-00101 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1025-1031. Abstract                               [View PDF] [Read Full Text] Objective To study the protective effect and the mechanism of esculetin on oxidative-stressed human retinal pigment […]

Ocular pharmacokinetics of econazole solid lipid nanoparticle eye drops after single dose topical administration in rabbits

Authors: Liang Zhen,  Zhang Zhen,  Li Jingguo,  Yang Jingjing,  Lu Ping,  Zhou Tianyang,  Zhang Junjie DOI: 10.3760/cma.j.cn115989-20191008-00429 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1032-1037. Abstract                               [View PDF] [Read Full Text] Objective To investigate the pharmacokinetics of econazole solid lipid nanoparticles (E-SLNs) after […]

Ocular pharmacokinetics of topical administration of butenafine nanomicelles in rabbit eyes

Authors: Lu Ping,  Liang Zhen,  Zhang Zhen,  Yang Jingjing,  Song Fei,  Li Jingguo,  Zhou Tianyang,  Zhang Junjie DOI: 10.3760/cma.j.cn115989-20200526-00374 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1038-1044. Abstract                               [View PDF] [Read Full Text] Objective To study the pharmacokinetics of the broad-spectrum antifungal drug […]

Influence of benzalkonium chloride in anti-glaucoma medications on intraocular pressure and ocular surface: a Meta-analysis

Authors: Liu Liling,  Wu Kaili,  Yu Minbin DOI: 10.3760/cma.j.cn115989-20200917-00650 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1045-1051. Abstract                               [View PDF] [Read Full Text] Objective To evaluate the influence of benzalkonium chloride (BAK) in anti-glaucoma medication on intraocular pressure and ocular surface. Methods A […]

Effects of recombinant human epidermal growth factor on epithelial recovery and tear film stability after enhanced transepithelial corneal crosslinking

Authors: Lin Zhirong,  Wu Huping,  Luo Shunrong,  Xie Zhiwen,  Fang Xie,  Xiao Xianwen,  Yan Lei,  Dong Nuo,  Shang Xumin,  Liu Zhaosheng DOI: 10.3760/cma.j.cn115989-20200917-00651 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1052-1059. Abstract                              [View PDF] [Read Full Text] Objective To […]

A randomized controlled clinical study on amniotic stent and silicone tube implantation through nasolacrimal duct for the treatment of lacrimal duct obstruction disease

Authors: Cui Hua,  Xiao Fan,  Lai Pinghong,  He Yalin,  Zhou Min,  Zhao Jialiang DOI: 10.3760/cma.j.cn115989-20190610-00253 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1061-1065. Abstract                              [View PDF] [Read Full Text] Objective To investigate the efficacy and side effects of amnion stent implanted in lacrimal […]