Category: Yearwise

Research progress of FYCO1 gene mutation

Authors:He Chenhao,  Li Yuying,  Zhong Zilin,  Chen Jianjun DOI: 10.3760/cma.j.issn.2095-0160.2019.09.014 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 755-758. Abstract FYVE and coiled-coil domain containing 1(FYCO1) is an adaptor of cellular autophagy which has RUN domain, coiled coil domain, FYVE domain, GOLD domain and LIR domain.FYCO1 protein is widely expressed and mainly interacts with Atg8 […]

Research progress of Cre/LoxP system in the eyes of animal model

Authors:Lou Xiangfeng,  Luo Xue,  Shen Yin DOI: 10.3760/cma.j.issn.2095-0160.2019.09.015 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 759-763. Abstract Cre/LoxP system has been widely used as new type of gene targeting, which can transform genes in specific tissues and organs, remove specific gene fragments, and help to study the effects of specific genes on growth and […]