Authors: Ma Xiaochen, Liu Hongling DOI: 10.3760/cma.j.cn115989-20190930-00425 Published 2022-10-10 Cite asChin J Exp Ophthalmol, 2022, 40(10): 972-975. Abstract [View PDF] [Read Full Text] The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated endonuclease 9 (Cas9) technology is a gene editing technology that uses […]
Category: Review
Progress in the research on clinical features of Bestrophinopathies and mutations in BEST1 gene
Authors: Yang Shangying, Sheng Xunlun DOI: 10.3760/cma.j.cn115989-20200921-00659 Published 2022-10-10 Cite asChin J Exp Ophthalmol, 2022, 40(10): 976-980. Abstract [View PDF] [Read Full Text] Bestrophinopathies are a group of inherited macular dystrophies caused by BEST1 gene mutations including Best vitelliform macular dystrophy, adult-onset […]
Epigenetic regulation and retinal degenerative diseases
Authors: Zhang Hua, Pang Jijing DOI: 10.3760/cma.j.cn115989-20191015-00442 Published 2022-10-10 Cite asChin J Exp Ophthalmol, 2022, 40(10): 981-985. Abstract [View PDF] [Read Full Text] Epigenetics pertains to heritable alterations in gene expression when the nucleotide sequence remains unchanged.Epigenetic regulation […]
Role of microRNA-21 in the occurrence and development of ophthalmic diseases
Authors: Sun Jijun, Ruan Qingguo, Shi Weiyun DOI: 10.3760/cma.j.cn115989-20191007-00428 Published 2022-10-10 Cite asChin J Exp Ophthalmol, 2022, 40(10): 986-991. Abstract [View PDF] [Read Full Text] MicroRNA (miRNA) is a short noncoding RNA, which can regulate gene expression.miR-21 is one of the human miRNAs […]
Research progress on regulation of lncRNA in age-related ophthalmopathy
Authors: Cheng Tianyu, Guan Huaijin DOI: 10.3760/cma.j.cn115989-20190125-00035 Published 2022-10-10 Cite asChin J Exp Ophthalmol, 2022, 40(10): 992-995. Abstract [View PDF] [Read Full Text] Long non-coding RNA (lncRNA) is a class of transcripts longer than 200 nucleotides, which do not […]
Advances in rodent models of retinal neovascularization
Authors: Xu Qianhui, Chen Jun, Shao Yi DOI: 10.3760/cma.j.cn115989-20200211-00064 Published 2022-10-10 Cite asChin J Exp Ophthalmol, 2022, 40(10): 996-998. Abstract [View PDF] [Read Full Text] Retinal neovascularization (RNV) originating from retinal blood vessels is one of the main pathological features of many ocular […]
Expression and determination of biomarkers in diabetic retinopathy
Authors: Jiang Yilin, Zhang Xiaomin, Li Xiaorong DOI: 10.3760/cma.j.cn115989-20200417-00269 Published 2022-09-10 Cite asChin J Exp Ophthalmol, 2022, 40(9): 859-863. Abstract [View PDF] [Read Full Text] Diabetic retinopathy (DR) is a kind of common vascular complications in diabetes and one of the leading […]
Research progress of inflammatory cytokines in intraocular fluid of diabetic macular edema
Authors: Hong Yiyi, Sun Xufang DOI: 10.3760/cma.j.cn115989-20200610-00417 Published 2022-09-10 Cite asChin J Exp Ophthalmol, 2022, 40(9): 864-868. Abstract [View PDF] [Read Full Text] Diabetic macular edema is a common complication of diabetic retinopathy, and is the main cause of vision decline.Antivascular endothelial […]
Application of proteomics in exploring the inflammatory biomarkers of diabetic retinopathy
Authors: Xu Manhong, Li Xiaorong DOI: 10.3760/cma.j.cn115989-20200428-00294 Published 2022-09-10 Cite asChin J Exp Ophthalmol, 2022, 40(9): 869-873. Abstract [View PDF] [Read Full Text] Diabetic retinopathy (DR) is a common neurovascular complication of diabetes patients, which seriously threatens the vision health of working-age […]
Progress on the phenotype of human corneal stromal cells
Authors: Yang Yi, Niu Yang, Yuan Ling DOI: 10.3760/cma.j.cn115989-20200626-00455 Published 2022-09-10 Cite asChin J Exp Ophthalmol, 2022, 40(9): 874-879. Abstract [View PDF] [Read Full Text] Human corneal stromal cells (HCSCs), a type of resting neural crest mesenchymal cell, are highly specialized transparent […]