Category: Review

Application of artificial intelligence technologies in ocular anterior segment diseases diagnosis and myopia management

Authors: Zhou Yiwen,  Yang Yanning DOI: 10.3760/cma.j.cn115989-20201014-00692 Published 2021-09-10 Cite asChin J Exp Ophthalmol, 2021, 39(9): 821-826. Abstract With the improvement of computing power, the refinement of learning algorithms and architectures and the disclosure of big data, many achievements pertaining to artificial intelligence (AI) have been achieved in the field of medicine.In the field of […]

Current status and directions of vision rehabilitation in glaucoma

Authors: Huang Haishun,  Li Yiqing,  Zhuo Yehong DOI: 10.3760/cma.j.cn115989-20200119-00783 Published 2021-09-10 Cite asChin J Exp Ophthalmol, 2021, 39(9): 827-831. Abstract Glaucoma, the leading cause of irreversible visual impairment in the world, leads to visual function damage that seriously affects the daily life activities and psychosocial function of patients, resulting in a significant decline in the […]

New diagnosis and treatment pattern for cataract based on artificial intelligence

Authors: Wang Ting,  Wang Ruixin,  Lin Haotian DOI: 10.3760/cma.j.cn115989-20200608-00405 Published 2021-09-10 Cite asChin J Exp Ophthalmol, 2021, 39(9): 832-836. Abstract With the increase in the aging of the global population, the prevalence of cataract has increased gradually, and cataract has become a significant cause of blindness and visual impairment in China and even in the […]

Research progress in the clinical features of reticular macular disease

Authors: Diao Yuyao,  Cheng Hao DOI: 10.3760/cma.j.cn115989-20190216-00055 Published 2021-09-10 Cite asChin J Exp Ophthalmol, 2021, 39(9): 837-840. Abstract Reticular macular disease (RMD) is a novel, independent macular disease closely related to age-related macular degeneration (AMD). It is currently available to identify RMD through a variety of new imaging techniques.The infrared imaging in the confocal scanning […]

Non-viral vector for gene therapy in inherited retinal degeneration

Authors: Wei Xing,  Sui Ruifang DOI: 10.3760/cma.j.cn115989-20200627-00457 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 737-742. Abstract Inherited retinal degeneration (IRD), a group of diseases often causing irreversible blindness, with multiple pathogenesis, still lacks effective treatments currently.Development of effective therapeutics is a primary research goal.Despite rapid advances in gene therapy during the past decades, […]

Role of circRNA in ophthalmic diseases

Authors: Yang Guang,  Zhang Dan,  Ma Xiaopeng DOI: 10.3760/cma.j.cn115989-20191011-00437 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 743-748. Abstract Circular RNA (circRNA) is a closed loop molecule generated by the back-splicing of pre-mRNA.CircRNA can act as microRNA (miRNA) sponge or combine with proteins and RNAs to form complexes, having functions of regulating the host […]

Related clinical trials and prospects of gene therapy for neovascular age-related macular degeneration

Authors: Zhang Wei,  Yan Hua DOI: 10.3760/cma.j.cn115989-20210113-00033 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 749-754. Abstract Neovascular macular degeneration (nAMD) is one of the main eye diseases causing blindness in the elderly population.Early detection and early treatment are particularly important.At present, the treatment of nAMD is mainly symptomatic, including anti-vascular endothelial growth factor […]

Characteristics of autosomal dominant retinal diseases and gene therapy strategies

Authors: Liu Yanbo, Pang Jijing DOI: 10.3760/cma.j.cn115989-20210329-00215 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 755-760. Abstract Inherited retinal diseases (IRDs), one type of the major eye diseases resulting in blindness, can be caused by more than 270 identified causative genes.The most common form of IRDs is retinitis pigmentosa.There is no generally accepted cure […]

Research progress of intravitreal injections for nonarteritic anterior ischemic optic neuropathy

Authors: He Lu,  Chen Changzheng DOI: 10.3760/cma.j.cn115989-20201104-00739 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 641-644. Abstract Nonarteritic anterior ischemic optic neuropathy (NAION) is a common type of acute optic neuropathy in elderly, characterized by optic disc edema and visual field defect.At present, there is no generally accepted treatment, and the treatment of NAION […]

Advances in the treatment of idiopathic macular epiretinal membrane

Authors: Jiao Mingfei,  Li Xiaorong DOI: 10.3760/cma.j.cn115989-20201104-00738 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 645-648. Abstract Idiopathic epiretinal membrane (iERM) is one of common fibroblast proliferative diseases in vitreoretinal interface and is significantly associated with aging.The treatment and management methods of iERM are limited, primarily including clinical following-up and vitrectomy.The time point of […]