Category: Review

RNA-seq and its application in diabetic retinopathy

Authors: Nie Zetong,  Hu Bojie DOI: 10.3760/cma.j.cn115989-20190806-00337 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 450-453. Abstract RNA-seq is a transcriptome analysis method using deep sequencing technology, which uses high-throughput next-generation sequencing technology to investigate, characterize and quantify transcriptome.It can quickly and comprehensively detect almost all transcripts and gene sequences of specific cells in […]

Application of corneal densitometry in clinical practices

Authors: Guo Hanchao,  Ren Shengwei,  Zhao Dongqing DOI: 10.3760/cma.j.cn115989-20200723-00523 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 454-458. Abstract Corneal densitometry is a biological property of corneal tissue, which is related to the transparency of cornea, and can be used to describe the degree of corneal transparency.At present, corneal densitometry has been used in […]

Research progress and problems of retinal pigment epithelium transplantation

Authors: Li Teng,  Chen Xiaodong DOI: 10.3760/cma.j.cn115989-20190820-00356 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 459-463. Abstract In recent years, promising results have been achieved in retinal pigment epithelium (RPE) cell transplantation in the treatment of diseases such as age-related macular degeneration.The types of transplanted RPE cells include autologous RPE cells, autologous iris pigment […]

Research progress of programmed cell death 1 and its receptor programmed cell death 1 ligand 1 in the pathogenesis of eye diseases

Authors: Tian Xuelian,  Tang Li DOI: 10.3760/cma.j.cn115989-20190912-00393 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 464-468. Abstract Programmed cell death 1 (PD-1) is an important negative costimulatory molecule discovered in recent years, which is expressed on the surface of T and B cells and plays an important role in the regulation of cellular immune […]

Clinical characteristics and surgical repair of ethmo-maxillary bone buttress in orbital blowout fractures

Authors: Zhu Jiawei,  Zhou Zhongyou DOI: 10.3760/cma.j.cn115989-20200713-00490 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 469-472. Abstract Ethmo-maxillary bone buttress (EMBB) is a special complex bone structure in the interface between the internal wall and inferior wall of the orbit, which plays a vital role in maintaining the stability of the orbit, ethmoidal sinus […]

Research updates on strabismus associated with congenital cataract

Authors: Wu Yazhen,  Yan Hong DOI: 10.3760/cma.j.cn115989-20190401-00159 Published 2021-04-10 Cite asChin J Exp Ophthalmol, 2021, 39(4): 346-350. Abstract Patients with congenital cataract often present strabismus simultaneously.Strabismus is closely related to the occurrence of cataract, and is one of the main threats for the development of binocularity and the therapeutic effect of amblyopia.In addition, strabismus negatively […]

Research progress on the application of three-dimensional display technology in ophthalmic surgery

Authors: Zhu Lin,  Chen Yiqi,  Shen Lijun DOI: 10.3760/cma.j.cn115989-20190222-00073 Published 2021-04-10 Cite asChin J Exp Ophthalmol, 2021, 39(4): 351-355. Abstract Based on binocular disparity, three-dimensional (3D) display technology makes the right and left eyes see different images in a certain way, which generates a stereo image after the processing of the brain’s visual cortex.Due to […]

Role of eye rubbing in the occurrence and development of keratoconus

Authors:  Li Dan,  Ren Shengwei,  Zhao Dongqing DOI: 10.3760/cma.j.cn115989-20200602-00391 Published 2021-04-10 Cite asChin J Exp Ophthalmol, 2021, 39(4): 356-359. Abstract Keratoconus is a progressive and bilateral corneal disease with the characteristics of the protrusion of the dilated and central thinning cornea.Keratoconus often causes myopia and irregular astigmatism, and corneal edema and scarring in the late […]

Role and mechanism of Müller cells in diabetic macular edema

Authors: Zhu Shaojin,  Fang Yan DOI: 10.3760/cma.j.cn115989-20200226-00111 Published 2021-04-10 Cite asChin J Exp Ophthalmol, 2021, 39(4): 360-364. Abstract Müller cells, as the special radial glial cells in the retina, span the entire retina, contact with neurons, microvessels and processes in the retina and play a significant role in protecting retinal structure and function.Diabetic retinopathy (DR) […]