Authors:Liu Mengxin, Yan Chunxiao,Zhang Lijun Corresponding author: Zhang Lijun, Email: lijunzhangw@sina.com Published:2026-07-10 DOI:10.3760/cma.j.cn115989-20240923-00266 ABSTRACT Corneal neovascularization (CNV) is a common pathological change in many eye diseases, such as infections, inflammation, hypoxia, degeneration, and trauma, which can cause serious visual impairment. Inflammation is the core mechanism of CNV, and various immune cells (macrophages, neutrophils, T cells, and antigen-presenting cells) […]
Category: Review
Oxidative stress-induced mechanisms in corneal neovascularization and targeted therapeutic approaches
Authors:Deng Qian, Wan Shanshan, Yang Yanning Corresponding author: Yang Yanning, Email: yangyanning@whu.edu.cn Published:2026-07-10 DOI:10.3760/cma.j.cn115989-20240229-00056 ABSTRACT Corneal neovascularization (CNV) is an ocular surface disorder caused by a variety of diseases, including inflammation, trauma, malnutrition, wearing of corneal contact lenses, etc. Oxidative stress refers to the excessive production of reactive oxygen species or reactive nitrogen species in […]
The anatomy, physiology and mechanism of vortex veins in ocular diseases associated with vortex vein dysfunction
Authors: Yang Xieke, Yan Ming, Song Yanping Corresponding author: Song Yanping, Email: drsongyanping@163.com Published:2026-07-10 DOI: 10.3760/cma.j.cn115989-20250303-00061 ABSTRACT The vortex vein, serving as the sole drainage pathway for the choroidal veins, plays a pivotal role in the pathogenesis of various ocular diseases due to its anatomical variations and physiological dysfunctions. This article systematically reviews the anatomical and physiological characteristics of the […]
Current research status of retinal ciliopathy
Authors: Fan Xue, Rong Weining Corresponding author: Rong Weining, Email: moc.621624gniniewgnor Published:2026-07-10 DOI: 10.3760/cma.j.cn115989-20230731-00054 ABSTRACT Cilia widely exist in most cell types of the human body, and the dysfunction of cilia can affect various organs. The outer segment of the photoreceptor is a kind of highly differentiated primary sensory cilium, and its structure and function […]
Application of molecular diagnostic technology in the diagnosis of infectious eye diseases
Authors: Li Panpan, Guan Huaijin Corresponding author: Guan Huaijin, Email: guanhuaijinleye@126.com Published:2026-07-10 DOI: 10.3760/cma.j.cn115989-20231124-00184 ABSTRACT The clinical diagnosis of infectious diseases mainly relies on the isolation and culture of pathogenic microorganisms, but many infectious eye diseases have problems such as acute onset, difficulty in obtaining samples, and difficulty in diagnosis. Compared with traditional microbial culture, […]
Advances in CNGA1-related autosomal recessive retinitis pigmentosa
Authors: Liu Yue, Zou Xuan, Sui Ruifang Corresponding author: Sui Ruifang, Email: hrfsui@163.com Published:2026-06-10 DOI: 10.3760/cma.j.cn115989-20250407-00111 ABSTRACT The CNGA1 gene encodes the alpha subunits of the rod cyclic nucleotide-gated channel, which binds to intracellular cyclic guanosine monophosphate and constitutes the last step of converting light stimulation into an electrical signal in photoreceptor rod cells. The CNG channel plays […]
Research progress on chronic inflammation in wet age-related macular degeneration
Authors: Xu Songyu, Zhuo Qiao, Sun Ye, Zhang Shujie, Zhao Chen Published: 2026 -06 -10 DOI: 10.3760/cma.j.cn115989-20250918-00306 Citation Xu Songyu, Zhuo Qiao, Sun Ye, et al. Research progress on chronic inflammation in wet age-related macular degeneration[J]. Chin J Exp Ophthalmol, 2026, 44(6):576-583. DOI: 10.3760/cma.j.cn115989-20250918-00306. ABSTRACT [Download PDF] [Read Full […]
Progress in the treatment of corneal neovascularization with anti-VEGF drugs
Authors: Li Shiding, Chen Liangbo, Fu Yao Published: 2026 -06 -10 DOI: 10.3760/cma.j.cn115989-20230601-00206 Citation Li Shiding, Chen Liangbo, Fu Yao. Progress in the treatment of corneal neovascularization with anti-VEGF drugs[J]. Chin J Exp Ophthalmol, 2026, 44(6):584-589. DOI: 10.3760/cma.j.cn115989-20230601-00206. ABSTRACT [Download PDF] [Read Full Text] The cornea is an important refractive […]
Application progress of gene therapy targeting vascular endothelial growth factor in ocular fundus vascular diseases
Authors: Bao Yanbo, Xie Zhenggao Published: 2026 -06 -10 DOI: 10.3760/cma.j.cn115989-20250709-00226 Citation Bao Yanbo, Xie Zhenggao. Application progress of gene therapy targeting vascular endothelial growth factor in ocular fundus vascular diseases[J]. Chin J Exp Ophthalmol, 2026, 44(6):590-598. DOI: 10.3760/cma.j.cn115989-20250709-00226. ABSTRACT [Download PDF] [Read Full Text] The pathogenesis of ocular vascular […]
Research progress of m6A RNA methylation modification in ocular disease
Authors: Liu Qing, Jiang Qin Published: 2026 -06 -10 DOI: 10.3760/cma.j.cn115989-20230620-00010 Citation Liu Qing, Jiang Qin. Research progress of m6A RNA methylation modification in ocular disease[J]. Chin J Exp Ophthalmol, 2026, 44(6):599-606. DOI: 10.3760/cma.j.cn115989-20230620-00010. ABSTRACT [Download PDF] [Read Full Text] N6-methyladenosine (m6A) methylation is the common internal […]