Category: Review

Application of proteomics in age-related macular degeneration

Authors: Yang Fan,  Sun Xiaodong DOI: 10.3760/cma.j.cn115989-2019-0105-00006 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 72-77. Abstract Age-related macular degeneration (AMD) is the mainirreversible blinding eye disease in the elderly.Its main pathogenic factors include age, genetic variation and lifestyle, but the specific pathogenesis has not been fully elucidated.As an emerging research method, proteomics technology […]

Research progress on pachychoroid disease

Authors: Yin Xinkai,  Dai Rongping DOI: 10.3760/cma.j.cn115989-20200706-00478 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 78-83. 【Read Full Text】  【Download PDF】 Abstract Pachychoroid disease is a relatively novel concept proposed in ophthalmology in recent years, which describes a series of pathological conditions including chronic persistent choroidal thickening and choroidal vasodilatation, with choroid blood capillary […]

Progress in the treatment of refractory macular hole

Authors: Shi Yunhong,  Zhang Shaochong DOI: 10.3760/cma.j.cn115989-20190917-00396 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 84-88. 【Read Full Text】  【Download PDF】 Abstract Refractory macular hole (MH) includes large MH, traumatic MH, secondary MH, high myopic MH, unclosed MH and reopening MH.Refractory macular hole (MH) still has low anatomical closure rate and poor recovery of […]

Research progress in biomarkers of diabetic macular edema on optical coherence tomography

Authors: Jiang Jingwen,  Chen Changzheng DOI: 10.3760/cma.j.cn115989-20190617-00264 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 89-92. Abstract Diabetic retinopathy (DR) is a common ocular complication in patients with diabetes, and diabetic macular edema (DME) is the main cause of vision loss in patients with DR, so the early diagnosis and treatment of DME is […]

Influence of smoking on the occurrence and development of age-related macular degeneration

Authors: Zhang Zhicheng,  Zhang Meixia DOI: 10.3760/cma.j.cn115989-20201104-00736 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 93-96. Abstract Age-related macular degeneration (AMD) causes vision loss mainly due to apoptosis of retinal pigment epithelium cells and subsequent degeneration of photoreceptors.Active and passive smoking can increase the incidence of AMD and the progression risk of advanced AMD, […]

Application of network pharmacology in ophthalmology

Authors: Liu Juping,  Li Xiaorong DOI: 10.3760/cma.j.cn115989-20200224-00104 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1083-1086. Abstract Network pharmacology is a branch of pharmacology, and it primarily studies the complex biological network relationship among drugs, genes, targets and diseases through biological network construction, network analysis and experimental verification of expected results.Network pharmacology has its […]

Mechanism and clinical application of diquaphosol sodium ophthalmic solution in dry eye patients

Authors: Wang Yili, Gong Lan DOI: 10.3760/cma.j.cn115989-20200804-00560Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1087-1090. Abstract Chinese dry eye consensus 2020 updated the definition and classification of dry eye, stressing tear-film instability as the core mechanism of dry eye.The classification criteria are complemented with tear component abnormality as an important category.As a P2Y2 receptor […]

Advances of ocular surface drug delivery system

Authors: Chen Xiang,  Xu Wen DOI: 10.3760/cma.j.cn115989-20200123-00038 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1091-1096. Abstract Due to the anatomical and physical barriers, the low bioavailability of eye drops has become the primary problem in optimizing efficacy.Drug delivery system can reduce administration frequency and keep the therapeutic concentration while increasing ocular surface retention […]

Epidemiological features of orbital lymphoma

Authors: Sun Mei,  Ma Jianmin  DOI: 10.3760/cma.j.cn115989-20191009-00432 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 979-982. Abstract Orbital lymphoma, mainly composed of B-lymphocytes lymphoma and rare T-lymphocytes lymphoma, is the most frequent malignancy of the ocular adnexa.Orbital lymphoma is normally classified into different subtypes according to the origin of lymphocytes.For instance, extranodal marginal zone […]

New progress in the orbital tumor treatment technology

Authors: Yu Jinhai,  Xu Qihua,  Liao Hongfei DOI: 10.3760/cma.j.cn115989-20200924-00664 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 983-988. Abstract Orbital tumors not only damage the appearance of patients, but also damage the visual function, even endanger the life of patients.Orbital tumors can be divided into epidermal ectoderm, neuroectoderm, mesoderm, lymphopoietic system and metastatic tumors […]