Category: Editorial

Promoting the research and development of drug for cataract and reducing the blindness rate of cataract

Author: Wang Yandong DOI: 10.3760/cma.j.cn115989-20201102-00726 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1001-1003. Abstract With the aging of the population and changes of people’s lifestyle, age-related eye disease, metabolic-related eye disease and fundus lesions caused by high myopia become the main causes of blindness in China.Up to now, the only therapy for age-related […]

The importance of basic research and drug development for thyroid-associated ophthalmopathy

Author: Fan Xianqun DOI: 10.3760/cma.j.cn115989-20200812-00582 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 905-909. Abstract Thyroid-associated ophthalmopathy (TAO) is an organ specific autoimmune disease with complex pathogenesis.In recent years, great progress has been made in the pathogenesis of TAO primarily in immune and molecular mechanism aspects, including related autoantigens, lymphocytes, inflammatory factors, and autoimmune […]

Paying close attention to advanced researches of ocular surface mucin and significance in the diagnosis and management of dry eye

Author: Hong Jing DOI: 10.3760/cma.j.cn115989-20200715-00499 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 910-915. Abstract As an important part of the tear film, mucin can be divided into secretory mucin and membrane-associated mucin according to different functions.Secretory mucin, secreted by goblet cells, plays a key role in maintaining the stability of the tear film, […]

Current research and challenge of human retinal organoid differentiation

Authors: Luo Ziming,  Ge Jian DOI: 10.3760/cma.j.cn115989-20200721-00518 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 809-812. Abstract The retinal organoid is one of the most widely studied organoids in vitro, which is an “organ in a dish” with a highly similar tissue structure to those in vivo.Since it was first reported, the differentiation methods […]

A metabolic perspective in diabetic ocular disease

Authors: Shao Yan,  Li Xiaorong DOI: 10.3760/cma.j.cn115989-20200527-00377 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 729-732. Abstract Cellular energy metabolism including glycolysis and lipid oxidation provides energy to all the fundamental activities in living cells.The metabolic profile indicated by the balance between glycolysis and lipid oxidation plays a critical role in the determination of […]

Gene therapy for retinal diseases: global progress and challenges

Authors: Wu Zhijian DOI: 10.3760/cma.j.cn115989-20200716-00500 Published 2020-08-10 Cite as Chin J Exp Ophthalmol, 2020,38(08): 633-638. Abstract In the past three decades, we have witnessed the great promise of gene therapy in treating a variety of inherited and acquired retinal diseases. The large number of preclinical studies in retinal gene therapy has led to over sixty clinical […]

To correctly analyze ultra-wide field fluorescein angiography in peripheral retina

Authors: Chen Changzheng,  Wang Xiaoling DOI: 10.3760/cma.j.cn115989-20190401-00158 Published 2020-07-10 Cite as Chin J Exp Ophthalmol, 2020,38(07): 562-565. Abstract Ultra-wide field fluorescein angiography (UWFFA) is a new technique emerging in recent years.UWFFA can observe the fluorescence signs of wide areas of retina beyond the traditional 7-field of vision.UWFFA has obvious advantages in peripheral retina of vascular diseases, […]

Implementing a prevention and control of ametropia in accordance with Specification for Screening of Refractive Error in School-age Children and Adolescents

Authors: Zou Haidong,  He Xiangui,  Ma Yingyan,  Ma Jun,  Dong Bin,  Xu Xun DOI: 10.3760/cma.j.cn115989-20200113-00024 Published 2020-06-10 Cite as Chin J Exp Ophthalmol, 2020,38(06): 473-475. Abstract Ametropic visual impairment has become a public health problem in China and even in the world, especially the prevention and control of myopia development, and the Chinese government attaches great […]

Actively carry out the molecular genetic study of glaucoma in children

Authors: Chen Xueli,  Chen Yuhong,  Chen Junyi,  Sun Xinghuai DOI: 10.3760/cma.j.cn115989-20200420-00274 Published 2020-05-10 Cite as Chin J Exp Ophthalmol, 2020,38(05): 377-380. Abstract The pathogenesis and clinical manifestations of glaucoma in children are quite complex and diverse.Because the visual function of childhood is in a developing stage, even the intraocular pressure is controlled well, the visual function […]

Standardized application of minimally invasive pars plana vitrectomy for complicated cataract

Authors: Chen Weirong,  Wang Qiwei DOI: 10.3760/cma.j.cn115985.20200325-00199 Published 2020-04-10 Cite as Chin J Exp Ophthalmol, 2020,38(04): 281-284. Abstract Phacoemulsification, an effective surgical method in the treatment of cataracts, is widely used in clinics.Traditional cataract surgery is difficult, risky and has a poor prognosis for special intractable cataract patients.Minimally invasive pars plana vitrectomy (PPV) is the a […]