Category: Current Issue

Chinese experts consensus for the intravitreal injection of aflibercept treating diabetic macular edema (2021)

Author: Intravitreal Injection of Aflibercept for Diabetic Macular Edema Experts Consensus Group DOI: 10.3760/cma.j.cn115989-20210202-00088 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 369-375. Abstract                                            【Read Full Text】【Download PDF】 Diabetic macular edema (DME) is […]

Multiple fundus imaging diagnosis: knowing the principles well for a rational application

Authors: Wen Feng,  Hua Rui DOI: 10.3760/cma.j.cn115989-20210302-00140 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 376-381. Abstract                                            【Read Full Text】  【Download PDF】 Multimodal fundus imaging techniques, based on lights and shadows, appear to […]

Proteomics analysis of mouse lens supernatant treated with hydrogen peroxide in vitro

Authors: Li Guo,  Chen Ying,  Yan Hong,  Zhou Xiyuan DOI: 10.3760/cma.j.cn115989-20200730-00546 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 382-387. Abstract Objective To study the protein leakage of mouse lens treated with hydrogen peroxide in vitro, and to identify and carry out bioinformatics analysis of the leaked proteins. Methods Intact binocular lenses of 42 […]

Construction of Crx-iCreERT2 fluorescent reporter human embryonic stem cells by CRISPR/Cas9 technology and 3D retinal organoid culture

Authors: Du Yuxin,  Liu Yizong,  Yan Feiyue,  Shen Yin DOI: 10.3760/cma.j.cn115989-20210208-00103 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 388-397. Abstract Objective To establish Crx-iCreERT2 fluorescent reporter human embryonic stem cell lines using CRISPR/Cas9 technology and 3D retinal organoid culture. Methods The target site sequence of H9 cell line was verified by polymerase chain […]

Inhibitory effect of miR-146a on high glucose-induced apoptosis of retinal microvascular endothelial cells and its mechanism

Authors:  Gao Fei,  Wu Zhipeng,  Ruan Yihua DOI: 10.3760/cma.j.cn115989-20190703-00286 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 398-403. Abstract Objective To investigate the effect of microRNA-146a (miR-146a) on apoptosis of human retinal microvascular endothelial cells (HRMECs) induced by high glucose and its possible molecular mechanism. Methods HRMECs were cultured in vitro with 5.5 mmol/L […]

Effectiveness and safety evaluation of lidocaine hydrochloride ophthalmic gel for ocular anesthesia: a multicenter randomized double-blind trial

Authors: Zhao Jing,  Zhao Mingwei,  Yao Tao,  Cui Hongping,  Wang Yong,  Jin Xuemin,  Han Qi,  Liu Fang,  Li Qiuming,  Chen Xueyi,  Dai Hong DOI: 10.3760/cma.j.cn115989-20201216-00844 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 404-409. Abstract Objective To evaluate the effectiveness and safety of 3.5% lidocaine hydrochloride ophthalmic gel for eye surface anesthesia. Methods A […]

Measurement and analysis of corneal biological parameters from Tibetan junior middle school students in high altitude area

Authors: Danzengrenqing,  Miao Heng,  Tsedenyangky,  De ji,  Zhao Mingwei DOI: 10.3760/cma.j.cn115989-20210219-00119 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 410-415. Abstract Objective To measure and analyze the corneal biological parameters of Tibetan junior middle school students who have lived in Mozhugongka County of Lhasa city for a long time. Methods A cross-sectional study was […]

Establishment and verification of the multi-dimensional peripheral contrast sensitivity function measurement based on Bayesian probability estimation algorithm

Authors: Chen Zhipeng,  Zhuang Yijing,  Xu Zixuan,  Hou Fang,  Ye Qingqing,  Jia Yu,  He Yunsi,  Zhou Yusong,  Zhang Shenglan,  Feng Lei,  Lyu Zhonglin,  Li Jinrong DOI: 10.3760/cma.j.cn115989-20210120-00058 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 417-422. Abstract Objective To evaluate the feasibility and accuracy of a multi-dimensional peripheral quick contrast sensitivity function (pqCSF) measurement […]

Comparison of myopia progression between different concentrations and application frequencies of atropine eye drops in children

Authors: Qin Jian,  Lyu Yong,  Wei Li,  Zhang Junjie,  Zhao Bingxin,  Fu Aicun DOI: 10.3760/cma.j.cn115989-20200101-00015 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 423-429. Abstract Objective To compare the clinical effect of 0.02% atropine eye drops once every two days and 0.01% atropine eye drops once every day in myopia control and adverse reactions […]

Evaluation and comparison of early outcome and corneal biomechanical changes between SMILE-corneal collagen cross linking and SMILE for myopic eyes

Authors: Jiang Sha,  Lei Xiaohua,  Tan Weina,  Shu Bao DOI: 10.3760/cma.j.cn115989-20191208-00529 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 430-438. Abstract Objective To evaluate early corneal biomechanical change, safety and effectiveness after small-incision lenticule extraction combined with ultraviolet A corneal collagen cross-linking (SMILE-CXL) for myopic eyes and compare with SMILE. Methods A non-randomized controlled […]