Category: Current Issue

A metabolic perspective in diabetic ocular disease

Authors: Shao Yan,  Li Xiaorong DOI: 10.3760/cma.j.cn115989-20200527-00377 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 729-732. Abstract Cellular energy metabolism including glycolysis and lipid oxidation provides energy to all the fundamental activities in living cells.The metabolic profile indicated by the balance between glycolysis and lipid oxidation plays a critical role in the determination of […]

Inhibitory effects of miR-146a on retinal inflammation induced by high glucose in human retinal endothelial cells

Authors: Gu Shun,  Zhan Pengfei,  Wang Wenjuan,  Wang Xiaolu,  Wei Tingting,  Zhu Lingpeng,  Wang Yangningzhi,  Yin Li,  Xie Tianhua,  Yao Yong DOI: 10.3760/cma.j.cn115989-20190213-00051 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 733-739. Abstract Objective To observe the effects of miR-146a on human retinal endothelial cell (HREC) under high glucose condition. Methods Total of 57 […]

Effect of recombinant human vascular endostatin on retinal barrier related proteins in early diabetic rats

Authors: Zhou Jinhua,  Xie Zhenggao DOI: 10.3760/cma.j.cn115989-20190228-00092 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 740-745. Abstract Objective To observe the effect of recombinant human vascular endostatin(ES) on retinal barrier related proteins in early streptozotocin (STZ)-induced diabetic rats. Methods Diabetes rat model was induced by STZ.Two weeks after the model was successfully constructed, 36 […]

Application of virus tracing tools in the study of function and morphology of neurons in the visual circuit

Authors: Shen Kejiong,  Shen Yin DOI: 10.3760/cma.j.cn115989-20191021-00457 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 746-753. Abstract Objective To utilize four viral tracer tools with different properties, to visualize cell morphology and connectome in visual pathways and explore and summarize the applications of different viral tracer tools in visual circuit, basing on the technology […]

Novel mutation in the CRB1 gene in a family affected with Leber congenital amaurosis

Authors: Peng Haiying,  Zhou Zhongqiang,  Shi Pingling,  Tang He,  Wei Yuanmeng,  Li Miao,  Liang Yingjuan,  Nie Xiaodong,  Huang Aiguo DOI: 10.3760/cma.j.cn115989-20190813-00347 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 780-782. Contributor Information Peng Haiying Henan Province People’s Hospital, Henan Eye Hospital, Henan Eye Institute, People’s Hospital of Zhengzhou University, Zhengzhou 450003, China Zhou Zhongqiang […]

Interpretation of Diabetic Retinopathy Preferred Practice Pattern®

Authors: Li Xiaorong,  Yang Qianhui DOI: 10.3760/cma.j.cn115989-20200518-00350 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 795-798. Abstract The numbers of population with diabetes have risen sharply worldwide.China has become a country with high incidence of diabetes.Diabetic retinopathy (DR), as a crucial microvascular complication of diabetes, has become one of the major ocular diseases causing […]

Research progress of exosomes in diabetic retinopathy

Authors: Zhang Hui,  Zhang Xiaomin,  Li Xiaorong DOI: 10.3760/cma.j.cn115989-20200424-00285 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 799-803. Abstract Exosomes are small extracellular vesicles secreted by cells and carry many biological molecules, such as mRNA, microRNA, proteins, and transcription factors.Exosomes play a role in mediating intercellular communication in normal physiological processes.In the pathological state, […]

Application of machine learning in auxiliary diagnosis of corneal related diseases

Authors: Zhang Zijun,  Liang Qingfeng DOI: 10.3760/cma.j.cn115989-20200201-00045 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 804-808. Abstract Machine learning, as the main technical direction of artificial intelligence, can help ophthalmologists to interpret and analyze the large amount of data generated by imaging equipment, and also simplify the diagnosis and treatment process.The early diagnosis and […]

Changes of serum complement factors in patients with diabetic retinopathy

Authors: Sun Hongyan,  Ma Ruirui,  Chen Jiayu,  Yu Xuhui,  Yang Mingming DOI: 10.3760/cma.j.cn115989-2019051-00212 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 754-759. Abstract Objective To detect the changes of serum complement factors C3 and C4 in diabetic retinopathy (DR) patients, and to explore their role in the occurrence and development of DR. Methods A […]

Changes of brain function in resting-state in patients with nonproliferative diabetic retinopathy assessed by fractional low-frequency amplitude technique

Authors: Qi Chenxing,  Huang Xin,  Tong Yan,  Shen Yin DOI: 10.3760/cma.j.cn115989-20190920-00406 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 760-765. Abstract Objective To study the changes of brain function in patients with diabetic retinopathy (DR) by using resting-state functional magnetic resonance imaging (rs-fMRI) based on the fractional amplitude of low-frequency fluctuation (fALFF) method. Methods […]