Category: Current Issue

Repeated low-level red-light therapy: a novel method for myopia prevention and control

Authors: Zhu Zhuoting,  He Mingguang DOI: 10.3760/cma.j.cn115989-20220127-00031 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 487-490. Abstract China has recently proposed a countrywide myopia control strategy for children and adolescents due to the rapidly increasing incidence and early onset of myopia.Recent studies have proposed interventions and methods for myopia prevention and control, such as […]

Effects of different intensity of lighting on refractive development and form deprivation myopia in guinea pigs

Authors: Li Congying,  Gan Jiahe,  Wang Meijun,  Cao Beihe,  Huang Ying,  He Xi,  Hua Ziyu,  Sun Minghao,  Li Shiming DOI: 10.3760/cma.j.cn115989-20220228-00079 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 491-497. Abstract Objective To investigate the effects of different intensity of lighting on normal refractive development and form deprivation myopia (FDM) in guinea pigs. Methods […]

Inhibitory effect of siRNA-Pax6 on biological behavior and epithelial-mesenchymal transition of human lens epithelial cells

Authors: Zheng Yuxing,  Yang Xiaoxi,  Yi Guoguo,  Wu Shuduan,  Feng Zhizhen,  Xia Zhaoxia DOI: 10.3760/cma.j.cn115989-20210423-00272 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 499-506. Abstract Objective To explore the effect of knockdown of the homeobox gene paired-box 6 (Pax6) on the biological behavior and epithelial-mesenchymal transition (EMT) of human lens epithelial cells (LECs). Methods […]

Inhibitory effects of NADPH oxidase 4 inhibitor on the epithelial-mesenchymal transition of human RPE cells induced by bevacizumab

Auhtors: Xie Chaohui,  Hao Xianghui,  Yang Lingling,  Xu Haifeng DOI: 10.3760/cma.j.cn115989-20210407-00234 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 507-513. Abstract Objective To observe the influence of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) 4 inhibitors on epithelial-mesenchymal transition (EMT) of human retinal pigment epithelial (RPE) cells induced by bevacizumab. Methods The cultured ARPE-19 […]

Inhibitory effect of siRNA-KCNQ1OT1 on human lens epithelial cell apoptosis by targeting miR-199a-5p

Authors: Lu Cheng,  Zhang Fengyan,  Zhang Yuhang,  Zhang Jiajuan DOI: 10.3760/cma.j.cn115989-20210427-00280 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 514-523. Abstract Objective To explore the inhibitory effect of long non-coding RNA (lncRNA) KCNQ1 overlapping transcript 1 (KCNQ1OT1) by targeting microRNA-199a-5p (miR-199a-5p) on the apoptosis of human lens epithelial cells (LECs). Methods The anterior lens […]

Influence and significance of angle Kappa on total ocular aberrations before and after SMILE surgery

Authors: Shao Ting,  Wang Yan,  Hao Weiting,  Zhang Jiamei,  Cui Tong DOI: 10.3760/cma.j.cn115989-20190305-00098 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 525-532. Abstract Objective To investigate the influence of angle Kappa on total high-order aberration (HOA) before and after small incision lenticule extraction (SMILE). Methods An observational case series study was conducted.Right eyes of […]

Effects of 0.01% atropine eye drops on the prevention of myopia onset among schoolchildren: a randomized, double-blind, controlled trial

Authors: Yu Shiao,  Lyu Yong,  Wang Weiqun,  Cui Can,  Wei Li,  Huang Congcong,  Ma Nana,  Zhao Bingxin,  Zhang Junjie,  Fu Aicun DOI: 10.3760/cma.j.cn115989-20210821-00470 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 533-540. Abstract Objective To observe the safety and efficacy of 0.01% atropine eye drops in the prevention of myopia onset in schoolchildren. Methods […]

Clinical evaluation of vision therapy system 4 combined with traditional comprehensive training for ametropic amblyopia

Authors: Chi Yingjie,  Wang Huajun,  Li Xiao,  Luo Yao,  Zheng Guangying DOI: 10.3760/cma.j.cn115989-20211008-00555 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 541-547. Abstract Objective To assess the effectiveness of Vision Therapy System 4 (VTS4) combined with traditional comprehensive training for ametropic amblyopia. Methods A non-randomized controlled clinical study was performed.A total of 168 children […]

Distribution characteristics of choroidal thickness in normal population and the diagnostic cut-off value for pachychoroid

·Clinical Research· Distribution characteristics of choroidal thickness in normal population and the diagnostic cut–off value study for pachychoroid  Zhang Xinyuan1&, Qiu Bingjie1, Wang Yanhong2, Li Zhiqing3, Zeng Yiyun1, Chen Xiaosi1 1Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Institute of Ophthalmology and Visual Sciences, Beijing 100730, China; 2Department of […]