Category: Clinical Science

Changes in neutrophil-to-lymphocyte ratio in different subtypes of diabetic retinopathy

Authors:Wang Manqiao, Liu Boshi, Li Xiaorong Corresponding author: Li Xiaorong, Email: xiaorli@163.com Published:2026-09-10 DOI: 10.3760/cma.j.cn115989-20260331-00149 ABSTRACT  Objective To investigate the changes in the neutrophil-to-lymphocyte ratio (NLR) in different subtypes of diabetic retinopathy (DR). Methods A case-control study was conducted. From September 2023 to May 2024, 174 patients with DR and 57 patients with simple age-related cataract were enrolled at […]

A real-world study on related factors of diabetic retinopathy in patients with type 2 diabetes mellitus

Authors:Yang Yingrui, Xu Xun, Sun Jiali, Chen Yanyan, Zhang Mengyue, Huang Zixu, Fan Shuoning, Song Zongming Corresponding authors: Fan Shuoning, Email: fanshuoning@126.com; Song Zongming, Email: szmeyes@126.com Published:2026-09-10 DOI:10.3760/cma.j.cn115989-20251230-00459 ABSTRACT  Objective To explore the correlative factors for diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM), so as to provide evidence for identifying high-risk populations in clinical practice. Methods A single-center, retrospective cross-sectional real-world […]

Analysis of the geometric morphology of macular microvessels in primary open-angle glaucoma based on OCTA

Authors:Fang Zige, Yang Zefeng, Liu Xiaoyi, Xie Bin, Peng Yuying, Liu Yuhong, Liang Xiaohong, Lin Fengbin, Song Yunhe, Zhang Xiulan Corresponding author: Zhang Xiulan,Email:zhangxl2@mail.sysu.edu.cn Published:2026-08-10 DOI:10.3760/cma.j.cn115989-20260212-00077 ABSTRACT  Objective To evaluate alterations in macular microvascular fractal dimension (FD) and blood vessel tortuosity (BVT) in patients with primary open-angle glaucoma (POAG) using optical coherence tomography angiography (OCTA). Methods A […]

Effects of anterior chamber dexamethasone injection on inflammation and visual function in patients with uveitis complicated with cataract and closed pupil membrane

Authors:Yuan Chaofeng, Meng Jia, Shao Jingzhi, Ma Chengxia, Huang Xuetao,Du Liping Corresponding author: Du Liping, Email:1307438431@qq.com Published:2026-08-10 DOI:10.3760/cma.j.cn115989-20260120-00036 ABSTRACT  Objective To explore the effects of intraoperative anterior chamber dexamethasone injection on inflammatory response and visual function in patients with uveitis complicated with cataract and closed pupil membrane. Methods A cohort study was conducted. A total of 76 […]

Dynamic corneal parameter changes and safety in patients with moderate to high risk of corneal ectasia 12 months after SMILE Xtra surgery

Authors:Miao Zhuang, Mo Jing, Lu Qi, Li Qinglan Corresponding author: Mo Jing, Email:mojing@aierchina.com Published:2026-08-10 DOI:10.3760/cma.j.cn115989-20250423-00132 ABSTRACT  Objective To analyze the dynamic changes of multiple corneal parameters and the safety of femtosecond laser small-incision lenticule extraction combined with corneal cross-linking (SMILE Xtra) 12 months postoperatively in patients with moderate-to-high risk of corneal ectasia. Methods A prospective self-control study […]

Clinical characteristics and genotype of a family with Waardenburg syndrome type Ⅰ

Authors:Gu Liang, Gao Fengjie, Guan Huaijin, Ji Min Corresponding author:Ji Min, Email:amyji1234@hotmail.com Published:2026-08-10 DOI:10.3760/cma.j.cn115989-20250303-00063 ABSTRACT  Objective To analyze the clinical and genetic characteristics of a family with Waardenburg syndrome type Ⅰ (WS1) . Methods A pedigree investigation was conducted. Clinical data from 3 generations of 7 people from a family with WS1 in the Nantong area of China, Jiangsu Province, […]

Comparison of 0.5% tropicamide versus 1% tropicamide in cycloplegic optometry in myopic Chinese children: a randomized controlled clinical trial

Authors:Rong Hua, Zhou Yifan, Du Bei, Chong Liuyun, Cai Zhaoying, Liu Ruoxuan, Yu Jingtao, Wei Ruihua Corresponding author:Wei Ruihua, Email:rwei@tmu.edu.cn Published:2026-08-10 DOI:10.3760/cma.j.cn115989-20241226-00364 ABSTRACT  Objective To compare the effects of two dosing regimens, four instillations of 0.5% tropicamide and two instillations of 1% tropicamide, on cycloplegia and ocular biometric parameters in myopic children. Methods A randomized controlled trial was performed. Sixty myopic children (60 eyes) […]

Cone and retinal microvasculature distribution characteristics with idiopathic epiretinal membrane

Authors:Wu Jiang, Ye Xin, Zhou Xiangpeng, He Shucheng, Shen Yingjiao, Shen Lijun Corresponding author:Shen Lijun, Email:slj@mail.eye.ac.cn Published:2026-07-10 DOI:10.3760/cma.j.cn115989-20250613-00200 ABSTRACT  Objective To investigate cone density and retinal microvascular distribution characteristics in idiopathic epiretinal membrane (IERM) by utilizing multimodal imaging techniques. Methods A self-controlled study was conducted. Twenty-eight patients (56 eyes) with unilateral IERM diagnosed at the Department of […]

Imaging and clinical characteristics of combined central retinal artery and vein occlusion

Authors:Xie Ting, Li Zhi, Cheng Xiaorong, Wang Weiqing, Li Jin, Liang Siying, Li Wangting, Chen Qingshan Corresponding author:Chen Qingshan, Email:cqs1967@sina.com Published:2026-07-10 DOI:10.3760/cma.j.cn115989-20240821-00239 ABSTRACT  Objective To analyze the clinical and imaging features of combined central retinal artery and vein occlusion (CCRAVO) and analyze the correlation with visual acuity improvement. Methods An observational case series study was conducted. Fifteen […]

Clinical observation of anti-VEGF therapy for neovascular age-related macular degeneration combined with cataract after surgery

Authors:Wang Qian, Wang Haiyan, Zhang Lei, Ren Yuecong, Yan Hong Corresponding author:Yan Hong, Email:yan2128ts@hotmail.com Published:2026-07-10 DOI:10.3760/cma.j.cn115989-20250120-00017 ABSTRACT  Objective Based on the new classification of macular neovascularization (MNV), to observe the treatment characteristics of anti-vascular endothelial growth factor (VEGF) in patients with neovascular age-related macular degeneration (nAMD) complicated with cataracts after phacoemulsification. Methods A retrospective cohort study was […]