Authors:Zhu Lei, Hao Yiran, Zhao Mengnan, Tian Lei, Jie Ying Corresponding author: Jie Ying, Email:jie_yingcn@aliyun.com Published:2026-10-10 DOI: 10.3760/cma.j.cn115989-20260103-00002 ABSTRACT Objective To evaluate the clinical efficacy of a domestic liquid pulsation technology (LPT) dry eye treatment device combined with cyclosporine A eye drops in treating moderate meibomian gland dysfunction (MGD), and to compare it with conventional meibomian gland expression. Methods A randomized controlled […]
Category: Clinical Science
Comparison of efficacy between platelet-rich plasma and 20% autologous serum in treating refractory corneal epithelial defects
Authors:Zhou Yanrong, Zhao Wenxin, Zhang Ming, Dang Yufei, Li Li Corresponding author: Li Li, Email:eyelili@126.com Published:2026-10-10 DOI: 10.3760/cma.j.cn115989-20260310-00111 ABSTRACT Objective To compare the efficacy of platelet-rich plasma (PRP) versus 20% autologous serum (AS) in treating refractory corneal epithelial defects (RCED). Methods A cohort study was conducted. A total of 50 consecutive patients (50 eyes) with RCED who were treated at the First […]
Correlation and predictive value of IL-6, TGF-β, and IL-17 with corneal graft rejection
Authors:Zhang Yongqian, He Lifen, Wang Jiusan, Xie Yongxian, Cao Qian, Li Lan Corresponding author: Li Lan, Email:641106144@qq.com Published:2026-10-10 DOI:10.3760/cma.j.cn115989-20260306-00095 ABSTRACT Objective To investigate the correlation and predictive value of interleukin (IL)-6, transforming growth factor-β (TGF-β), and IL-17 expression levels in peripheral blood and tears with corneal graft rejection after penetrating keratoplasty (PKP). Methods A cross-sectional study was conducted. A total of 78 […]
Superiority of lacrimal gland long axis in lacrimal gland size evaluation: a high-resolution MRI study in Chinese adults
Authors:Zhou Tianyu, Huang Xiaoyu, Shen Jiachao, Zhong Hongtao, Li Guigang Corresponding author: Li Guigang, Email:guigangli@hust.edu.cn Published:2026-10-10 DOI:10.3760/cma.j.cn115989-20260310-00109 ABSTRACT Objective To establish reference data for lacrimal gland size in Chinese adults using high-resolution magnetic resonance imaging (MRI), and to investigate the correlations between lacrimal gland size and demographic parameters (sex, age, height, weight, and body mass index [BMI]). Methods A cross-sectional study […]
Efficacy of perioperative 0.05% cyclosporine A for dry eye in cataract patients: a randomized controlled clinical trial
Authors:Zhumahan Tuokedaerhan, Wang Yan, Li Xiaolong, Cheng Wanying, Gao Yunxian Corresponding author: Gao Yunxian, Email:gaoyx1973@163.com Published:2026-10-10 DOI:10.3760/cma.j.cn115989-20250602-00179 ABSTRACT Objective To evaluate the efficacy of 0.05% cyclosporine A eye drops for the perioperative treatment of dry eye in patients to undergo cataract surgery. Methods A randomized controlled study was conducted. Sixty patients (60 eyes) with cataract and mild-to-moderate dry eye disease treated […]
Changes in neutrophil-to-lymphocyte ratio in different subtypes of diabetic retinopathy
Authors:Wang Manqiao, Liu Boshi, Li Xiaorong Corresponding author: Li Xiaorong, Email: xiaorli@163.com Published:2026-09-10 DOI: 10.3760/cma.j.cn115989-20260331-00149 ABSTRACT Objective To investigate the changes in the neutrophil-to-lymphocyte ratio (NLR) in different subtypes of diabetic retinopathy (DR). Methods A case-control study was conducted. From September 2023 to May 2024, 174 patients with DR and 57 patients with simple age-related cataract were enrolled at […]
A real-world study on related factors of diabetic retinopathy in patients with type 2 diabetes mellitus
Authors:Yang Yingrui, Xu Xun, Sun Jiali, Chen Yanyan, Zhang Mengyue, Huang Zixu, Fan Shuoning, Song Zongming Corresponding authors: Fan Shuoning, Email: fanshuoning@126.com; Song Zongming, Email: szmeyes@126.com Published:2026-09-10 DOI:10.3760/cma.j.cn115989-20251230-00459 ABSTRACT Objective To explore the correlative factors for diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM), so as to provide evidence for identifying high-risk populations in clinical practice. Methods A single-center, retrospective cross-sectional real-world […]
Analysis of the geometric morphology of macular microvessels in primary open-angle glaucoma based on OCTA
Authors:Fang Zige, Yang Zefeng, Liu Xiaoyi, Xie Bin, Peng Yuying, Liu Yuhong, Liang Xiaohong, Lin Fengbin, Song Yunhe, Zhang Xiulan Corresponding author: Zhang Xiulan,Email:zhangxl2@mail.sysu.edu.cn Published:2026-08-10 DOI:10.3760/cma.j.cn115989-20260212-00077 ABSTRACT Objective To evaluate alterations in macular microvascular fractal dimension (FD) and blood vessel tortuosity (BVT) in patients with primary open-angle glaucoma (POAG) using optical coherence tomography angiography (OCTA). Methods A […]
Effects of anterior chamber dexamethasone injection on inflammation and visual function in patients with uveitis complicated with cataract and closed pupil membrane
Authors:Yuan Chaofeng, Meng Jia, Shao Jingzhi, Ma Chengxia, Huang Xuetao,Du Liping Corresponding author: Du Liping, Email:1307438431@qq.com Published:2026-08-10 DOI:10.3760/cma.j.cn115989-20260120-00036 ABSTRACT Objective To explore the effects of intraoperative anterior chamber dexamethasone injection on inflammatory response and visual function in patients with uveitis complicated with cataract and closed pupil membrane. Methods A cohort study was conducted. A total of 76 […]
Dynamic corneal parameter changes and safety in patients with moderate to high risk of corneal ectasia 12 months after SMILE Xtra surgery
Authors:Miao Zhuang, Mo Jing, Lu Qi, Li Qinglan Corresponding author: Mo Jing, Email:mojing@aierchina.com Published:2026-08-10 DOI:10.3760/cma.j.cn115989-20250423-00132 ABSTRACT Objective To analyze the dynamic changes of multiple corneal parameters and the safety of femtosecond laser small-incision lenticule extraction combined with corneal cross-linking (SMILE Xtra) 12 months postoperatively in patients with moderate-to-high risk of corneal ectasia. Methods A prospective self-control study […]