Category: Clinical Science

Changes of serum complement factors in patients with diabetic retinopathy

Authors: Sun Hongyan,  Ma Ruirui,  Chen Jiayu,  Yu Xuhui,  Yang Mingming DOI: 10.3760/cma.j.cn115989-2019051-00212 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 754-759. Abstract Objective To detect the changes of serum complement factors C3 and C4 in diabetic retinopathy (DR) patients, and to explore their role in the occurrence and development of DR. Methods A […]

Changes of brain function in resting-state in patients with nonproliferative diabetic retinopathy assessed by fractional low-frequency amplitude technique

Authors: Qi Chenxing,  Huang Xin,  Tong Yan,  Shen Yin DOI: 10.3760/cma.j.cn115989-20190920-00406 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 760-765. Abstract Objective To study the changes of brain function in patients with diabetic retinopathy (DR) by using resting-state functional magnetic resonance imaging (rs-fMRI) based on the fractional amplitude of low-frequency fluctuation (fALFF) method. Methods […]

Relationship between degree of diabetic retinopathy and changes of corneal sub-basal nerve plexus in the whorl-like region

Authors: Yu Hua,  Miao Yingbin,  Zhao Shaozhen,  Yang Jizhong,  Zheng Xiaofen,  Han Yuping, Zhao Juwei DOI: 10.3760/cma.j.cn115989-2019-0618-00269 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 767-772. Abstract Objective To estimate the correlation between DR and diabetic corneal nerve damage by comparing changes of corneal sub-basal nerve plexus (SNP) in the whorl-like region in different […]

A Meta-analysis of the effects of intravitreal conbercept as an adjunct before vitrectomy in proliferative diabetic retinopathy

Authors: Si Xia,  Sun Chufeng,  Chen Yue,  Feng Wanyu,  Feng Yufei DOI: 10.3760/cma.j.cn115989-20200715-00498 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 773-780. Abstract Objective To evaluate the efficacy and safety of preoperative intravitreal conbercept (IVC) as an adjunct to pars plana vitrectomy (PPV) in the treatment of proliferative diabetic retinopathy (PDR). Methods A systematic […]

Changes of macular vessel density and structures in different early stages of diabetic retinopathy

Authors: Zeng Yunkao,  Yang Dawei,  Cao Dan,  Yu Honghua,  Lu Manhong,  Zhuang Xuenan,  Zhang Liang DOI: 10.3760/cma.j.cn115989-20200715-00497 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 783-787. Abstract Objective To investigate the characteristics of macular perfusion and structures in patients with early stages of diabetic retinopathy (DR) using optical coherence tomography angiography (OCTA). Methods A […]

Choroidal thickness in severe congenital ptosis with amblyopia

Authors: Zhang Weiwei,  Ren Xiaoxia,  Xie Juan,  Wang Jingjing,  Tang Dongrun,  Sun Fengyuan,  Wu Tong DOI: 10.3760/cma.j.cn115989-20200507-00314 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 788-794. Abstract Objective To measure the choroidal thickness (CT) in the macular area of patients with amblyopia in severe congenital ptosis and to compare the thickness with that of severe […]

Association of TLR4 polymorphisms with primary open angle glaucoma in Chinese population

Authors: Shu Yi,  Xu Jiaxin,  Yang Chen,  Chen Yilian,  Luo Qian,  Gong Bo,  Yang Zhenglin,  Huang Guo DOI: 10.3760/cma.j.cn115989-20191120-00505 Published 2020-08-10 Cite as Chin J Exp Ophthalmol, 2020,38(08): 659-664. Abstract Objective To detect whether Toll-like receptor 4 (TLR4) polymorphisms contributed to primary open angle glaucoma (POAG) in a Chinese population. Methods A Chinese cohort, including 799 […]

Association study of single nucleotide polymorphism of rs284489 in the 8q22 region with primary open angle glaucoma in a Sichuan Han Chinese population

Authors: Xu Siyao,  Liu Xiaoqi,  Lin Ying,  Gong Bo,  Yang Zhenglin DOI: 10.3760/cma.j.cn115989-20200509-00321 Published 2020-08-10 Cite as Chin J Exp Ophthalmol, 2020,38(08): 665-669. Abstract Objective To investigate the association between rs284489 in the 8q22 region and primary open angle glaucoma (POAG) in Sichuan, and the association between rs284489 and gender difference. Methods A case control study […]

TTR mutations and clinical characteristics of vitreous amyloidosis patients

Authors: Zhang Xiaohui,  Xu Ke,  Xu Xiaolin,  Xie Yue,  Li Yang DOI: 10.3760/cma.j.cn115989-20190419-00192 Published 2020-08-10 Cite as Chin J Exp Ophthalmol, 2020,38(08): 670-674. Abstract Objective To investigate the transthyretin (TTR) mutations and clinical characteristics of patients with vitreous amyloidosis. Methods Ten cases of suspected vitreous amyloidosis were recruited in Beijing Tongren Hospital from January 2011 to […]

Genotype and clinical phenotype analysis of a five-generation Ningxia family with autosomal dominant retinitis pigmentosa pedigree

Authors: Rong Weining,  Zhang Fangxia,  Liu Yani,  Lei Bo,  Sheng Xunlun DOI: 10.3760/cma.j.cn115989-20190212-00050 Published 2020-08-10 Cite as Chin J Exp Ophthalmol, 2020,38(08): 675-679. Abstract Objective To identify the pathogenic mutation in a five-generation Ningxia family with autosomal dominant retinitis pigmentsoa (adRP) and to analyze its associated clinical phenotype. Methods One adRP pedigree was recruited for this […]