Research progress for filtering blebs leakage after anti-glaucoma surgery

Recent researches showed the incidence of filtering blebs leakage after anti-glaucoma surgery was 3%-25%.The affecting factors include the usage of antimetabolite medicine.Pathogenesis of filtering blebs leakage is the basement membrane of conjunctival cells fracture, reduced conjunctival cells and subconjunctival cells.It may cause hypotony, bleb infection and even endoophthalmitis.The treatments mainly include conservative therapy and surgery.Conservative therapy methods include package, autoserum or fibrin injection or eye drops and tissue glue.Surgery methods include conjunctival transposition, repair with conjunctival, corneal, scleral, amniotic membrane and biomechanical materials.Filtering blebs leakage may induce severve complications without timely treatments.Conservative therapy and surgery have their own limitations, which need to be considered intently and followed up closely.