Research progress on the effect of orthokeratology lens on ocular surface microenvironment

Orthokeratology lens is an optical correction method mainly used to control the development of myopia in children and adolescents.In recent years, the material and parameter design of orthokeratology lens has been constantly updated and improved.Despite its customizable, well-permeable, and optically superior properties, the ocular surface microenvironment may be affected by multiple factors after a long-term lens wear, resulting in a homeostatic imbalance of the ocular surface microenvironment due to direct attachment of the lens to the ocular surface.As the incidence of myopia in children and adolescents has increased rapidly in recent years, orthokeratology lens has been widely used as a non-surgical treatment to control the refractive growth of myopia.Understanding the influence of long-term orthokeratology lens wear on the ocular surface microenvironment can help avoid the related risk in myopia prevention and control.Therefore, this paper summarizes the effects of orthokeratology lens wear on ocular surface tissues, cells, tear fluid and microbiota, focuses on the potential risks of long-term orthokeratology lens wear, and leads optometrists to give comprehensive consideration to improving safety and effectiveness during the eyesight testing and follow-up.

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