Category: Highlights

Paying attention to the application of proteomics and metabolomics in clinical and translational research of diabetic retinopathy

Authors: Zhang Hui,  Li Xiaorong,  Zhou Lei DOI: 10.3760/cma.j.cn115989-20220831-00406 Published 2022-09-10 Cite asChin J Exp Ophthalmol, 2022, 40(9): 791-795. Abstract Diabetic retinopathy (DR) is one of the complications of diabetic mellitus and a major cause of blindness worldwide.Early detection and treatment for DR could reduce the risk of blindness.With the development of high-throughput omics, proteomics […]

Protective effect of tert-butylhydroquinone on retinal morphology and function in early diabetic rats and its mechanism

Authors: Wang Juan,  Wei Fang,  Cao Yang,  Tian Min,  Lyu Hongbin DOI: 10.3760/cma.j.cn115989-20191225-00555 Published 2022-09-10 Cite asChin J Exp Ophthalmol, 2022, 40(9): 796-803. Abstract Objective To investigate the protective effects of an antioxidant tert-butylhydroquinone (tBHQ) on the morphology and function of retina in early-stage experimental diabetic rats, and to explore the mechanism of its protective […]

Inhibitory effect of microRNA-23b-3p on high glucose-induced autophagy and apoptosis of human lens epithelial cells and its mechanism

Authors: Liu Wenlan,  Wang Li,  Yang Yang,  Yan Jin,  He Yuan DOI: 10.3760/cma.j.cn115989-20210309-00154 Published 2022-09-10 Cite asChin J Exp Ophthalmol, 2022, 40(9): 804-812. Abstract Objective To investigate the regulatory effects of microRNA-23b-3p (miR-23b-3p) on the autophagy and apoptosis of human lens epithelial cells induced by high glucose. Methods Thirty diabetic cataract (DC) patients as DC […]

Network pharmacology analysis of ginkgo leaves extract against diabetic retinopathy

Authors: Bai Wen,  Jiang Qin DOI: 10.3760/cma.j.cn115989-20210105-00010 Published 2022-09-10 Cite asChin J Exp Ophthalmol, 2022, 40(9): 813-819. Abstract Objective To explore the key targets of ginkgo leaves extract against diabetic retinopathy (DR), and the underlying pharmacological mechanism by network pharmacology. Methods Potential targets of active components in ginkgo folium were searched from the Traditional Chinese […]

Meibomian gland dysfunction and expressions of inflammatory factors and lipid metabolic factors in diabetic mice

Authors: Zou Yuanyuan,  Liu Xuemei,  Qi Yuanyuan,  Zhao Shaozhen DOI: 10.3760/cma.j.cn115989-20210207-00098 Published 2022-09-10 Cite asChin J Exp Ophthalmol, 2022, 40(9): 820-826. Abstract Objective To explore the changes in morphology and function of meibomian gland and the expressions of inflammatory factors and lipid metabolic factors in meibomian gland of diabetic mice. Methods Fifty 8-week-old male C57BL/6 […]

Changes of subfoveal choroidal thickness and choroidal volume in different stages of diabetic retinopathy through automated choroid segmentation

Authors: Fan Wen,  Chen Qiang,  Ge Weizhong,  Liu Qinghuai,  Yuan Songtao DOI: 10.3760/cma.j.cn115989-20200630-00465 Published 2022-09-10 Cite asChin J Exp Ophthalmol, 2022, 40(9): 827-831. Abstract Objective To analyze the changes of subfoveal choroidal thickness (SFCT) and choroidal volume in type 2 diabetes patients with diabetic retinopathy (DR) through automated choroid segmentation. Methods A cross-sectional study was […]

Comparison of macular and choroidal capillary vessel density between untreated CSC and PCV and its significance

Authors: Yin Xinkai,  Dai Rongping DOI: 10.3760/cma.j.cn115989-20211111-00623 Published 2022-09-10 Cite asChin J Exp Ophthalmol, 2022, 40(9): 832-840. Abstract Objective To quantitatively assess the macular and choroidal capillary vessel density and foveal avascular zone (FAZ) variables in untreated central serous chorioretinopathy (CSC), polypoidal choroidal vasculopathy (PCV) patients and healthy people using optical coherence tomography angiography (OCTA), […]

Multicolor scanning laser imaging in macular telangiectasia

Authors: Meng Xiangjuan,  Xie Xiao,  Guan Jitian,  Wang Jinyan,  Sun Xiaolei,  Wang Hongyan,  Meng Jie,  Wang Ying,  Liu Tingting DOI: 10.3760/cma.j.cn115989-20191210-00536 Published 2022-09-10 Cite asChin J Exp Ophthalmol, 2022, 40(9): 841-846. Abstract Objective To observe the characteristics of macular telangiectasia (MacTel) in multi-color and multi-mode fundus images. Methods An abservational case series study was conducted.Sixteen […]

Features of iris and fundus fluorescein angiography in diabetic iridopathy

Authors: Li Shiqing,  Wang Zhili,  Chen Xiao,  Li Xiaohua DOI: 10.3760/cma.j.cn115989-20210218-00115 Published 2022-09-10 Cite asChin J Exp Ophthalmol, 2022, 40(9): 847-851. Abstract Objective To investigate the imaging features of iris fluorescein angiography (IFA) combined with fluorescein fundus angiography (FFA) in diabetic iridopathy. Methods A cross-sectional study was conducted.Sixty-five eyes of 44 patients with proliferative diabetic […]

Prevalence of mild visual impairment in type 2 diabetes patients over 50 years old in Funing County: Jiangsu Diabetic Eye Disease Study

Authors: Wang Shiyi,  Yang Mei,  Liu Bihong,  Sun Dajun,  Liang Congkai,  Shen Yaqin,  Zhu Rongrong DOI: 10.3760/cma.j.cn115989-20200801-00551 Published 2022-09-10 Cite asChin J Exp Ophthalmol, 2022, 40(9): 852-858. Abstract Objective To investigate the prevalence and influencing factors of mild visual impairment in type 2 diabetic patients aged ≥50 years living in Funing County, Jiangsu Province. Methods […]