Advances of muscarinic antagonists slowing the progression of myopia

The myopic population is growing rapidly worldwide, the treatment of myopia become one of the hot spots in ophthalmology.Medicine therapy of myopia is now commonly used to slow down the progression of myopia, and it has already been the most expected one.Among all the drugs, the effect of muscarinic antagonists has been recognized at home and abroad.Muscarinic antagonists, according to their different M receptors, own different interventional approaches and therapeutic effects.Muscarinic antagonists, such include atropine, pirenzepine, tropicamide and cyclopentolate, their pharmacology and adverse effects are analyzed in order to explore their safety and efficacy and evaluate their clinical value.This paper reviewed these aspects of muscarinic antagonists and raise the discussion and prospect of muscarinic antagonists in the treatment of myopia.