Authors: Long Wenxiu, Yang Lihong, Xu Jie, He Shengyu, Li Shaowei, Wang Congxiang, Wang Kehua, Ran Ruqiu, Tang Jian
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This study was to evaluate the safety of 640 corneal donors by analysing the serological testing results.
We retrospectively analyzed the serological testing results from Changsha Aier Eye Bank and Chengdu Kangqiao Aier Eye Bank from January 2011 to December 2015, hepatitis B virus surface antigen (HBsAg), hepatitis C virus (HCV), treponema pallidum (TP) and human immunodeficiency virus (HIV) were detected by colloidal gold or enzyme-linked immunosorbent assay (ELISA).
There were 83 out of 640 serum samples showed positive immuno-reaction assayed markers, the positive rate was 12.97%, including HBsAg(n=60, 9.38%), HCV(n=3, 0.47%), TP(n=11, 1.72%) and HIV(n=2, 0.31%). Moreover, 3 corneal donors were both positive against HBsAg and HCV, 2 donors positive against HCV and TP, 1 donor positive against HBsAg and HIV, 1 donor positive against HBsAg and TP.
There is a high proportion of positive results of blood-borne diseases in cornea donors, which is a potential threat to corneal receptors and eye bank workers.Therefore, it is very important to detect serological test strictly for corneal donors.