Analysis of the serological testing results from Aier Eye Bank

Authors: Long Wenxiu,  Yang Lihong,  Xu Jie,  He Shengyu,  Li Shaowei,  Wang Congxiang,  Wang Kehua,  Ran Ruqiu,  Tang Jian

DOI: 10.3760/cma.j.issn.2095-0160.2018.05.006
Published 2018-05-10
Cite as Chin J Exp Ophthalmol, 2018,36(5): 351-354.

Abstract

Objective

This study was to evaluate the safety of 640 corneal donors by analysing the serological testing results.

Methods

We retrospectively analyzed the serological testing results from Changsha Aier Eye Bank and Chengdu Kangqiao Aier Eye Bank from January 2011 to December 2015, hepatitis B virus surface antigen (HBsAg), hepatitis C virus (HCV), treponema pallidum (TP) and human immunodeficiency virus (HIV) were detected by colloidal gold or enzyme-linked immunosorbent assay (ELISA).

Results

There were 83 out of 640 serum samples showed positive immuno-reaction assayed markers, the positive rate was 12.97%, including HBsAg(n=60, 9.38%), HCV(n=3, 0.47%), TP(n=11, 1.72%) and HIV(n=2, 0.31%). Moreover, 3 corneal donors were both positive against HBsAg and HCV, 2 donors positive against HCV and TP, 1 donor positive against HBsAg and HIV, 1 donor positive against HBsAg and TP.

Conclusions

There is a high proportion of positive results of blood-borne diseases in cornea donors, which is a potential threat to corneal receptors and eye bank workers.Therefore, it is very important to detect serological test strictly for corneal donors.

Key words:

Corneal donors; Serological testing; Hepatitis B virus surface antigen; Safety

Contributor Information

Long Wenxiu
Aier School of Ophthalmology, Central South University, Changsha 410015, China; Changsha Aier Eye Hospital, Changsha 410015, China
Yang Lihong
Changsha Aier Eye Hospital, Changsha 410015, China
Xu Jie
Chengdu Cambridge Eye Hospital, Chengdu 610041, China
He Shengyu
Aier School of Ophthalmology, Central South University, Changsha 410015, China
Li Shaowei
Beijing Aier Intech Eye Hospital, Beijing 100021, China
Wang Congxiang
Changsha Aier Eye Hospital, Changsha 410015, China
Wang Kehua
Changsha Aier Eye Hospital, Changsha 410015, China
Ran Ruqiu
Chengdu Cambridge Eye Hospital, Chengdu 610041, China
Tang Jian
Chengdu Cambridge Eye Hospital, Chengdu 610041, China
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