Authors:Wang Qing, Zhuang Tongtong, Dong Lijie,Wang Linni Corresponding author:Wang Linni, Email:wln5156@163.com Published:2026-07-10 DOI:10.3760/cma.j.cn115989-20250609-00190 ABSTRACT Objective To observe the effect and possible mechanism of interleukin (IL)-8 antagonist SB225002 on the activation of nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome in monkey retinal vascular endothelial cells (RF/6A cells) under high glucose conditions. Methods The RF/6A cells cultured in vitro were […]
Category: Experimental Science
Preventive and protective effects of guanethidine against MRSA endophthalmitis in rabbits
Authors:Liang Qian, Shao Zheng,Fan Zheng, Wang Weina, Huang Yusen Corresponding author:Huang Yusen, Email:huang_yusen@126.com Published:2026-07-10 DOI:10.3760/cma.j.cn115989-20240612-00150 ABSTRACT Objective To establish a rabbit model of methicillin-resistant Staphylococcus aureus (MRSA) endophthalmitis and to investigate the regulatory effects of the sympatholytic agent guanethidine on the inflammatory response in endophthalmitis. Methods Six male New Zealand white rabbits of about 2.5 kg were selected and […]
Effect of miR-655-3p targeting FOXC1 and CXCR4 on angiogenesis in hypoxic human umbilical vein endothelial cells
Authors: Yang Lingqi, Li Jianfeng, Yang Hongxia, Wang Xue, Lyu Yang Published: 2026 -06 -10 DOI: 10.3760/cma.j.cn115989-20240715-00194 Citation Yang Lingqi, Li Jianfeng, Yang Hongxia, et al. Effect of miR-655-3p targeting FOXC1 and CXCR4 on angiogenesis in hypoxic human umbilical vein endothelial cells[J]. Chin J Exp Ophthalmol, 2026, 44(6):521-530. DOI: 10.3760/cma.j.cn115989-20240715-00194. ABSTRACT […]
In vitro study on corneal biomechanical changes after corneal stromal lenticule implantation combined with corneal collagen cross-linking
Authors: Shen Di, Zhang Na, Sun Xiyu, Wei Wei DOI: 10.3760/cma.j.cn115989-20260121-00038 Published: 2026 -05 -10 Citation Shen Di, Zhang Na, Sun Xiyu, et al . In vitro study on corneal biomechanical changes after corneal stromal lenticule implantation combined with corneal collagen cross-linking[J]. Chin J Exp Ophthalmol, 2026, 44(5):439-446. DOI: 10.3760/cma.j.cn115989-20260121-00038. ABSTRACT […]
Effect of high-fat diet on refractive development and ocular biological characteristics in guinea pigs
Authors: Zhang Xiaoran, Chen Yamin, Zhang Ning, Luan Zichen, Hao Rui DOI: 10.3760/cma.j.cn115989-20250901-00283 Published: 2026 -04 -10 Citation Zhang Xiaoran, Chen Yamin, Zhang Ning, et al. Effect of high-fat diet on refractive development and ocular biological characteristics in guinea pigs[J]. Chin J Exp Ophthalmol, 2026, 44(4):331-338. DOI: 10.3760/cma.j.cn115989-20250901-00283. ABSTRACT [Download […]
Construction of a mouse defocus myopia model based on an anti-scratch device and changes in ocular OCT parameters
Authors: Qin Zhuozhen, Fang Yan, Xie Chi, Zhu Shaojin, Ding Liang, Pan Zhongcen DOI: 10.3760/cma.j.cn115989-20250408-00113 Published: 2026 -04 -10 Citation Qin Zhuozhen, Fang Yan, Xie Chi, et al. Construction of a mouse defocus myopia model based on an anti-scratch device and changes in ocular OCT parameters[J]. Chin J Exp Ophthalmol, 2026, 44(4):339-345. DOI: 10.3760/cma.j.cn115989-20250408-00113. ABSTRACT […]
Role of YAP1 in regulating lens epithelial cell proliferation and cell cycle by binding to the SOX2 promoter
Authors: Chen Fei, Ma Jingyu, Yu Wenlu, Luo Lixia, Tan Xuhua DOI: 10.3760/cma.j.cn115989-20260104-00005 Published: 2026 -03 -10 Citation Chen Fei, Ma Jingyu, Yu Wenlu, et al.Role of YAP1 in regulating lens epithelial cell proliferation and cell cycle by binding to the SOX2 promoter[J]. Chin J Exp Ophthalmol, 2026, 44(3):209-217. DOI: 10.3760/cma.j.cn115989-20260104-00005. ABSTRACT […]
Inhibitory effect of stachydrine on high glucose-induced apoptosis in human lens epithelial cells and its mechanism
Authors: Wu Guijia, Chen Xiteng, Kou Zhenyu, Gao Nan, Bai Xiaomei, Mao Han, Jiang Yuanfeng, Dong Lijie, Tian Fang DOI: 10.3760/cma.j.cn115989-20240722-00204 Published: 2026 -03 -10 Citation Wu Guijia, Chen Xiteng, Kou Zhenyu, et al. Inhibitory effect of stachydrine on high glucose-induced apoptosis in human lens epithelial cells and its mechanism[J]. Chin J Exp Ophthalmol, 2026, 44(3):218-226. DOI: 10.3760/cma.j.cn115989-20240722-00204. […]
Imaging quality and anti-eccentricity performance of axial modulation aspherical intraocular lens in model eyes
Authors: Zhang Bin, Ren Taoran, Wu Jiahui, Li Minhao, Liu Danyan, Liu Xiaoli, Geng Yuxin DOI: 10.3760/cma.j.cn115989-20240531-00139 Published: 2026 -03 -10 Citation Zhang Bin, Ren Taoran, Wu Jiahui, et al. Imaging quality and anti-eccentricity performance of axial modulation aspherical intraocular lens in model eyes[J]. Chin J Exp Ophthalmol, 2026, 44(3):227-231. DOI: 10.3760/cma.j.cn115989-20240531-00139. ABSTRACT […]
Development and validation of a rapid detection method for HSV or VZV in intraocular fluid based on a single-tube MIRA-CRISPR/Cas12a system
Authors: Xue Zhijia, Qian Sheng, Li Xirui, Li Suyan, Qiao Lei Published： 2026 -02 -10 DOI: 10.3760/cma.j.cn115989-20250421-00130 Citation Xue Zhijia, Qian Sheng, Li Xirui, et al. Development and validation of a rapid detection method for HSV or VZV in intraocular fluid based on a single-tube MIRA-CRISPR/Cas12a system[J]. Chin J Exp Ophthalmol, 2026, 44(2):112-120. DOI: 10.3760/cma.j.cn115989-20250421-00130. ABSTRACT […]