Category: Experimental Science

Fibrillin-2 interfering induced retinopathy and its possible mechanism

Authors: Zhang Ruixue, Jiang Wenjun, Guo Dadong, Shi Yongwei, Bi Hongsheng, Wen Ying DOI: 10.3760/cma.j.cn115989-20231014-00130 Published: 2024 -09 -10 Citation: Zhang Ruixue, Jiang Wenjun, Guo Dadong, et al. Fibrillin-2 interfering induced retinopathy and its possible mechanism[J]. Chin J Exp Ophthalmol ,2024,42(9):798-805. DOI: 10.3760/cma.j.cn115989-20231014-00130. ABSTRACT      [Download PDF] [Read Full Text]  Objective  To investigate the expression of latent […]

Inhibitory effect of knocking down LOXL1 gene on elastin expression and cell biological behavior in HLECs

Authors: Dong Yue, Ma Yinu, Yi Xianglong DOI: 10.3760/cma.j.cn115989-20230911-00095 Published: 2024 -09 -10 Citation: Dong Y, Ma YN, Yi XL. Inhibitory effect of knocking down LOXL1 gene on elastin expression and cell biological behavior in HLECs[J]. Chin J Exp Ophthalmol ,2024,42(9):807-813. DOI: 10.3760/cma.j.cn115989-20230911-00095. ABSTRACT      [Download PDF] [Read Full Text]  Objective  To investigate the effect of knocking […]

Correlation analysis between early visual function impairment and neuron function abnormality in diabetic mouse primary visual cortex

Authors: Tang Haoqiong,  Feng Lixia,  Tao Tianchang,  Zeng Yige DOI: 10.3760/cma.j.cn115989-20231017-00137 Published 2024-08-10 Cite as Chin J Exp Ophthalmol, 2024, 42(8): 698-704. Abstract                                       [Download PDF] [Read Full Text] Objective To investigate the damage of visual function in the […]

Inhibitory effect of ferulic acid on the retina of diabetic mice and high glucose-induced human retinal pigment epithelium cell injury and the mechanism

Authors: Zhu Dejun,  Zou Wenqing,  Cao Xiangmei,  Wang Xiaofei,  Lu Zhaogang DOI: 10.3760/cma.j.cn115989-20231114-00173 Published 2024-08-10 Cite as Chin J Exp Ophthalmol, 2024, 42(8): 705-715. Abstract                                        [Download PDF] [Read Full Text] Objective To investigate the inhibitory effect of […]

Pathogenic role and mechanism of NADPH oxidase 4 in type 1 diabetic keratopathy mouse

Authors: Zhao Wenxin,  Zhang Xian,  Qin Yazhou,  Zhang Ming,  Gao Ning,  Qin Li,  Li Jingming DOI: 10.3760/cma.j.cn115989-20200320-00188 Published 2024-07-10 Cite as Chin J Exp Ophthalmol, 2024, 42(7): 602-612. Abstract                             【Download PDF】【Read Full Text】 Objective To investigate the pathogenic role and possible mechanism of […]

Ocular safety of intravitreal injection of a novel nanoparticle ciliary neurotrophic factor complex in cynomolgus macaques——a morphological evaluation

Authors: Zhang Tianlu,  Liu Yifan,  Shen Yin DOI: 10.3760/cma.j.cn115989-20220212-00052 Published 2024-07-10 Cite as Chin J Exp Ophthalmol, 2024, 42(7): 613-620. Abstract                             【Download PDF】【Read Full Text】 Objective To evaluate the safety of a novel nanoparticle neurotrophic factor complex for intraocular application in non-human primates. […]

Comparison of the pharmacokinetics of gatifloxacin ophthalmic gel in rabbit ocular tissues with different dosing frequencies

Authors: Wang Xiaotong,  Zhao Xin,  Zu Wei,  Shen Xu,  Chen Shichao,  Yang Qiang DOI: 10.3760/cma.j.cn115989-20220513-00215 Published 2024-07-10 Cite as Chin J Exp Ophthalmol, 2024, 42(7): 621-628. Abstract                            【Download PDF】【Read Full Text】 Objective To establish a method for determining the concentration of gatifloxacin in […]

Efficacy and safety of HA-Mg drainage plate implantation in anterior chamber for intraocular pressure control in rabbit eyes

Authors: Zhu Xiaomin,  Luo Wangdu,  Lin Yi,  Cai Mingming,  Chen Yi,  Xie Lin,  Wang Yong,  Li Xiangji DOI: 10.3760/cma.j.cn115989-20230301-00071 Published 2024-06-10 Cite as Chin J Exp Ophthalmol, 2024, 42(6): 503-510. Abstract                               [Download PDF] [Read Full Text] Objective To evaluate the safety and […]

Proteomic analysis of aqueous humor in patients with exfoliation syndrome

Authors: Xu Zhao,  Wang Liming,  Feng Qiang,  Zhang Dandan,  Ayiguzaili Tuerdimaimaiti,  Guo Ruru,  Dong Lijie,  Wei Ruihua,  Liu Aihua DOI: 10.3760/cma.j.cn115989-20221101-00509 Published 2024-06-10 Cite as Chin J Exp Ophthalmol, 2024, 42(6): 512-519. Abstract                               [Download PDF] [Read Full Text] Objective To analyze the […]

MeCP2-induced alterations of transcriptome and m6A modification in retinal pigment epithelial cell

Authors: Zhang Yongya,  Li Xiaohua,  Zhao Xueru,  Li Xue DOI: 10.3760/cma.j.cn115989-20230920-00105 Published 2024-05-10 Cite as Chin J Exp Ophthalmol, 2024, 42(5): 408-416. Abstract                              [Download PDF] [Read Full Text] Objective To investigate mRNA and N6-methyladenosine (m6A) changes in retinal pigment epithelium (RPE) cells […]