Application of ischemic index of ultra-widefield fluorescein angiography in retinal vascular diseases

Authors: Jiang Jingwen,  Chen Changzheng
DOI: 10.3760/cma.j.cn115989-20190422-00194
Published 2022-11-10
Cite asChin J Exp Ophthalmol, 2022, 40(11): 1100-1103.

Abstract                              [View PDF] [Read Full Text]

Fluorescein fundus angiography (FFA) is an important examination to observe retinal vascular diseases, but the observation of peripheral retina is limited through traditional FFA.Ultra-widefield fluorescein angiography (UWFA) is a new technique which helps to expand the field of view in retina, and explores peripheral retinopathy clearly.To accurately quantify the retinal non-perfusion area, ischemic index (ISI) was proposed.It is calculated by the ratio of the retinal non-perfusion area to the total retinal area by manual description of non-perfusion area in UWFA images.As a reliable index for evaluating retinal ischemia, it is of great significance to study ISI in the classification, treatment and prognosis of retinal vascular diseases such as diabetic retinopathy (DR) and retinal vein occlusion (RVO). This article reviewed the progress in application and development of ISI in retinal vascular diseases.

Key words:

Fluorescein angiography; Diabetic retinopathy; Retinal vein occlusion; Ischemic index; Review

Contributor Information

Jiang Jingwen

Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430060, China

Chen Changzheng

Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430060, China

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