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Positron emission tomography and computed tomography (PET/CT) fusion combines the advantages of both imaging modalities (quantification of metabolic activity and anatomic localization of tumor). With once scan, whole-body imagings can obtain with highly sensitivity to reflect the physiological and biochemical processes of the body and accurate position about the lesions. As an important clinical imaging diagnostic tool, since the first combined PET/CT scanner introduced to the medical community in 1998, it’s has been gradually applied in the detection of ophthalmic tumors in recent years, such as choroidal melanoma, choroidal metastatic carcinoma, retinoblastoma, ocular lymphoma, adenoid cystic carcinoma of lacrimal gland etc. In this paper, the principle of PET/CT, the clinical application value of standardized uptake value (SUV) and the clinical application of PET/CT in ocular tumors were summarized.