Application of the swept-source coherence tomography biometer in measurement for cataractous eyes with high myopia

Objective

To evaluate measurement acquisition, operability, and measurement agreement of the OA-2000 in cataract eyes with high myopia.

Methods

A diagnosis test examined 1 030 eyes of 780 high-myopia cataract patients at the Wuhan Aier Eye Hospital from October 2017 to October 2018.The eyes were examined using the OA-2000, the IOLMaster 500 and the Lenstar-LS900 preoperatively.Measurement acquisition was recorded.The total ophthalmic exam, the duration of patient data entry, the actual measurement process, and the time from intraocular lens power calculation to printout were calculated.Ocular biometric parameters, including anterior chamber depth (ACD), axial length (AL), keratometry for the flattest meridian (Kf), and keratometry for the steepest meridian (Ks) were compared among the devices.This study complied with the Declaration of Helsinki.The study protocol was approved by the Ethics Committee of Wuhan Aier Eye Hospital (No.2017IRBKY07).

Results

The OA-2000 was capable of obtaining an AL measurement in 94.95% of the eyes, which was significantly higher than the 83.98% and 83.01% measured by the IOLMaster 500 and Lenstar-LS900, respectively (χ²=38.171, 46.208; both at P<0.001). The total ophthalmic exam with the OA-2000 took a significantly shorter time than the Lenstar-LS900 ([109.34±2.22]s vs. [135.64±5.55]s) (P<0.05). Excellent correlations were found for the AL, ACD, Kf, and Ks measurements between the OA-2000 and the IOLMaster 500 (r=0.999, 0.937, 0.996, 0.996; all at P<0.001). Good correlations were also found between the OA-2000 and the Lenstar-LS900 (r=0.999, 0.965, 0.995, 0.996; all at P<0.001). The respective 95% limits of agreement of the OA-2000 and IOLMaster 500, and the OA-2000 and Lenstar-LS900 were -0.19 to 0.20 mm and -0.13 to 0.17 mm for AL; -0.23 to 0.23 mm and -0.18 to 0.16 mm for ACD; -0.48 to 0.47 D and -0.64 to 0.65 D for Kf; -0.49 to 0.47 D and -0.60 to 0.61 D for Ks.

Conclusions

In terms of AL, ACD, Kf and Ks in cataractous eyes with high myopia, the OA-2000, IOLMaster 500, and Lenstar-LS900 show excellent correlation and agreement.The OA-2000, a new swept-source OCT-based biometer, outperforms both the IOLMaster 500 and the Lenstar-LS900 in terms of AL measurement acquisition and operability.