Application of zebrafish in ophthalmology and vision research: history and current progress

Authors: Chen Xueli,  Jing Yang,  Zhang Qi
DOI: 10.3760/cma.j.issn.2095-0160.2016.04.017
Published 2016-04-10
Cite as Chin J Exp Ophthalmol, 2016,34(4): 368-370.

Abstract                            [Download PDF] [Read Full Text]

In recent years, zebrafish has become ideal animal models of human disease with its unique characteristics, such as small body, fecundity, fast development and growth, embryo transparency, and so on.Furthermore, the structure and gene of zebrafish eye are highly conservative with human eye, which make ophthalmologists to pay close attentions to zebrafish.This review focused on the studies and applications on zebrafish embryonic development of eyes, and also the applications of currently used genetic regulation and editing techniques and tools.

Key words:

Zebrafish; Model, animal; Eye; Genetics

Contributor Information

Chen Xueli
Ocular Genomic Institute, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA (Chen XL, now Department of Ophthalmology and Vision Science, Shanghai Medical College, Eye and Ear Nose Throat Hospital, Fudan University, Shanghai 200031, China)
Jing Yang
Zhang Qi
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