Category: Clinical Science

Efficacy evaluation of intravitreal injection of rAAV2-ND4 gene for Leber hereditary optic neuropathy

·Clinical Research· Evaluation of the efficacy of rAAV2-ND4 intravitreal injection for Leber’s hereditary optic neuropathy  Li Xin1, Tian Zhen1, Chen Zhang 1,  Li Bin1 ,2 ,3, Zhang Yong 1 1Department of Ophthalmology, Shiyan Taihe Hospital, Affiliated Hospital of Hubei University of Medicine, Shiyan 442000, China; 2Department of Ophthalmology, Tongji Hospital, Tongji Medical College of Huazhong […]

Association between LIPC gene rs10468017 polymorphism and the susceptibility to age-related macular degeneration: a Meta-analysis

Authors: Gu Hong,  Xu Zhangxing,  Shen Zhaomeng,  Li Zhiguo DOI: 10.3760/cma.j.cn115989-20191117-00498 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 729-736. Abstract                              [View PDF] [Read Full Text] Objective To systematically evaluate the association between the hepatic lipase (LIPC) gene rs10468017 polymorphism and susceptibility to age-related […]

Peripheral retinal fluorescence features of ultra-wide fundus fluorescein angiography in normal fundus eyes

Authors: Wang Xiaoling,  Chen Changzheng,  Xu Amin,  Yi Zuohuizi,  He Lu,  Liu Juejun,  Zheng Hongmei DOI: 10.3760/cma.j.cn115989-20190426-00201 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 609-613. Abstract                              [View PDF] [Read Full Text] Objective To analyze the peripheral retinal fluorescence characteristics of normal fundus on […]

Optical coherence tomography angiography of macula in retinopathy of prematurity children with single treatment history

Authors: Zhao Xinyu,  Wu Zhenquan,  Zhang Guoming DOI: 10.3760/cma.j.cn115989-20201104-00740 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 614-618. Abstract                              [View PDF] [Read Full Text] Objective To observe the changes of macular morphology and best corrected visual acuity (BCVA) in children with retinopathy of prematurity […]

Risk factors and treatment outcome of recurrent acanthamoeba keratitis after corneal transplantation

Authors: Feng Lijuan,  Jia Yanni,  Li Fengjie,  Dong Chunxiao,  Shi Weiyun,  Wang Ting DOI: 10.3760/cma.j.cn115989-20200930-00673 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 619-625. Abstract                              [View PDF] [Read Full Text] Objective To investigate the risk factors and treatment outcome of recurrent Acanthamoeba keratitis (AK) […]

Clinical manifestation and treatment of ocular immune reconstitution inflammatory response syndrome in acquired immunodeficiency syndrome patients with cytomegalovirus retinitis

Authors: Kong Wenjun,  Wei Wenbin,  Xie Lianyong,  Chen Chao,  Du Kuifang DOI: 10.3760/cma.j.cn115989-20200317-00179 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 626-631. Abstract                              [View PDF] [Read Full Text] Objective To investigate the ocular characteristics and treatment prognosis of ocular immune reconstruction inflammatory syndrome (IRIS) […]

Analysis of target cytokines affecting OCTA changes following anti-VEGF treatment in PCV eyes

Authors: Xu Qing,  Qiao Lei,  Gong Chaoju,  Feng Ruifang,  Liu Yalu,  Sun Yongcheng,  Zhang Yipeng,  Li Suyan DOI: 10.3760/cma.j.cn115989-20210319-00187 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 632-639. Abstract                               [View PDF] [Read Full Text] Objective To explore the predictability cytokines in aqueous humor affecting […]

Comparison of modulation transfer function between the eyes after small-incision lenticule extraction and femtosecond laser-assisted laser in situ keratomileusis

Authors: Cui Tong,  Wang Yan,  Zhang Lin,  Cheng Wenbo,  Zhao Wei DOI: 10.3760/cma.j.cn115989-20210310-00159 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 515-521. Abstract                              [View PDF] [Read Full Text] Objective To investigate and compare the changes of modulation transfer function (MTF) after small-incision lenticule extraction […]

Changes of corneal anterior surface morphology and higher-order aberrations after Smart

Authors: Wang Shuhan,  Wang Guiqin,  Yu Aomiao,  Zhao Shaozhen,  Wei Ruihua,  Huang Yue DOI: 10.3760/cma.j.cn115989-20191119-00501 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 522-527. Abstract                              [View PDF] [Read Full Text] Objective To compare the changes of corneal asphericity and higher-order aberrations after smart pulse […]

Imaging etiology of pathological myopia results in visual impairment

Authors: Chen Yanru,  Li Xiaoxin,  Li Minghan DOI: 10.3760/cma.j.cn115989-20190321-00127 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 528-533. Abstract                              [View PDF] [Read Full Text] Objective To analyze the imaging etiology of patients having vision loss with pathological myopia. Methods A cross-sectional study was conducted.The […]