Category: 2021, No. 10

Focus of glaucoma prevention and control in China at present

Authors: Chen Xueli,  Chen Junyi,  Chen Yuhong,  Sun Xinghuai DOI: 10.3760/cma.j.cn115989-20210420-00267 Published 2021-10-10 Cite asChin J Exp Ophthalmol, 2021, 39(10): 841-844. Abstract The pathogenesis, diagnosis and management of glaucoma are complex and the population with glaucoma is huge in China now.With the development and popularization of cataract surgery, the visual disability and blindness caused by […]

Quantitative proteomic analysis of human umbilical cord mesenchymal stem cells with pigment epithelium-derived factor gene modification mediated by lentivirus

Authors: Jiang Yilin,  Zhang Xiaomin,  Shao Xianfeng,  An Jinying,  Su Lin,  Jiang Yuanfeng,  Li Xiaorong DOI: 10.3760/cma.j.cn115989-20200609-00408 Published 2021-10-10 Cite asChin J Exp Ophthalmol, 2021, 39(10): 845-851. Abstract Objective To investigate the protein expression changes of human umbilical cord mesenchymal stem cells (hUCMSCs) modified with pigment epithelium-derived factor (PEDF) gene mediated by lentivirus. Methods The […]

Breakdown of blood-retinal outer barrier in mice following acute high intraocular pressure

Authors: Li Wen,  Cao Xing,  Ye Changhua DOI: 10.3760/cma.j.cn115989-20200305-00146 Published 2021-10-10 Cite asChin J Exp Ophthalmol, 2021, 39(10): 852-856. Abstract Objective To investigate the breakdown of blood-retinal outer barrier in the ischemia-reperfusion injury mice following acute intraocular hypertension. Methods Fifty-seven SPF male C57BL/6J mice were selected and divided into the control group and high-intraocular pressure […]

Effect of long-term topical administration of prostaglandins on bulbar conjunctival thickness in rabbits

Authors: Ma Kai,  Yin Chengjuan,  Zhang Zhenyong DOI: 10.3760/cma.j.cn115989-20200707-00481 Published 2021-10-10 Cite asChin J Exp Ophthalmol, 2021, 39(10): 857-862. Abstract Objective To investigate the effect of long-term application of prostaglandin analog drops on bulbar conjunctival thickness in rabbits. Methods Twenty-four healthy New Zealand white rabbits were randomly divided into latanoprost group, carteolol group and blank […]

Studies on the mechanism of inhibitory effect of lithium chloride on the proliferation of human Tenon capsule fibroblasts

Authors: Zou Huihui,  Liu Shanshan,  Liang Ling,  Fan Xiaojun,  Wang Jibing DOI: 10.3760/cma.j.cn115989-20200324-00196 Published 2021-10-10 Cite asChin J Exp Ophthalmol, 2021, 39(10): 863-868. Abstract Objective To investigate the effect of lithium chloride (LiCl) on the gap junctional intercellular communication (GJIC) in human Tenon capsule fibroblasts (HTFs) and its underlying mechanism. Methods The Tenon capsule tissue […]

Outcome evaluation of non-penetrating trabecular surgery combined with suture trabeculotomy for the treatment of primary congenital glaucoma

Authors: Liang Ya,  Chen Zhijun,  Zhou Qing,  Ji Fangfang,  Sun Hong,  Yuan Zhilan DOI: 10.3760/cma.j.cn115989-20201230-00871 Published 2021-10-10 Cite asChin J Exp Ophthalmol, 2021, 39(10): 869-873. Abstract Objective To investigate the efficacy and safety of non-penetrating trabecular surgery combined with nearly 360-degree suture trabeculotomy for the treatment of primary congenital glaucoma (PCG). Methods An observational case […]

Clinical efficacy of ultrasound cycloplasty in the treatment of uncontrolled intraocular pressure after glaucoma surgery

Authors: Cui Qingqing,  Qi Ying,  Huang Xuetao,  Zan Xiaoning,  Yao Renjie,  Zhang Wenjing,  Liu Chaofan DOI: 10.3760/cma.j.cn115989-20200324-00198 Published 2021-10-10 Cite asChin J Exp Ophthalmol, 2021, 39(10): 874-879. Abstract Objective To observe the clinical efficacy of ultrasound cycloplasty (UCP) in the treatment of uncontrolled intraocular pressure (IOP) after glaucoma surgery. Methods An observational case series study […]

Changes and clinical significance of serum interleukin-9 and other T helper cell-related cytokines in patients with acute anterior uveitis

Authors: Bai Huiling,  Fan Aifang,  Liu Qin,  Zhang Shu,  Wang Pengxuan DOI: 10.3760/cma.j.cn115989-20200120-00037 Published 2021-10-10 Cite asChin J Exp Ophthalmol, 2021, 39(10): 880-884. Abstract Objective To explore the role of interleukin (IL)-9 and other T helper (Th) cell-related cytokines in the pathogenesis of acute anterior uveitis. Methods A cross-sectional study was conducted.Thirty-six patients (36 eyes) […]

A comparison study on goniosynechialysis+ phacoemulsification versus simple phacoemulsification for CPACG with PAS≤180° combined cataract

Authors: Chen Yao,  Cheng Gangwei DOI: 10.3760/cma.j.cn115989-20201222-00857 Published 2021-10-10 Cite asChin J Exp Ophthalmol, 2021, 39(10): 885-891. Abstract Objective To compare the efficacy of phacoemulsification+ goniosynechialysis (Phaco-GSL) and Phaco alone for chronic primary angle-closure glaucoma (CPACG) patients with peripheral anterior synechia (PAS)≤180° combined cataract. Methods A cohort study was performed.Fifty-two eyes with CPACG in 40 […]

Association between the function of Schlemm canal and outcome following selective laser trabeculoplasty for primary open-angle glaucoma

Authors: Ran Guangyao,  Sun Anqi,  Li Mu,  Xie Wei,  Zhang Hong DOI: 10.3760/cma.j.cn115989-20190716-00314 Published 2021-10-10 Cite asChin J Exp Ophthalmol, 2021, 39(10): 892-897. Abstract Objective To investigate the relationship between the function of Schlemm canal and the efficacy of selective laser trabeculoplasty (SLT) in patients with primary open-angle glaucoma (POAG). Methods An observational case series […]