Category: Clinical Science

Compound heterozygous mutations of CRB1 gene in a Chinese family with Leber congenital amaurosis by whole exome sequencing

Authors: Cao Yingjie,  Xiao Xiaoqiang,  Chen Shaowan,  Zheng Yuqian,  Chen Haoyu DOI: 10.3760/cma.j.issn.2095-0160.2018.07.008 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 526-530. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the disease-causing mutation in a family with Leber congenital amaurosis (LCA). Methods A Chinese […]

Study of natural history of Chinese patients with choroideremia

Authors:  Han Xiaoxu,  Li Hui,  Wu Shijing,  Sun Zixi,  Zhou Qi,  Sui Ruifang DOI: 10.3760/cma.j.issn.2095-0160.2018.07.007 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 519-525. Abstract                              [Download PDF] [Read Full Text] Objective To provide detailed clinical and molecular genetic findings and describe the characteristics of natural history in Chinese choroideremia (CHM) […]

Mutation analysis of the autosomal dominant Weill-Marchesani syndrome and genotype-phenotype review

Authors: Li Jie,  Xing Yasi,  Li Zhanrong,  Qin Fangyuan,  Dai Shuzhen DOI: 10.3760/cma.j.issn.2095-0160.2018.07.006 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 514-518. Abstract                              [Download PDF] [Read Full Text] Objective To screen the disease-causing genes in an autosomal dominant(AD)Weill-Marchesani syndrome (WMS) family from Henan province in […]

The application of ultra-wide field fluorescein angiography in the evaluation of peripheral vascular changes following retinal vein occlusion

Authors:  Wang Linni,  Yu Rongguo,  Yang Jin,  Hu Liying,  Gong Xue,  Chen Lu,  Li Zhiqing,  Li Xiaorong DOI: 10.3760/cma.j.issn.2095-0160.2018.08.011 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 625-628. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the peripheral vascular findings in eyes with branch retinal vein occlusion (BRVO) and hemi-retinal vein […]

The efficacy of intravitreal injection of conbercept on different types of macular edema induced by branch retinal vein occlusion

Authors:  Xu Na,  Gao Rongyu,  Xu Xinyan,  Zhang Jie,  Sun Xianyong DOI: 10.3760/cma.j.issn.2095-0160.2018.08.010 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 619-624. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the clinical efficacy of intravitreal injection of conbercept on different types of macular edema (ME) induced by branch […]

Intravitreal ranibizumab injection combined trabeculectomy versus Ahmed glaucoma valve implantation in the treatment of neovascular glaucoma

Authors:  Gao Lin,  Liu Wei DOI: 10.3760/cma.j.issn.2095-0160.2018.08.009 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 613-618. Abstract                              [Download PDF] [Read Full Text] Objective To evaluate and compare the efficacy and safety of intravitreal ranibizumab injection combined trabeculectomy and intravitreal ranibizumab injection combined […]

Changes of chemokine receptors expression in the conjunctival epithelial cells and Th-17 cell number in tears of diabetic dry eye disease

Authors: Ren Ning,  Cui Hong,  Sun Lixia,  Li Yingjun DOI: 10.3760/cma.j.issn.2095-0160.2018.09.011 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 710-713. Abstract                               [Download PDF] [Read Full Text] Objective To explore the expression of chemokine receptor 6 (CCR6) and T helper cell 17 (Th-17) in the epithelial cells and tears […]

Conjunctival flora and their antibiotic susceptibility in patients undergoing penetrating intraocular surgeries

Authors: Ren Chunyang,  He Jingna,  Wang Lin,  Liu Shanshan,  Sun Jing,  Cao Yong,  Wang Hailin,  Li Ruoxi,  Zhang Shaodan DOI: 10.3760/cma.j.issn.2095-0160.2018.09.010 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 704-709. Abstract                              [Download PDF] [Read Full Text] Objective To determine the spectrum of conjunctival flora and the antibiotic susceptibility profiles of patients scheduled for […]

Long-term efficacy of intravitreal ranibizumab therapy for idiopathic choroidal neovascularization

Authors: Zhang Ming,  Di Rong,  Kang Qianyan,  Fan Xiaojuan DOI: 10.3760/cma.j.issn.2095-0160.2018.09.009 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 699-703. Abstract                              [Download PDF] [Read Full Text] Objective To observe the long-term clinical efficacy of intravitreal ranibizumab (IVR) in patients with idiopathic choroidal neovascularization (ICNV), and to explore the […]

The prognosis of ocular inflammation index after pterygium surgery based on Oculus Keratograph® 5M and Visual analogue scale

Authors:  Huang Haixiang,  Yuan Jin,  Li Saiqun,  Zhang Henan,  Yang Ruhui,  Deng Yuqing,  Wang Bowen,  Peng Lulu,  Zhong Jing DOI: 10.3760/cma.j.issn.2095-0160.2018.09.008 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 693-698. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the characteristics of ocular surface inflammation index after pterygium excision […]