Category: Experimental Science

Association of light exposure with oxidative damage and apoptosis of human lens epithelial cells

Authors: Wei Shujin,  Nan Li,  Tang Xin,  Ding Na,  Huang Wei,  Sun Erlin DOI: 10.3760/cma.j.issn.2095-0160.2015.04.003 Published 2015-04-10 Cite as Chin J Exp Ophthalmol, 2015,33(4): 300-305. Abstract                              [Download PDF] [Read Full Text] Background Studies showed that light exposure induce the damage of lens […]

Suppression and mechanism of zinc chloride on viability of human lens epithelial cells in vitro

Authors: Du Yuxiang,  Guo Dadong,  Tang Kai,  Si Junkang,  Sha Fang,  Wu Qiuxin,  Bi Hongsheng DOI: 10.3760/cma.j.issn.2095-0160.2015.04.004 Published 2015-04-10 Cite as Chin J Exp Ophthalmol, 2015,33(4): 306-310. Abstract                              [Download PDF] [Read Full Text] Background Zinc ions can inhibit the proliferation of tumor […]

Inhibition of Rho-kinase inhibitor fasudil on the growth and migration of human LECs and extracellular matrix synthesis

Authors: Ren Shijie,  Zhang Fengyan,  Qi Ying,  Cui Kunming DOI: 10.3760/cma.j.issn.2095-0160.2015.04.005 Published 2015-04-10 Cite as Chin J Exp Ophthalmol, 2015,33(4): 311-315. Abstract                              [Download PDF] [Read Full Text] Background Biological behavior changes of human lens epithelial cells (LECs) and extracellular matrix (ECM) synthesis […]

Alleviating effects of α-melanocyte-stimulating hormone on retinal vessel leakage in diabetic rats

Authors: Han Qian,  Zhang Yan,  Bo Qiyu,  Ru Yusha,  Yang Wei,  Li Xiaorong DOI: 10.3760/cma.j.issn.2095-0160.2015.04.006 Published 2015-04-10 Cite as Chin J Exp Ophthalmol, 2015,33(4): 316-322. Abstract                              [Download PDF] [Read Full Text] Background The primary pathogenic basis of diabetic retinopathy (DR) is microangiopathy […]

Role of MsrB1 gene in protection human lens epithelial cells against H2O2-induced apoptosis

Authors: Jia Yi,  Chen Jin DOI: 10.3760/cma.j.issn.2095-0160.2015.04.007 Published 2015-04-10 Cite as Chin J Exp Ophthalmol, 2015,33(4): 323-327. Abstract                              [Download PDF] [Read Full Text] Background Oxidative stress is one of the major risk factors for age-related cataract, methionine sulfoxide reductase B1(MsrB1) has been […]

Suppression of lentiviral vector-mediated mTOR gene silencing on growth of human lens epithelial cell in vitro

Authors: Wang Yihan,  Liu lin DOI: 10.3760/cma.j.issn.2095-0160.2015.04.008 Published 2015-04-10 Cite as Chin J Exp Ophthalmol, 2015,33(4): 328-332. Abstract                              [Download PDF] [Read Full Text] Background Mammalian target of raparrmycin (mTOR) acts as a critical molecular link between growth signals and the processes underlying […]

Change of the focused depth of biconvex Toric intraocular lens in Hwey-Lan Liou schematic eye

Authors: Yang Xin,  Zhang Bin,  Liu Danyan,  Du Yinghua,  Guo Congrong,  Cui Yuexian DOI: 10.3760/cma.j.issn.2095-0160.2015.04.012 Published 2015-04-10 Cite as Chin J Exp Ophthalmol, 2015,33(4): 347-350. Abstract                              [Download PDF] [Read Full Text] Background Toric intraocular lens (IOL) has two optical powers in two […]

Mechanism of embryonic stem cells microenvironment enhancing stemness and inhibiting apoptosis of human limbal stem cells

Authors: Liu Zhiping,  Sha Xiangyin,  Wang Zhichong,  Li Chaoyang,  Liu Ying,  Zhou Jin DOI: 10.3760/cma.j.issn.2095-0160.2015.05.002 Published 2015-05-10 Cite as Chin J Exp Ophthalmol, 2015,33(5): 389-399. Abstract                              [Download PDF] [Read Full Text] Background The fate of adult stem cells is associated with its […]

In vivo and three-dimensional measurement of corneal cell density and size in BALB/c mice

Authors: Zhang Hongmin,  Liu Susu,  Xie Yanting,  Chen Guoming,  He Siyu,  Jin Xin,  Dou Xinyan,  Wang Liya DOI: 10.3760/cma.j.issn.2095-0160.2015.05.004 Published 2015-05-10 Cite as Chin J Exp Ophthalmol, 2015,33(5): 400-405. Abstract                              [Download PDF] [Read Full Text] Background Corneal cell size and density are […]

Establishment of a three-dimensional corneal stroma extracellular matrix fibrosis model induced by transforming growth factor-β1 in vitro

Authors: Jin He,  Luo Shinan,  Fan Zixi,  Li Jie,  Zhou Weiwei,  Li Xia DOI: 10.3760/cma.j.issn.2095-0160.2015.05.005 Published 2015-05-10 Cite as Chin J Exp Ophthalmol, 2015,33(5): 406-411. Abstract                              [Download PDF] [Read Full Text] Background Extracellular matrix (ECM) fibrosis leads to corneal scaring during the […]