Category: Experimental Science

Protection of sulforaphane against hydrogen peroxide-induced bovine trabecular meshwork cell apoptosis

Authors: Liu Yuzhen,  Wang Qiang DOI: 10.3760/cma.j.issn.2095-0160.2016.06.009 Published 2016-06-10 Cite as Chin J Exp Ophthalmol, 2016,34(6): 516-521. Abstract                              [Download PDF] [Read Full Text] Background Evidences indicated that oxidative stress damage is an essential pathological process in primary open angle glaucoma.Sulforaphane (SFN) can […]

Toxic effects of manganese ion eyedrops to ocular anterior segment

Authors: Lei Miao,  Zhu Yu,  Liang Shenzhi DOI: 10.3760/cma.j.issn.2095-0160.2016.06.008 Published 2016-06-10 Cite as Chin J Exp Ophthalmol, 2016,34(6): 510-515. Abstract                              [Download PDF] [Read Full Text] Background A preliminary study determined an application of manganese ion eyedrops in tracing observation of visual system […]

Protective effect of NLRP12 knockdown on retinal damage in rats with ocular hypertension and its mechanism of inhibiting cell pyroptosis

Authors: Song Weiqiong,  He Fang,  Du Lingfang,  Tan Huaxia,  Liu Dan DOI: 10.3760/cma.j.cn115989-20211021-00572 Published 2023-02-10 Cite as Chin J Exp Ophthalmol, 2023, 41(2): 110-118. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the effect and mechanism of NOD-like receptor family pyrin […]

Promoting effect of AGTR1 blocker olmesartan on the apoptosis of HTF and its mechanism

Authors: Wang Lijun,  Li Hongsong,  Zhang Wenyi,  Shao Meilin,  Ren Meimei,  Wang Jianming DOI: 10.3760/cma.j.cn115989-20220601-00262 Published 2023-02-10 Cite as Chin J Exp Ophthalmol, 2023, 41(2): 119-126. Abstract                            [Download PDF] [Read Full Text] Objective To study the effect and mechanism of angiotensin type 1 […]

Search for potential target genes in dexamethasone-induced open-angle glaucoma by bioinformatics

·Experimental Research· Potential target genes detected by bioinformatics in dexamethasone-induced open-angle glaucoma Liu Liling, Li Deling, Zeng Weiting, Zhang Xinyi, Xu Jiangang, Yu Minbin State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Certer, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou 510060, China Corresponding author: Yu Minbin, Email: yuminbin@mail.sysu.edu.cn      Abstract    […]

Therapeutic effect of small extracellular vesicles derived from mesenchymal stem cells on retinal light injury and its mechanism

·Experimental Research· The therapeutic effect and mechanism of small extracellular vesicles derived from mesenchymal stem cells (MSCs) on retinal light injury Yu Bo1, Wang Kang2, Zhang Mingliang1, Xing Xiaoli1, Li Xiaorong1, Zhang Xiaomin1 1Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye institute and School […]

Inhibitory effects of N-acetylcysteine and salubrinal on apoptosis of retinal pigment epithelial cells induced by all-trans-retinoic acid

Authors: Wu Juan,  Cui Dongmei,  Zeng Junwen DOI: 10.3760/cma.j.cn115989-20200414-00262 Published 2023-01-10 Cite as Chin J Exp Ophthalmol, 2023, 41(1): 16-21. Abstract                                    [Download PDF] [Read Full Text] Objective To observe the effect of the antioxidant N-acetylcysteine (NAC) and selective endoplasmic […]

Inhibitory effect of ranibizumab on retinal oxidative stress in a rat model of choroidal neovascularization and its mechanism

Authors: Yang Yanzhen,  Zhuang Xianli,  Li Shujie,  Zhang Ying,  Yang Jiagan,  Li Lulu DOI: 10.3760/cma.j.cn115989-20210930-00543 Published 2023-01-10 Cite as Chin J Exp Ophthalmol, 2023, 41(1): 22-28. Abstract                                    [Download PDF] [Read Full Text] Objective To study the effect of ranibizumab […]

Feasibility of corneal epithelial transplantation with polyethylene glycol hydrogel membrane as a carrier for limbal stem cell deficiency

·Experimental Research· Feasibility of corneal epithelial transplantation with polyethylene glycol hydrogel membrane as a carrier for limbal stem cell deficiency Guo Yiyuan1, Xian Huimin2, Shereen Tan3, Qiang Fu3,4, Jin Xin1, Mark Daniel5, Greg.G.Qiao2, Zhang Hong1 1Department of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China; 2Department of Cardiology, The 2nd Affiliated […]

Pressure-induced differentiation of rabbit retinal stem cells into retinal ganglion cells

Authors: Dai Min,  Kang Zefeng,  Hu Zhulin,  Li Yan DOI: 10.3760/cma.j.cn115989-20200519-00361 Published 2022-12-10 Cite as Chin J Exp Ophthalmol, 2022, 40(12): 1134-1140. Abstract                              [View PDF] [Read Full Text] Objective To investigate the effect of pressure on the differentiation of rabbit retinal stem […]