Category: Experimental Science

Inhibition of naringenin complex with β-cyclodextrin on experimental choroidal neovascularization in rats

Authors: Xu Xinrong,  Yu Haitao,  Hang Li,  Shao Yan,  Ding Shuhua,  Yang Xuewen DOI: 10.3760/cma.j.issn.2095-0160.2015.12.007 Published 2015-12-10 Cite as Chin J Exp Ophthalmol, 2015,33(12): 1083-1088. Abstract                              [Download PDF] [Read Full Text] Background Choroidal neovascularization (CNV) leads to blindness in many fundus diseases.Study […]

Inhibitory effect of radixin shRNA on retinal neovascularization induced by hyperoxia in mice

Authors: Wang Longmei,  Yang Xia,  Yan Lin,  Liu Ting,  Dong Xiaoguang,  Xu Haifeng DOI: 10.3760/cma.j.issn.2095-0160.2015.12.008 Published 2015-12-10 Cite as Chin J Exp Ophthalmol, 2015,33(12): 1089-1094. Abstract                              [Download PDF] [Read Full Text] Background Retinal neovascularization is pathological basis of a variety of fundus […]

Effects of macrophages and monocyte chemoattractant protein-1 during experimental choroidal neovascularization

Authors: Zhang Shukun,  Xie Ping,  Yuan Dongqing,  Liu Qinghuai DOI: 10.3760/cma.j.issn.2095-0160.2015.12.009 Published 2015-12-10 Cite as Chin J Exp Ophthalmol, 2015,33(12): 1095-1101. Abstract                              [Download PDF] [Read Full Text] Background Choroidal neovascularization (CNV) is one of the primary causes leading to visual damage in […]

Dynamic expression of intercellular adhesion molecule-1 in laser-induced choroidal neovascularization in Brown Norway rats

Authors: Gao Xiaoyan,  He Shouzhi DOI: 10.3760/cma.j.issn.2095-0160.2015.12.011 Published 2015-12-10 Cite as Chin J Exp Ophthalmol, 2015,33(12): 1103-1107. Abstract                              [Download PDF] [Read Full Text] Background Extracellular matrix (ECM) has various kinds of types and important biological function.The important role of ECM during choroidal […]

Modification and evaluation of ameliorative oxygen-induced retinopathy mouse model

Authors: Liu Aihua,  Sun Jing,  Zhang Hong DOI: 10.3760/cma.j.issn.2095-0160.2015.12.012 Published 2015-12-10 Cite as Chin J Exp Ophthalmol, 2015,33(12): 1108-1112. Abstract                            [Download PDF] [Read Full Text] Background Retinal neovascularization is associated with various disorders.Studying the pathogenesis of retinal neovascularization is of important significance.Oxygen-induced retinopathy(OIR) […]

Protection of sulforaphane against hydrogen peroxide-induced bovine trabecular meshwork cell apoptosis

Authors: Liu Yuzhen,  Wang Qiang DOI: 10.3760/cma.j.issn.2095-0160.2016.06.009 Published 2016-06-10 Cite as Chin J Exp Ophthalmol, 2016,34(6): 516-521. Abstract                              [Download PDF] [Read Full Text] Background Evidences indicated that oxidative stress damage is an essential pathological process in primary open angle glaucoma.Sulforaphane (SFN) can […]

Toxic effects of manganese ion eyedrops to ocular anterior segment

Authors: Lei Miao,  Zhu Yu,  Liang Shenzhi DOI: 10.3760/cma.j.issn.2095-0160.2016.06.008 Published 2016-06-10 Cite as Chin J Exp Ophthalmol, 2016,34(6): 510-515. Abstract                              [Download PDF] [Read Full Text] Background A preliminary study determined an application of manganese ion eyedrops in tracing observation of visual system […]

Protective effect of NLRP12 knockdown on retinal damage in rats with ocular hypertension and its mechanism of inhibiting cell pyroptosis

Authors: Song Weiqiong,  He Fang,  Du Lingfang,  Tan Huaxia,  Liu Dan DOI: 10.3760/cma.j.cn115989-20211021-00572 Published 2023-02-10 Cite as Chin J Exp Ophthalmol, 2023, 41(2): 110-118. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the effect and mechanism of NOD-like receptor family pyrin […]

Promoting effect of AGTR1 blocker olmesartan on the apoptosis of HTF and its mechanism

Authors: Wang Lijun,  Li Hongsong,  Zhang Wenyi,  Shao Meilin,  Ren Meimei,  Wang Jianming DOI: 10.3760/cma.j.cn115989-20220601-00262 Published 2023-02-10 Cite as Chin J Exp Ophthalmol, 2023, 41(2): 119-126. Abstract                            [Download PDF] [Read Full Text] Objective To study the effect and mechanism of angiotensin type 1 […]

Search for potential target genes in dexamethasone-induced open-angle glaucoma by bioinformatics

·Experimental Research· Potential target genes detected by bioinformatics in dexamethasone-induced open-angle glaucoma Liu Liling, Li Deling, Zeng Weiting, Zhang Xinyi, Xu Jiangang, Yu Minbin State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Certer, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou 510060, China Corresponding author: Yu Minbin, Email: yuminbin@mail.sysu.edu.cn      Abstract    […]