Category: Experimental Science

The efficiency and safety assessment of Entranster™ nanoparticle carrier for CD25 siRNA transfection in rat cornea

Authors:Qin Qin,  Shi Yunjie,  Zhao Min DOI: 10.3760/cma.j.issn.2095-0160.2016.10.005 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 888-895. Abstract                              [Download PDF] [Read Full Text] Background Gene transfection is an effective therapeutic avenue to target many kinds of eye diseases.Non-viral vectors with high transfection efficiency, long-term expression, […]

Identification of pathgenic bacteria in aqueous and vitreous of endophthalmitis by 16S rDNA sequencing technique

Authors: Yang Baoxia,  Li Hong,  Kong Fanfang,  Huang Yusen DOI: 10.3760/cma.j.issn.2095-0160.2016.10.004 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 883-887. Abstract                              [Download PDF] [Read Full Text] Background Endophthalmitis is a serious complication of intraocular surgery.Conventional identification methods for bacteria are becterial culture and smear method, […]

Detection and analysis of differential gene expression between benign lymphoepithelial lesion of lacrimal gland and orbital cavernous hemangioma

Authors:Li Jing,  Ge Xin,  Ma Jianmin,  Wang Xiaona,  Liu Xiao DOI: 10.3760/cma.j.issn.2095-0160.2016.10.003 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 878-882. Abstract                            [Download PDF] [Read Full Text] Background Benign lymphoepithelial lesion of lacrimal gland is not a common orbital disease in clinic, which mainly presented as […]

Changes of collapsin response mediator protein-2 and its phosphorylated protein levels following optic nerve injury

Authors:Chen Xiaofan,  Yuan Rongdi,  Ye Jian,  Chen Chunlin DOI: 10.3760/cma.j.issn.2095-0160.2016.10.002 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 874-877. Abstract                            [Download PDF] [Read Full Text] Background Collapsin response mediator protein-2 (CRMP-2) can promote the growth of axons, but CRMP-2 occurs hyperphosphorylation under the induction of cyclin-dependent […]

A comparative study on protective effect of optical nerve between crocin and erigeron breviscapus in chronic ocular hypertensive rats

Authors:Lyu Bochang,  Xu Zhiguo,  Chen Tao,  Shi Juan,  Yang Xinguang DOI: 10.3760/cma.j.issn.2095-0160.2016.11.007 Published 2016-11-10 Cite as Chin J Exp Ophthalmol, 2016,34(11): 990-996. Abstract                              [Download PDF] [Read Full Text] Background The primary cause of glaucomatous optic nerve damage is apoptosis of nerve cell and disorder of retinal circulation.Erigeron breviscapus is confirmed to have […]

Screening of optimal ultrasound parameters after intravitreal injection of microbubble in normal rabbit eyes

Authors:Shen Xiaoli,  Li Qiang,  Huang Lina,  Zhao Jun,  Fan Ning DOI: 10.3760/cma.j.issn.2095-0160.2016.11.005 Published 2016-11-10 Cite as Chin J Exp Ophthalmol, 2016,34(11): 983-988. Abstract                              [Download PDF] [Read Full Text] Background Ultrasound microbubbles play important effects on delivery of drug or gene, which can significantly improve the transfection efficiency of drug or gene after […]

Methodology of a rabbit model of chronic dacryocystitis

Authors:Jin Jing,  Xiang Nan,  Liu Rong,  Hu Weikun DOI: 10.3760/cma.j.issn.2095-0160.2016.11.004 Published 2016-11-10 Cite as Chin J Exp Ophthalmol, 2016,34(11): 978-982. Abstract                               [Download PDF] [Read Full Text] Background Chronic dacryocystitis is a common infectious lacrimal apparatus disease.Whether infection factors or lacrimal duct obstruction play a major role in the process of recurrent […]

The Th1/Th2-associated cytokines in the animal model of Graves ophthalmopathy

Authors:Yang Yuli,  Luo Qingli,  Lyu Hongbin DOI: 10.3760/cma.j.issn.2095-0160.2016.11.003 Published 2016-11-10 Cite as Chin J Exp Ophthalmol, 2016,34(11): 971-977. Abstract                              [Download PDF] [Read Full Text] Background Graves opthalmopathy (GO) is an autoimmune disease, and its pathogenesis is not clear.Recent reports found that the imbalance of Th1/Th2 type immune response may be […]

The effects of fluoxetine and its machanism on the restores of visual cortex plasticity in the adult rats by visual electrophysiological research

Authours:Xie Laiqing,  Xu Guoxu,  Ni Yong,  Wei Xiaohong,  Lou Hui DOI: 10.3760/cma.j.issn.2095-0160.2016.11.002 Published 2016-11-10 Cite as Chin J Exp Ophthalmol, 2016,34(11): 965-970. Abstract                              [Download PDF] [Read Full Text] Background Fluoxetine (Flx), a selective serotonin reuptake inhibitor, promotes neurogenesis and synaptogenesis in the adult hippocampus.So it is inferred that Flx plays a role […]

Model making of radioactive optic nerve injury

Authors:Cheng Xianhua,  Gu Xuejun,  Li Zhiying,  Ji Jianping DOI: 10.3760/cma.j.issn.2095-0160.2016.12.009 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1092-1096. Abstract                              [Download PDF] [Read Full Text] Background Radiation-induced optic neuropathy (RION) is a severe complication after radiotherapy for head and neck cancer, which threatens the visual acuity and quality of life […]