Authors: Lai Qinghua, Gao Yingying, Li Wei, Zuo Chengyou, Li Qingmin DOI: 10.3760/cma.j.issn.2095-0160.2019.06.006 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 432-438. Abstract [View PDF] [Read Full Text] Objective To investigate the effects of cryptotanshinone and tanshinone ⅡA, two major monomer components of tanshinone, on the proliferation, differentiation and […]
Category: Experimental Science
Protective effects of intravitreal injection of nerve growth factor on retinal ganglion cells in early diabetic rats
Authors: Lyu Hang, Wang Qichang, Tang Luosheng DOI: 10.3760/cma.j.issn.2095-0160.2019.06.005 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 425-431. Abstract [View PDF] [Read Full Text] Objective To investigate the protective effect of intravitreal injection of nerve growth factor (NGF) on apoptosis of retinal ganglion cells (RGCs) in early […]
Dynamic changes of ocular surface tissue of diabetic dry eye in mice
Authors: Wang Qian, Wan Lei, Li Jing, Zhou Qingjun DOI: 10.3760/cma.j.issn.2095-0160.2019.06.004 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 419-424. Abstract [View PDF] [Read Full Text] Objective To explore the occurring and developing characteristics of dry eye syndrome in type 1 diabetic mouse model induced with streptozotocin (STZ)-intraperitoneal […]
The effect and mechanisms of chloride channel blocker NPPB on TGF-β1 induced HConF fibrosis
Authors: Sun Lixia, Li Yingjun, Cui Renzhe, Lu Di, Zheng Yajuan DOI: 10.3760/cma.j.issn.2095-0160.2019.06.003 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 411-418. Abstract [View PDF] [Read Full Text] Objective To study the effect and mechanisms of chloride channel blocker 5-Nitro-2-(3-phenylpropylamino) benzoic acid (NPPB) on thansforming growth factor β1 (TGF-β1) […]
The inhibitory effect of FoxF2 shRNA on the expression of extracellular matrix of human trabecular meshwork
Authors: Liu Aihua, Gao Meizi, Huang Liangyu, Liu Xun, Su Ruihong, Zhao Jinzhi, Wang Liming, Zhang Xiaomin, Li Xiaorong, Dong Lijie DOI: 10.3760/cma.j.issn.2095-0160.2019.06.002 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 405-410. Abstract [View PDF] [Read Full Text] Objective To explore the role of forkhead box F2 (FoxF2) in the extracellular matrix of trabecular […]
The efficiency and safety assessment of Entranster™ nanoparticle carrier for CD25 siRNA transfection in rat cornea
Authors：Qin Qin, Shi Yunjie, Zhao Min DOI: 10.3760/cma.j.issn.2095-0160.2016.10.005 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 888-895. Abstract [Download PDF] [Read Full Text] Background Gene transfection is an effective therapeutic avenue to target many kinds of eye diseases.Non-viral vectors with high transfection efficiency, long-term expression, […]
Identification of pathgenic bacteria in aqueous and vitreous of endophthalmitis by 16S rDNA sequencing technique
Authors: Yang Baoxia, Li Hong, Kong Fanfang, Huang Yusen DOI: 10.3760/cma.j.issn.2095-0160.2016.10.004 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 883-887. Abstract [Download PDF] [Read Full Text] Background Endophthalmitis is a serious complication of intraocular surgery.Conventional identification methods for bacteria are becterial culture and smear method, […]
Detection and analysis of differential gene expression between benign lymphoepithelial lesion of lacrimal gland and orbital cavernous hemangioma
Authors：Li Jing, Ge Xin, Ma Jianmin, Wang Xiaona, Liu Xiao DOI: 10.3760/cma.j.issn.2095-0160.2016.10.003 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 878-882. Abstract [Download PDF] [Read Full Text] Background Benign lymphoepithelial lesion of lacrimal gland is not a common orbital disease in clinic, which mainly presented as […]
Changes of collapsin response mediator protein-2 and its phosphorylated protein levels following optic nerve injury
Authors：Chen Xiaofan, Yuan Rongdi, Ye Jian, Chen Chunlin DOI: 10.3760/cma.j.issn.2095-0160.2016.10.002 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 874-877. Abstract [Download PDF] [Read Full Text] Background Collapsin response mediator protein-2 (CRMP-2) can promote the growth of axons, but CRMP-2 occurs hyperphosphorylation under the induction of cyclin-dependent […]
A comparative study on protective effect of optical nerve between crocin and erigeron breviscapus in chronic ocular hypertensive rats
Authors：Lyu Bochang, Xu Zhiguo, Chen Tao, Shi Juan, Yang Xinguang DOI: 10.3760/cma.j.issn.2095-0160.2016.11.007 Published 2016-11-10 Cite as Chin J Exp Ophthalmol, 2016,34(11): 990-996. Abstract [Download PDF] [Read Full Text] Background The primary cause of glaucomatous optic nerve damage is apoptosis of nerve cell and disorder of retinal circulation.Erigeron breviscapus is confirmed to have […]