Clinical choice of treatment regimens for recurrent corneal erosion

Authors: Lin Lanruo,  Zhu Siquan
DOI: 10.3760/cma.j.cn115989-20200331-00228
Published 2022-02-10
Cite asChin J Exp Ophthalmol, 2022, 40(2): 187-192.

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Recurrent corneal erosion (RCE), a common disease caused by repeated episodes of corneal epithelial defects, is characterized by the sudden onset of eye pain, usually upon first awakening.Among many causes of the disease, trauma is the most common one, followed by epithelial basement membrane dystrophy.The disease can be diagnosed via the characteristic medical history, ocular symptoms and slit-lamp examination.Treatment of RCE includes both conservative management and surgical management.Conservative treatment is the first choice for the primary patients, including medication, bandage contact lens, application of serum drops, coverage of cryopreserved amniotic membrane, etc.The appropriate surgical procedures should be performed in patients when the conservative therapy failed.Surgical treatment mainly includes epithelial debridement, diamond burr polishing, anterior stromal puncture, alcohol delamination, phototherapeutic keratectomy, photorefractive keratectomy, femtosecond laser-assisted lamellar keratectomy, etc.RCE treatment progress was comprehensively reviewed in this article to provide references for clinical therapy.

Key words:

Corneal diseases; Epithelium, corneal; Therapeutics; Recurrent corneal erosion; Contact lenses, bandage; Phototherapeutic keratectomy

Contributor Information

Lin Lanruo

Sixth Clinical Medical College, Capital Medical University, Beijing 100029, China

Lin Lanruo is working at the Department of Ophthalmology, First Clinical Medical College, Peking University Health Science Center, Beijing 100034, China

Zhu Siquan

Department of Ophthalmology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

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