Comparison of clinical effects between TransPRK with intelligent pulse technology and SMILE for myopia

Authors: Du Yuqin,  Zhou Chunyang,  Zhou Yuehua,  Li Yu,  Su Dan,  Wen Long

DOI: 10.3760/cma.j.cn115989-20200327-00216
Published 2020-06-10
Cite as Chin J Exp Ophthalmol, 2020,38(06): 489-493.

Abstract

Objective

To compare the clinical outcome of transepithelial photorefractive keratectomy (TransPRK) using 1 050 Hz ablation frequency and intelligent pulse technique (SPT) and small incision lenticule extraction (SMILE) for myopia and astigmatism.

Methods

A cohort study was performed.Eighty-five eyes of 43 patients who received TransPRK for myopia and 85 eyes of 46 patients who received SMILE for myopia in the Ineye Hospital of Chengdu University of TCM were enrolled from August 2017 to April 2018.The follow-up duration was 6 months.The changes of visual acuity and diopter were observed and compared before and after operation, and the predictability, stability, safety, effectiveness and long-term vision were compared between the different surgeries.This study complied with the Declaration of Helsinki and the study protocol was approved by the Ethics Committee of Ineye Hospital of Chengdu University of TCM.

Results

The refractive power tended to be emmetropic and relatively stable in the TransPRK group, and the refraction varied from mild hyperopia to emmetropic gradually during 6 months after SMILE.There was no significant difference in the spherical equivalent (SE) between the two groups before and after operation (all at P>0.05). No significant difference was found in mean validity index between the two groups at 6 months after surgery (1.189±0.248 vs.1.120±0.205; t=1.862, P=0.065). The uncorrected visual acuity (UCVA) in the SMILE group was significantly higher than that in the TransPRK group at 7 days and 1 month after surgery (P<0.05), and there was no significant difference in UCVA between the two groups at 3 months and 6 months after surgery (P>0.05). The safety index at 6 months after surgery in the TransPRK group was 1.209±0.222, which was significantly higher than 1.143±0.178 in the SMILE group, with a significant difference between the two groups (t=2.024, P=0.045).

Conclusions

The predictability, stability, safety, effectiveness and long-term vision are good after TransPRK with SPT and SMILE for myopia and astigmatism.The safety index is better in TransPRK compared with SMILE, and the restoration of vision is faster after SMILE than that after TransPRK.

Key words:

Myopia/surgery; Laser/therapy use; Outcome; Transepithelial photorefractive keratectomy; Small incision lenticule extraction; Intelligent pulse technique

Contributor Information

Du Yuqin
Eye School of Chengdu University of TCM, Ineye Hospital of Chengdu University of TCM, Key Laboratory of Sichuan Province Ophthalmopathy Prevention & Cure and Visual Function Protection with TCM, Chengdu 610036, China
Zhou Chunyang
Eye School of Chengdu University of TCM, Ineye Hospital of Chengdu University of TCM, Key Laboratory of Sichuan Province Ophthalmopathy Prevention & Cure and Visual Function Protection with TCM, Chengdu 610036, China
Zhou Yuehua
Eye School of Chengdu University of TCM, Ineye Hospital of Chengdu University of TCM, Key Laboratory of Sichuan Province Ophthalmopathy Prevention & Cure and Visual Function Protection with TCM, Chengdu 610036, China
Li Yu
Eye School of Chengdu University of TCM, Ineye Hospital of Chengdu University of TCM, Key Laboratory of Sichuan Province Ophthalmopathy Prevention & Cure and Visual Function Protection with TCM, Chengdu 610036, China
Su Dan
Eye School of Chengdu University of TCM, Ineye Hospital of Chengdu University of TCM, Key Laboratory of Sichuan Province Ophthalmopathy Prevention & Cure and Visual Function Protection with TCM, Chengdu 610036, China
Wen Long
Eye School of Chengdu University of TCM, Ineye Hospital of Chengdu University of TCM, Key Laboratory of Sichuan Province Ophthalmopathy Prevention & Cure and Visual Function Protection with TCM, Chengdu 610036, China
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