Focusing on clinical activity score of thyroid eye disease suitable for Chinese population

Authors: Lei Chaoyu, Wang Hui, Sun Jing, Zhou Huifang
DOI: 10.3760/cma.j.cn115989-20240418-00112
 

Citation

Lei Chaoyu, Wang Hui, Sun Jing, et al. Focusing on clinical activity score of thyroid eye disease suitable for Chinese population[J]. Chin J Exp Ophthalmol, 2024, 42(11):977-982. DOI: 10.3760/cma.j.cn115989-20240418-00112.

ABSTRACT                    [Download PDF] [Read Full Text]

Thyroid eye disease (TED) is an orbital disease closely associated with thyroid disorders, with 25%-50% of patients with diffuse toxic goiter (Graves Disease) developing secondary TED, which can lead to blindness and disability and significantly impair patients’ visual function and quality of life.Activity staging is a crucial assessment index for TED and is essential for clinical evaluation, treatment planning, and prognosis.The Clinical Activity Score (CAS) is currently the most widely used method for this purpose both domestically and internationally.To improve the accuracy and consistency of CAS evaluations, the European Group of Graves’ Orbitopathy (EUGOGO) recommended the use of a CAS scoring atlas in the TED guidelines.However, existing atlases are primarily based on Caucasians.Considering the anatomical differences in the orbit between Chinese and Caucasians and the resulting divergent ocular characteristics, there is a need for a comprehensive interpretation of the CAS scoring details in the current guidelines.This should be followed by further refinement to tailor the CAS scoring criteria to Chinese patients with TED.Such measures will standardize the operational methods and judgment criteria of CAS scoring in China, thereby providing a reliable basis for the accurate diagnosis and treatment of the disease.

Thyroid eye disease;Clinical activity score;Atlas

Authors Info & Affiliations 

Lei Chaoyu
Department of Ophthalmology, Shanghai Ninth People’s Hospital, Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Center for Basic Medical Research and Innovation in Visual System Diseases of Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China
Wang Hui
Department of Ophthalmology, Shanghai Ninth People’s Hospital, Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Center for Basic Medical Research and Innovation in Visual System Diseases of Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China
Sun Jing
Department of Ophthalmology, Shanghai Ninth People’s Hospital, Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Center for Basic Medical Research and Innovation in Visual System Diseases of Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China
Zhou Huifang
Department of Ophthalmology, Shanghai Ninth People’s Hospital, Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Center for Basic Medical Research and Innovation in Visual System Diseases of Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China
(Read 18 times, 1 visits today)