Focusing on systematic therapy of dry eye

Dry eye is an ocular surface disease caused by multiple factors, which is characterized by imbalance of tear film homeostasis, changes of ocular surface micro-environments and ocular uncomfortable symptoms.Tear film instability, tear hyperosmolarity, ocular surface inflammation and damage and corneal neurosensory abnormalities play etiological roles in the process of dry eye.Dry eye seriously affects work and life quality of the patients.With the progress of science and technology, the treatment of dry eye is becoming more diversified.The therapeutic methods are different for mild, moderate and serous dry eye.The choice of therapies actually depends on the individual state and condition of therapeutic institutions.A systemic, standardized and comprehensive therapy is associated with the improvement of treatment outcome.This article systematically summarizes the traditional and emerging treatments of dry eye, which are clinically feasible and can provide reference for choosing treatment methods.