Category: Uncategorized

Advances of ocular surface drug delivery system

Authors: Chen Xiang,  Xu Wen DOI: 10.3760/cma.j.cn115989-20200123-00038 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1091-1096. Abstract Due to the anatomical and physical barriers, the low bioavailability of eye drops has become the primary problem in optimizing efficacy.Drug delivery system can reduce administration frequency and keep the therapeutic concentration while increasing ocular surface retention […]

Clinical phenotype and maternal mutation analysis of Leber hereditary optic neuropathy

Authors:Huang Lyuzhen,  Li Tianqi,  Wang Bin,  Li Xiaoxin DOI: 10.3760/cma.j.issn.2095-0160.2016.10.012 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 920-924. Abstract Background Leber hereditary optic neuropathy (LHON) is a maternally inherited disease caused by mitochondrial DNA (mtDNA) mutation with the common mutation sites of m. 3460 G>A, m.11778 G>A and m. 14484 T>C, and other mutation […]

Rapid assessment of children’s active trachoma in rural area of Naxi district and Jiangyang district of Luzhou in China during 10 years

Authors: Qiao Lifeng,  Lei Chuntao,  Fan Yingchuan,  Zhang Xiaoqi,  Zhou Menglan DOI: 10.3760/cma.j.issn.2095-0160.2017.06.013 Published 2017-06-10 Cite as Chin J Exp Ophthalmol, 2017,35(06): 548-551. Abstract Background Trachoma is a serious blinding eye disease.At present, the incidence rate of trachoma in China has been greatly reduced with the unremitting efforts of World Health Orgnization (WHO) and Chinese government.However, in some economically underdeveloped […]

Survey of medical resources of eye care in Tibet autonomous region

Authors: Dan Zengrenqing,  Li Xiaoxin,  Tsedenyangkyi null DOI: 10.3760/cma.j.issn.2095-0160.2017.08.016 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 743-746. Abstract Background The improvement of the eye care system has being a strong guarantee for blindness prevention.However, medical resources of eye care in Tibet autonomous region cannot jet meet the effective requirement.Knowing the present situation of medical resources of […]

Associations of single nucleotide polymorphisms of UCP genes with diabetic retinopathy in Chinese Han population

Authors: Jin Peiyao,  Li Zhiqiang,  Xu Xian,  He Jiangnan,  Chen Jianhua,  Xu Xun,  Du Xuan,  Bai Xuelin,  Zhang Bo,  He Xiangui,  Lu Lina,  Zhu Jianfeng,  Shi Yongyong,  Zou Haidong DOI: 10.3760/cma.j.issn.2095-0160.2017.08.015 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 737-742. Abstract Background Researches showed that elevatory blood glucose level results in long-term damage of cells and tissue, or metabolic memory phenomenon, and manipulation of hyperglycemic memory is a […]

Therapeutic effects of induced pluripotent stem cells on primary open angle glaucoma

Authors: Zhu Wei DOI: 10.3760/cma.j.issn.2095-0160.2017.09.002 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 773-777. Abstract Glaucoma is an group of ocular disease associated with the degeneration of retinal ganglion cells and it finally causes vision loss.Primary open angle glaucoma (POAG) is a main type of glaucoma worldwide.The primary reason of POAG is elevated intraocular pressure […]

Clinical management of bacterial keratitis in the new era

Authors: Mingwu Wang DOI: 10.3760/cma.j.issn.2095-0160.2017.11.002 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 966-969. Abstract Bacterial keratitis is a common infectious keratitis.Patients often end up with severe vision loss even after the infection is completely eradicated.With the increasing resistance of pathogens to antibiotics, treatment of bacterial keratitis has become increasingly difficult.Facing such an emerging challenge, […]

Feasibility and effectiveness of a health examination center-based opportunistic eye diseases screening

Authors: Zhang Shaodan,  Liang Yuanbo,  Sun Jing,  Liu Shanshan,  Xu Lin,  Wang Hailin,  Liu Chi,  Li Ruoxi DOI: 10.3760/cma.j.issn.2095-0160.2017.12.013 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1120-1125. Abstract Background Blindness and low vision represent significant public health issues in China.Late diagnosis is the major reason for the irreversible vision impairment.A feasible, cost-effective screening and referral program is very important for the […]

Is glaucoma suitable for community screening?

Authors: Jiang Junhong,  Ye Cong,  Liang Yuanbo DOI: 10.3760/cma.j.issn.2095-0160.2018.04.014 Published 2018-04-10 Cite as Chin J Exp Ophthalmol, 2018,36(4): 294-298. Abstract Glaucoma is the leading cause of irreversible blindness worldwide.Screening for glaucoma is a critical intervention to identify individuals at an earlier stage of the disease.However, there is controversy about the necessity of glaucoma screening.Screening is a critical intervention […]

Relationship between the changes of high-sensitivity C-reactive protein and retinal vessel diameter in the middle-aged and elderly: the Kailuan Study

Authors: Liu Xinxin,  Lu Aidong,  Wang Yaxing,  Wei Wenbin,  Chen Shuohua,  Wu Shouling DOI: 10.3760/cma.j.issn.2095-0160.2018.08.012 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 629-635. Abstract Objective To investigate the relationship between high-sensitivity C-reactive protein (hsCRP) and retinal vascular diameter. Methods This study was a cross-sectional study, the population was from the Kailuan study (clinical trial research registration NO.: ChiCTR-TNC-1100 1489) […]