Authors: Tan Nan, Zheng Guangying, Chen Gang, Yuan Chaofeng, Zhao Xiaohua, Zhang Cuifang
Abstract [Download PDF] [Read Full Text]
With the development of refractive surgery, phakic intraocular lens implantation (PIOL) for high myopia is proving its outstanding merits in short-term treating outcomes.However, its long-term safety and effectiveness were still in more attention.
This study was to evaluate and compare the long-term safety, stability and efficacy of Verisyse PIOL implantation with implantable contact lens (ICL) implantation for high myopia.
The clinical data of 18 eyes (9 patients) who received Verisyse iris-claw intraocular lens implantation for high myopia and matched 22 eyes (11 patients) who received ICL implantation for high myopia from 2009 to 2011 were retrospectively analyzed.The patients were followed-up for 2 years after surgery.Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), spherical equivalence (SE), axial length, corneal endothelial cell density (ECD), contrast sensitivity (CS), wave-front aberrations and postoperative complications were recorded during the following-up.The efficacy index, predictable and safety index were compared between the two groups.
There was no significant difference in UCVA, BCVA and SE between Verisyse group and ICL group (t=0.92, 1.32, 4.32; all at P>0.05). Non-glare CS under the 1.5, 3.0, 6.0, 12.0 and 18.0 c/d spatial frequencies were insignificantly different between the two groups(Z=0.782, 0.956, 0.495, 0.874, 0.293; all at P>0.05), and the similar outcomes were found in glare CS (Z=0.985, 1.254, 0.896, 1.652, 0.492; all at P>0.05) in postoperative 2 years.Root meas square of total high order aberration (RMSh), vertical-trefoil, vertical-coma, horizontal-coma, spherical aberration(SA), were significantly elevated in the Verisyse group compared with the ICL group (Z=4.72, 4.24, 3.12, 3.65, 2.16; all at P<0.05). The mean efficacy index was 108.49±16.62 in the Verisyse group and 106.71±15.88 in the ICL group, showing a significant difference (t=0.54, P>0.05). The mean safety index was 140.56±33.89 in the Verisyse group and 143.34±34.56 in the ICL group, with a significant difference between them (t=0.29, P>0.05). The mean predictable index was -0.25(-0.97, 4.23)in the Verisyse group and 0.98 (-1.44, 1.52) in the ICL group, and the difference was significant(Z=-2.68, P<0.05).
Both Verisyse PIOL implantation and ICL implantation for high myopia are safe, predictable and effective.The vusial quality and predictability of ICL implantation are much better than Verisyse PIOL implantation.A long-term effect should be observed for the further evaluation.