Optical coherence tomography angiography in the evaluation of glaucomatous damage

Authors: Zhang Yang,  Li Yuanyuan,  Yuan Huiping

DOI: 10.3760/cma.j.cn115989-20191210-00537
Published 2021-04-10
Cite asChin J Exp Ophthalmol, 2021, 39(4): 365-368.

Abstract

Glaucoma is a neurodegenerative disease, which is characterized by a concave atrophy of the optic disc and a characteristic defect of the visual field.The current diagnosis and evaluation of glaucoma are mainly based on fundus photography, optical coherence tomography and visual field examination.Hemodynamic changes play an important role in the pathophysiology of glaucomatous optic nerve damage, however, blood flow evaluation of the optic disc has been directed to large vessels in the past, and there has been no good evaluation equipment for quantitative evaluation of blood flow in microvessels.Optical coherence tomography angiography quantifies blood flow in the retina and choroid, which provides a new method and index for the evaluation of glaucomatous optic nerve damage.In this paper, the application of optical coherence tomography angiography in the measurement of blood vessel density in the optic disc and macular region in the diagnosis and progress assessment of glaucoma, and the consistency of blood flow parameters with structural parameters such as the optic nerve fiber layer and sieve plate and visual field parameters, etc.were reviewed to evaluate the value of blood flow parameters in predicting and assessing glaucomatous damage.

Key words:

Optical coherence tomography angiography; Glaucoma; Evaluation indexes

Contributor Information

Zhang Yang
The Second Affiliated Hospital of Harbin Medical University, Harbin 150001, China
Li Yuanyuan
The Second Affiliated Hospital of Harbin Medical University, Harbin 150001, China
Yuan Huiping
The Second Affiliated Hospital of Harbin Medical University, Harbin 150001, China
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Updated: April 14, 2021 — 8:02 am