Recent advance in vitreous substitutes

Authors:Jiang Feng,  Yan Hua
DOI: 10.3760/cma.j.issn.2095-0160.2016.04.020
Published 2016-04-10
Cite as Chin J Exp Ophthalmol, 2016,34(4): 380-384.

Abstract

In complicated vitreoretinal surgery, vitreous substitutes play a major role in maintaining intraocular pressure.Air, expansion gases, perfluorocarbons liquid, and silicone oil are frequently used in modern vitreoretinal surgery.Long-term vitreous substitute has been attempted with collagen, hyaluronic acid, natural hydrogel polymers and so on.However, an ideal vitreous substitute is being requested for a long time.This review focused on the currently available vitreous substitutes, as well as those in the experimental phase.These compounds were classified based on their functionality, composition, and properties.The clinical use, advantages, and shortcomings of the various substitutes were discussed.Finally, the criteria for an ideal vitreous substitute was defined.

Key words:

Vitreous substitutes; Hydrogel; Vitreous body/surgery

Contributor Information

Jiang Feng
Department of Ophthalmology, General Hospital of Tianjin Medical University, Tianjin 300052, China
Yan Hua
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Updated: October 9, 2019 — 4:14 am