Advance in animal model and pharmacological research for diabetic retinopathy

Authors: He Miao,  Pi Rongbiao,  Huang Wenyong
DOI: 10.3760/cma.j.issn.2095-0160.2015.01.019
Published 2015-01-10
Cite as Chin J Exp Ophthalmol, 2015,33(1): 87-92.

Abstract                              [Download PDF] [Read Full Text]

Diabetes mellitus belongs to metabolic disorder. Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus with the prevalence of 24%-70%. It severely affects the quality of life. DR is bound to a serious problem of public health along with a dramatic aging population and a growing crowd with diabetic mellitus. Even though various pathogenesis of DR have been identified, such as vascular pathological changes, neuronal degeneration, inflammatory lesions, its mechanism remains mystery. A lot of drugs for DR have been developed basing on different pathogenesis mechanisms. Current researches on animal models and pharmacology for DR were reviewed.

Key words:

Diabetic mellitus/complication; Retinopathy; Animal model; Pharmacology

Contributor Information

He Miao
Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen University, Guangzhou 510060, China
Pi Rongbiao
Huang Wenyong
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