Advances in Descemet membrane endothelial keratoplasty

Authors: Wang Wei,  Li Guigang,  Tseng Scheffer C. G.

DOI: 10.3760/cma.j.cn115989-20190616-00263
Published 2021-02-10
Cite as Chin J Exp Ophthalmol, 2021,39(02): 149-153.

Abstract

With relatively low rejection rate and better visual prognosis, Descemet membrane endothelial keratoplasty (DMEK) has become the mainstream surgery for the treatment of endothelial dysfunction in some developed countries, but it has not been applied widely in China due to technical difficulties, the long learning curve, shallow anterior chamber of Chinese people, and the fact that domestic corneal endothelial lesions are often accompanied with other complex eye diseases.In this review, the indications, donor graft preparation including donor selection, graft preparation techniques and visualization of graft, key surgical techniques including the implantation, unwrapping and positioning of graft, postoperative complications including graft detachment, high intraocular pressure, rejection, endothelial cell loss, graft survival rate, and visual prognosis of DMEK were reviewed.

Key words:

Descemet membrane endothelial keratoplasty; Corneal endothelial keratoplasty; Corneal endothelial decompensation

Contributor Information

Wang Wei
Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
Li Guigang
Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
Tseng Scheffer C. G.
R&D Department, Tissue Tech., Inc., Ocular Surface Center, and Ocular Surface Research & Education Foundation, Miami, FL, 33126, USA
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Updated: February 4, 2021 — 1:16 am