Category: 2021, No. 02

Evolution and outlook of dry eye pharmatheutical research

Authors: Mingwu Wang,  Yu Li DOI: 10.3760/cma.j.cn115989-20200204-00049 Published 2021-02-10 Cite as Chin J Exp Ophthalmol, 2021,39(02): 97-101. 【Read Full Text】    【Download PDF】 Abstract Dry eye is a common, highly prevalent and multifactorial ocular disease.Severe dry eye not only has a serious impact on the patient’s work performance and quality of life, but also increases […]

Protocol for the rapid quantitative analysis of neutrophils in mouse cornea by flow cytometry

Authors: Xue Yunxia,  Liu Jun,  Li Zhijie DOI: 10.3760/cma.j.cn115989-20200429-00297 Published 2021-02-10 Cite as Chin J Exp Ophthalmol, 2021,39(02): 102-106. Abstract Objective To provide a standard protocol for the rapid quantitative analysis of neutrophils in inflamed corneas with flow cytometry. Methods The corneal epithelium layer of 15 C57BL/6 mice (6-8 weeks old) was mechanically scraped off […]

Establishment and evaluation of a recurrent infection model of herpes simplex keratitis in BALB/c mice

Authors: Xiao Shuyu,  Yu Ying,  Tao Jinhua DOI: 10.3760/cma.j.cn115989-20191210-00535 Published 2021-02-10 Cite as Chin J Exp Ophthalmol, 2021,39(02): 107-112. Abstract Objective To explore the establishment and evaluation method of recurrent infection model of herpes simplex keratitis (HSK). Methods To determine the optimal duration of the ultraviolet light irradiation, 12 healthy BALB/c mice were randomized into […]

Biocompatibility of fibrin sealant and human corneal fibroblasts

Authors: Ye Qing,  Jiang Linzhi,  Chen Wenlin,  Zhang Wei,  Zeng Jing DOI: 10.3760/cma.j.cn115989-20190605-00244 Published 2021-02-10 Cite as Chin J Exp Ophthalmol, 2021,39(02): 113-118. Abstract Objective To study the biocompatibility of fibrin sealant (FS) and human corneal fibroblasts (HCFs) obtained by small incision lenticule extraction (SMILE). Methods The human corneal stromal tissues were selected from corneal […]

Comparison of fluorescence staining and periodic acid-Schiff staining in the diagnosis of fungal keratitis

Authors: Du Man,  Zhang Li,  Li Peng,  Qi Hongmei,  Lu Xiuhai DOI: 10.3760/cma.j.cn115989-20190702-00284 Published 2021-02-10 Cite as Chin J Exp Ophthalmol, 2021,39(02): 119-125. Abstract Objective To compare the effect of fluorescence staining and periodic acid-Schiff staining in the diagnosis of fungal keratitis (FK). Methods A total of 147 corneal specimens from 147 FK patients treated […]

Comparison of the effective optical zone after small incision lenticule extraction measured by corneal topography and modulation transfer function in myopia

Authors: Hou Jie,  Lei Yulin,  Rao Feng,  Zhang Jing,  Wang Yan DOI: 10.3760/cma.j.cn115989-20201120-00785 Published 2021-02-10 Cite as Chin J Exp Ophthalmol, 2021,39(02): 126-132. Abstract Objective To measure the effective optical zone (EOZ) after small incision lenticule extraction (SMILE) by using corneal topographic map and modulation transfer function (MTF), and to analyze the related factors affecting […]

Relationship between contact lens-related dry eye and morphological changes of meibomian glands

Authors: Liu Zhuzhu,  Wei Ruihua,  Wang Di,  Wang Xiu,  Zhang Rui DOI: 10.3760/cma.j.cn115989-20190329-00153 Published 2021-02-10 Cite as Chin J Exp Ophthalmol, 2021,39(02): 133-138. Abstract Objective To explore the relationship between contact lens (CL) related dry eye and morphological changes of meibomian glands. Methods A cross-sectional study was performed.A total of 157 consecutive subjects (314 eyes) […]

Morphological analysis of meibomian glands in patients with meibomian gland cyst under in vivo confocal microscope

Authors: Cai Jianhao,  Xu Cangeng,  Zhou Lingling,  Zhao Zifeng,  Li Zeyi,  Zhou Yuansheng DOI: 10.3760/cma.j.cn115989-20200303-00135 Published 2021-02-10 Cite as Chin J Exp Ophthalmol, 2021,39(02): 139-143. Abstract Objective To analyze the morphological changes and features of meibomian gland in patients with meibomian gland cyst under in vivo confocal microscope (IVCM). Methods A cross-sectional study was performed.A […]

Treatment of corneal perforation with lamellar keratoplasty combined with autogenous corneal stromal padding

Authors: Wang Lulu,  Zhang Yueqin,  Yu Xiaofei,  Cai Ruizhen DOI: 10.3760/cma.j.cn115989-20190927-00418 Published 2021-02-10 Cite as Chin J Exp Ophthalmol, 2021,39(02): 144-148. Abstract [Read Full Text]   [Download PDF] Objective To study the clinical outcome of lamellar keratoplasty combined with autogenous corneal stromal padding for treatment of corneal perforation. Methods An observational case series study was conducted.A […]

Advances in Descemet membrane endothelial keratoplasty

Authors: Wang Wei,  Li Guigang,  Tseng Scheffer C. G. DOI: 10.3760/cma.j.cn115989-20190616-00263 Published 2021-02-10 Cite as Chin J Exp Ophthalmol, 2021,39(02): 149-153. Abstract With relatively low rejection rate and better visual prognosis, Descemet membrane endothelial keratoplasty (DMEK) has become the mainstream surgery for the treatment of endothelial dysfunction in some developed countries, but it has not […]