Application of optical coherence tomography angiography in optic nerve diseases

Authors: Liu Xiaorong,  Chen Fang
DOI: 10.3760/cma.j.cn115989-20200427-00290
Published 2022-12-10
Cite as Chin J Exp Ophthalmol, 2022, 40(12): 1208-1213.

Abstract                              [View PDF] [Read Full Text]

Optical coherence tomography angiography (OCTA) can be used to obtain retinal and choroidal blood flow images of optic disc and macular area, and evaluate the vascular morphology and blood perfusion of different layers in different areas of optic disc and macular area.It provides rich possibilities for the description and quantification of optic nerve diseases, the exploration of disease pathogenesis, and the development and evaluation of new treatments.In recent years, OCTA has played an important role in the diagnosis and treatment of optic nerve diseases.It is helpful in the diagnosis of optic neuritis, ischemic optic neuropathy, papilledema secondary to idiopathic intracranial hypertension, and to some extent to evaluate the visual function of affected eyes.The vascular morphology and quantitative analysis of the optic disc and macular area by OCTA may be of value in discriminating optic disc swelling from various etiologies and different types of anterior ischemic optic neuropathy, and facilitate further exploration of the pathogenesis of optic nerve diseases.This article reviewed the application status, recent progress and limitations of OCTA in the diagnosis, differential diagnosis and pathogenesis of optic nerve diseases.OCTA is still not in the stage of meaningful clinical use in neuro-ophthalmology, but its application can be wider as there are more meaningful researches and findings.

Key words:

Optic nerve diseases; Tomography, optical coherence, angiography; Diagnosis, differential

Contributor Information

Liu Xiaorong

Department of Ophthalmology, Subei People’s Hospital Affiliated to Yangzhou University, Yangzhou 225001, China

Chen Fang

Department of Ophthalmology, Subei People’s Hospital Affiliated to Yangzhou University, Yangzhou 225001, China

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