Category: 2019, No. 01

Current advance of polypoidal choroidal vasculopathy in diagnosis and treatment

Authors: Zhou Nan,  Wei Wenbin DOI: 10.3760/cma.j.issn.2095-0160.2019.01.017 Published 2019-01-10 Cite as Chin J Exp Ophthalmol, 2019,37(1): 77-80. Abstract Polypoidal choroidal vasculopathy (PCV) is a kind of fundus disease characterized by choroidal anomalous branch vascular network and terminal polypoidal dilatation.The pathological basis of idiopathic choroidal neovascularization is similar to age-related macular degeneration (AMD). It is controversial that whether […]

Design and technical challenge of retinal prosthesis

Authors: Chen Bichi,  Lyu Fan DOI: 10.3760/cma.j.issn.2095-0160.2019.01.016 Published 2019-01-10 Cite as Chin J Exp Ophthalmol, 2019,37(1): 73-76. Abstract Retinitis pigmentosa (RP) is a kind of hereditary disease characterized by progressive photoreceptor and pigmented epithelial cell dysfunction.It is also a common cause of blindness worldwide.In recent years, gene therapy, neurotrophic therapy, stem cell therapy and other methods for […]

Role and mechanism of Müller cells in retinal injury

Authors:  Shi Xueying,  Li Xiaorong DOI: 10.3760/cma.j.issn.2095-0160.2019.01.015 Published 2019-01-10 Cite as Chin J Exp Ophthalmol, 2019,37(1): 69-72. Abstract In mammalian retina, Müller cells are dominating macroglial cells and span the entire retina.These cells perform a variety of physiological roles to maitain the normal function of retina.However, Müller cells become’reactivity’in response to every pathological changes in the retina.Reactive […]

Treatment of wet age-related macular degeneration: Now and future

Authors:  Ding Xiaoyan,  Wang Zhirong,  Sun Limei DOI: 10.3760/cma.j.issn.2095-0160.2019.01.014 Published 2019-01-10 Cite as Chin J Exp Ophthalmol, 2019,37(1): 63-68. Abstract Wet age-related macular degeneration (AMD), which is the leading cause of visual impairment in elderly people, significantly affects quality of life of millions worldwide.Currently, anti-VEGF is the first-line therapy for wAMD, bringing encouraging results in improving the vision.However, […]

Recent developments in neuro-ophthalmology

Authors:  Cheng Zhang DOI: 10.3760/cma.j.issn.2095-0160.2019.01.013 Published 2019-01-10 Cite as Chin J Exp Ophthalmol, 2019,37(1): 55-62. Abstract Some recent advances in neuro-ophthalmology including clinical trials, diagnostic testing and newly elucidated disease entitites were summarized in present paper, such as neuromyelitis optica spectrum disorder.The review goes into great detail regarding recent clinical trials in neuro-ophthalmology.These trials have investigated […]

Effects of internal limiting membrane peeling during macular hole surgery on retinal anatomical and functional outcomes

Authors: He Qingyi,  Xie Zhenggao DOI: 10.3760/cma.j.issn.2095-0160.2019.01.012 Published 2019-01-10 Cite as Chin J Exp Ophthalmol, 2019,37(1): 51-54. Abstract Idiopathic macular hole (IMH) refers to full thickness defects of retinal neuroepithelial layer in macular area without clear reasons, and the combination of pars plana vitrectomy (PPV) with internal limiting membrane peeling (ILMP) is a standard procedure for macular […]

Treatment of idiopathic macular hole: internal limiting membrane peeling or inverted internal limiting membrane flap

Authors: Liu Guangfeng,  Jiang Yanrong DOI: 10.3760/cma.j.issn.2095-0160.2019.01.011 Published 2019-01-10 Cite as Chin J Exp Ophthalmol, 2019,37(1): 49-50. Abstract Surgical management of idiopathic macular hole (IMH) is a hot topic in the field of fundus disease, and its classical surgery is internal limiting membrane peeling.In recent years, many researchers explored inverted internal limiting membrane flap technique for IMH.However, […]

Therapeutic effects of flute-needle vacuum assistant hole closure technique for large idiopathic macular hole

Authors: Liu Guangfeng,  Ma Zhizhong,  Ma Lie,  Jiang Yanrong DOI: 10.3760/cma.j.issn.2095-0160.2019.01.010 Published 2019-01-10 Cite as Chin J Exp Ophthalmol, 2019,37(1): 45-48. Abstract Objective To evaluate the therapeutic effects of flute-needle vacuum assistant hole closure technique for large idiopathic macular hole (IMH). Methods The clinical data of 25 eyes with IMH of 408-939 μm in 23 patients who received pars […]

Prevalence and risk factors of age-related macular degeneration in Uyghur residents aged 50 or above in southern Xinjiang region

Authors: Liu Jiawen,  Lou Bingsheng,  Li Yao,  Chen Xueyi DOI: 10.3760/cma.j.issn.2095-0160.2019.01.009 Published 2019-01-10 Cite as Chin J Exp Ophthalmol, 2019,37(1): 40-44. Abstract Objective To investigate the prevalence and risk factors of age-related macular degeneration (AMD) in southern Xinjiang Uyghur residents aged≥ 50 years. Methods A cross-sectional study was carried out.Randomized cluster sampling was used in this survey of Uyghur […]

Relationship of mean retinal sensitivity with vision-related quality of life in patients with idiopathic macular hole

Authors: Wang Zengyi,  Liang Xida,  Yu Yanping,  Wang Jing,  Liu Wu DOI: 10.3760/cma.j.issn.2095-0160.2019.01.008 Published 2019-01-10 Cite as Chin J Exp Ophthalmol, 2019,37(1): 35-39. Abstract Objective To evaluate the relationship of retinal sensitivity (MS) with vision-related quality of life in patients with idiopathic macular hole (IMH). Methods A prospective cohort study was performed in this study.Thirty-one monocular IMH patients were enrolled […]