Category: 2019

Analysis of differentially expressed genes of Staphylococcus aureus isolated from corneal ulcer and healthy conjunctival sac

Authors:Liu Qing,  Dong Yanling,  Huang Yusen DOI: 10.3760/cma.j.issn.2095-0160.2019.09.003 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 701-706. Abstract                              [View PDF] [Read Full Text] Objective To investigate the possible pathogenesis of Staphylococcus aureus (S.aureus) corneal ulcer by analyzing the differentially expressed genes (DEGs) of S.aureus isolated from the patients with […]

Proteomic research of human retinal microvascular pericytes stimulated with high glucose

Authors:Xiao Mengran,  Zhang Xiaomin,  Shao Xianfeng,  Xiao Jing,  Yang Fuhua,  Zhang Hui,  Ea Vicki L,  Li Xiaorong DOI: 10.3760/cma.j.issn.2095-0160.2019.09.004 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 707-712. Abstract                               [View PDF] [Read Full Text] Objective To determine the changes of protein expressions in human retinal […]

Effect and potential signaling pathway of hedgehog protein on the function of human retinal microvascular endothelial cell

Authors:Li Yang,  Hu Qinrui,  Wang Bin,  Xia Huika,  Zhang Xiaohu DOI: 10.3760/cma.j.issn.2095-0160.2019.09.005 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 713-718. Abstract                              [View PDF] [Read Full Text] Objective To explore the impact of Hedgehog protein on human retinal microvascular endothelial cell(HRMEC)and its signaling pathway. Methods […]

Diagnosis of choroideremia in two Chinese families misdiagnosed as retinitis pigmentosa using next-generation sequencing

Authors:Wang Miaomiao,  Wang Zhuoshi,  Sun Yan,  Xia Yang,  He Wei DOI: 10.3760/cma.j.issn.2095-0160.2019.09.006 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 719-724. Abstract                               [View PDF] [Read Full Text] Objective To identify choroideremia and retinitis pigmentosa(RP)using next-generation sequencing(NGS)technology. Methods A cross-sectional study was adopted.The participants were two […]

Mutations analysis of FRMD7 gene in idiopathic congenital nystagmus families

Authors:Du Wei,  Zhang Ye,  Xie Zhenggao DOI: 10.3760/cma.j.issn.2095-0160.2019.09.008 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 726-729. Abstract                              [View PDF] [Read Full Text] Objective To reveal the pathogenic mutations in Chinese families with idiopathic congenital nystagmus(ICN) Methods Six families with ICN were recruited from Subei […]

Clinical manifestation and gene mutation of Bietti crystalline corneoretinal dystrophy

Authors:Guo Tong,  Jia Ruixuan,  Chen Ningning,  Yang Liping DOI: 10.3760/cma.j.issn.2095-0160.2019.09.009 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 730-735. Abstract                               [View PDF] [Read Full Text] Objective To analyze the clinical manifestation and CYP4V2 mutations of Bietti crystalline corneoretinal dystrophy( BCD) families. Methods Total […]

Mutation screen of P4HA2 gene in Tujia high myopia patients

Authors:Yang Lin,  Li Tuo,  Cai Xiaojun,  Ke Min,  Chen Zhongshan DOI: 10.3760/cma.j.issn.2095-0160.2019.09.010 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 736-739. Abstract                              [View PDF] [Read Full Text] Objective To investigate the mutation of P4HA2 gene in Tujia high myopia patients. Methods Clinical data […]

Screening of pathogenic mutation in a Chinese family with congenital pulverulent cataract

Authors:Ji Kangkang,  Gu Zhengyu,  Wang Yaru,  Bao Weili,  Liao Rongfeng DOI: 10.3760/cma.j.issn.2095-0160.2019.09.011 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 740-744. Abstract                               [View PDF] [Read Full Text] Objective To analysis the pathogenic mutation and the clinical characteristics of a three generation family with congenital pulverulent […]

Measurement of biological parameters of nanophthalmos and its correlation with axial length

Authors:Wei Wei,  Xiao Hui,  Chen Liming,  Luo Jingyi,  Fang Lei,  Lin Shufen,  Liu Xing DOI: 10.3760/cma.j.issn.2095-0160.2019.09.012 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 745-749. Abstract                               [View PDF] [Read Full Text] Objective To quantitatively measure biological parameters of nanophthalmos and analyze the correlation between axial […]

Gene mutation spectrum analysis of retinitis pigmentosa patients in Ningxia Region of China

Authors:Rong Weining,  Qi Rui,  Wang Xiaoguang,  Fang Xinhe,  Sheng Xunlun DOI: 10.3760/cma.j.issn.2095-0160.2019.09.013 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 750-754. Abstract                               [View PDF] [Read Full Text] Objective To analysis the gene mutation spectrum of retinitis pigmentosa (RP) patients in Ningxia Region of China. Methods […]