Authors: Liu Dongmei, Li Junhong DOI: 10.3760/cma.j.issn.2095-0160.2015.09.009 Published 2015-09-10 Cite as Chin J Exp Ophthalmol, 2015,33(9): 811-815. Abstract [Download PDF] [Read Full Text] Background The primary pathologic mechanism of posterior capsular opacification (PCO) is proliferation, migration and epithelial-mesenchymal transformation of residuary lens […]
Category: 2019, No. 09
Focus on the treatment of inherited retinal diseases
Author:Pang Jijing DOI: 10.3760/cma.j.issn.2095-0160.2019.09.001 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 689-693. Abstract [View PDF] [Read Full Text] Inherited retinal diseases (IRDs) are rare and incurable eye diseases.Gene therapy has become a new method for the treatment of IRDs.At present, at least 26 clinical […]
Differentially expressed genes analysis of retinal vascular endothelial cells under hyperglycemia and hyperlipidemia induced by α-melanocyte-stimulating hormone
Authors:Wu Mianmian, Guo Fang, Li Yahong, Liu Ke, Zhang Yan DOI: 10.3760/cma.j.issn.2095-0160.2019.09.002 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 694-700. Abstract [View PDF] [Read Full Text] Objective To investigate the effect of α-melanocyte-stimulating hormone(α-MSH) on the expression of mRNA and long noncoding RNA (lncRNA) […]
Analysis of differentially expressed genes of Staphylococcus aureus isolated from corneal ulcer and healthy conjunctival sac
Authors:Liu Qing, Dong Yanling, Huang Yusen DOI: 10.3760/cma.j.issn.2095-0160.2019.09.003 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 701-706. Abstract [View PDF] [Read Full Text] Objective To investigate the possible pathogenesis of Staphylococcus aureus (S.aureus) corneal ulcer by analyzing the differentially expressed genes (DEGs) of S.aureus isolated from the patients with […]
Proteomic research of human retinal microvascular pericytes stimulated with high glucose
Authors:Xiao Mengran, Zhang Xiaomin, Shao Xianfeng, Xiao Jing, Yang Fuhua, Zhang Hui, Ea Vicki L, Li Xiaorong DOI: 10.3760/cma.j.issn.2095-0160.2019.09.004 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 707-712. Abstract [View PDF] [Read Full Text] Objective To determine the changes of protein expressions in human retinal […]
Effect and potential signaling pathway of hedgehog protein on the function of human retinal microvascular endothelial cell
Authors:Li Yang, Hu Qinrui, Wang Bin, Xia Huika, Zhang Xiaohu DOI: 10.3760/cma.j.issn.2095-0160.2019.09.005 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 713-718. Abstract [View PDF] [Read Full Text] Objective To explore the impact of Hedgehog protein on human retinal microvascular endothelial cell(HRMEC)and its signaling pathway. Methods […]
Diagnosis of choroideremia in two Chinese families misdiagnosed as retinitis pigmentosa using next-generation sequencing
Authors:Wang Miaomiao, Wang Zhuoshi, Sun Yan, Xia Yang, He Wei DOI: 10.3760/cma.j.issn.2095-0160.2019.09.006 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 719-724. Abstract [View PDF] [Read Full Text] Objective To identify choroideremia and retinitis pigmentosa(RP)using next-generation sequencing(NGS)technology. Methods A cross-sectional study was adopted.The participants were two […]
Mutations analysis of FRMD7 gene in idiopathic congenital nystagmus families
Authors:Du Wei, Zhang Ye, Xie Zhenggao DOI: 10.3760/cma.j.issn.2095-0160.2019.09.008 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 726-729. Abstract [View PDF] [Read Full Text] Objective To reveal the pathogenic mutations in Chinese families with idiopathic congenital nystagmus(ICN) Methods Six families with ICN were recruited from Subei […]
Clinical manifestation and gene mutation of Bietti crystalline corneoretinal dystrophy
Authors:Guo Tong, Jia Ruixuan, Chen Ningning, Yang Liping DOI: 10.3760/cma.j.issn.2095-0160.2019.09.009 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 730-735. Abstract [View PDF] [Read Full Text] Objective To analyze the clinical manifestation and CYP4V2 mutations of Bietti crystalline corneoretinal dystrophy( BCD) families. Methods Total […]
Mutation screen of P4HA2 gene in Tujia high myopia patients
Authors:Yang Lin, Li Tuo, Cai Xiaojun, Ke Min, Chen Zhongshan DOI: 10.3760/cma.j.issn.2095-0160.2019.09.010 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 736-739. Abstract [View PDF] [Read Full Text] Objective To investigate the mutation of P4HA2 gene in Tujia high myopia patients. Methods Clinical data […]