Tag: Glaucoma

New paradigms of immune regulation in glaucoma during the whole clinical process

Authors: Wu Jian,  Su Wenru,  Zhuo Yehong DOI: 10.3760/cma.j.cn115989-20220314-00104 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 289-293. Abstract Glaucoma is an irreversible blinding eye disease caused by the structural and functional damage of optic nerve induced by pathological increase of intraocular pressure (IOP), characterized by multiple causes and strong heterogeneity.The control of IOP […]

Inhibitory effect of CLC-2 chloride channel targeted blocking on fibrosis of human conjunctival fibroblasts

Authors: Wu Sharengaowa,  Cui Renzhe,  Lu Di,  Ding Haoxuan,  Sun Lixia DOI: 10.3760/cma.j.cn115989-20200609-00410 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 294-302. Abstract Objective To investigate the inhibitory effect of CLC-2 chloride channel targeted blocking on fibrosis of human conjunctival fibroblasts (HConF). Methods HConF were divided into blank control group, lipofectamine 2000 (Lipo2000) group, […]

Inhibitory effect of ILK-siRNA-AAV on scar formation after glaucoma filtering surgery in rats

Authors: Xing Yao,  Wang Jianming,  Fan Yazhi,  Xiong Lei,  Wang Wenjing,  Cui Lijun DOI: 10.3760/cma.j.cn115989-20210617-00362 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 316-325. Abstract Objective To investigate the role of integrin-linked kinase (ILK)-small interfering RNA (siRNA)-adeno-associated virus (AAV) in scar formation after glaucoma filtering surgery in rat eyes. Methods Forty-eight Sprague Dawley rats […]

Normal tension glaucoma: reconsideration and reevaluation

Authors: Fan Ning,  Wang Yun,  Tan Junkai,  Wang Ningli,  Liu Xuyang DOI: 10.3760/cma.j.cn115989-20210712-00408 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 345-350. Abstract Normal tension glaucoma (NTG) is almost the most difficult type of glaucoma to diagnose.The difficulty lies in the lack of specificity of the symptoms and signs of glaucomatous optic neuropathy (GON), […]

Research progress of intraocular pressure and its related influencing factors in children

Authors: Han Fang,  Wang Yan DOI: 10.3760/cma.j.cn115989-20200811-00581 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 351-356. Abstract Glaucoma is an irreversible cause of blindness, and elevated intraocular pressure (IOP) is an important risk factor for it.There is no clearly defined value of ocular hypertension in children, thus the accurate evaluation of IOP in children […]

Research progress in ultrasound cycloplasty for the treatment of glaucoma

Authors: Meng Sukun,  Xu Ke,  Zhang Chun DOI: 10.3760/cma.j.cn115989-20200213-00069 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 357-360. Abstract Surgery to destroy the ciliary body is an effective means to reduce the intraocular pressure in glaucoma.Ultrasound cycloplasty (UCP) is a computer-aided automatic operation that produces high-intensity focused ultrasound to induce ciliary body coagulation through […]

Application of artificial intelligence in ophthalmic optical coherence tomography

Authors: Duan Kairui,  Zhang Hong DOI: 10.3760/cma.j.cn115989-20191231-00566 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 83-87. Abstract Artificial intelligence (AI) has become the forefront of research in computer science, which has been widely used in the medical field. Ophthalmology is a discipline highly dependent on imaging inspection. AI has great advantages in image recognition.The […]