Category: Clinical Science

Association of ABCA1 rare nonsynonymous variants with primary open angle glaucoma

Authors: Xu Yuxia,  Huang Lulin,  Gong Bo,  Chen Yuhong,  Sun Xinghuai,  Yang Zhenglin DOI: 10.3760/cma.j.issn.2095-0160.2019.06.007 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 439-445. Abstract                              [View PDF] [Read Full Text] Objective To explore the rare nonsynonymous variants of ABCA1 gene in primary open angle glaucoma (POAG). Methods A prospective cohort […]

Analysis of GJA3 mutation associated with a Chinese family with autosomal dominant congenital cataract by whole-exome sequencing

Authors:Liu Yuying,  Wan Wencui,  Yang Ge,  Pang Xuena,  Yang Guoguo,  Jin Xuemin DOI: 10.3760/cma.j.issn.2095-0160.2016.10.011 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 916-919. Abstract                              [Download PDF] [Read Full Text] Congenital cataract is one of the important reasons for the blindness of children, and most congenital […]

Association of Gly82Ser polymorphism of RAGE gene with diabetic retinopathy in Han people with type 2 diabetes of Wuxi region

Authors:Cao Jia,  Yao Yong,  Xie Tianhua,  Gu Zheyao,  Zou Jian DOI: 10.3760/cma.j.issn.2095-0160.2016.10.009 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 910-914. Abstract                           [Download PDF] [Read Full Text] Background Receptor for advanced glycation end products (RAGE) play an important role in the process of type 2 diabetes […]

Screening of TYR gene mutations and clinical classification in oculocutaneous albinism patients

Authors:Wang Liming,  Han Ruifang,  Ying Ming,  Hao Peng,  Li Ningdong DOI: 10.3760/cma.j.issn.2095-0160.2016.10.008 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 905-909. Abstract                              [Download PDF] [Read Full Text] Background Oculocutaneous albinism (OCA) is a hereditary disease of pigment absence in eyes, skin […]

Mutation analysis of Pax6 in Chinese patients with congenital aniridia

Authors:Hao Peng,  Ying Ming,  Han Ruifang,  Wang Liming,  Li Ningdong DOI: 10.3760/cma.j.issn.2095-0160.2016.10.007 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 900-904. Abstract                               [Download PDF] [Read Full Text] Background Congenital aniridia is a rare congenital autosomal dominant disease, which is shown as aniridia of double eyes, […]

Identification of genetic mutation in a Chinese pedigree with congenital cataract by whole-exome sequencing

Authors:Bu Juan,  Liu Jing,  Pang Honglei,  Liu Feng,  Wang Lejin DOI: 10.3760/cma.j.issn.2095-0160.2016.10.006 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 896-899. Abstract                            [Download PDF] [Read Full Text]  Background Genetic mutation remains to be the most common cause of congenital cataract.Whole exon sequencing technology is an ideal […]

A 5-year prospective study of type 2 diabetes patients in Shanghai Xinjing Community 3.The regression and promoting factors of diabetic retinopathy and diabetic macular edema in Chinese type 2 diabetes patients

Authors:Jin Peiyao,  Peng Jinjuan,  Zou Haidong,  Xu Xun,  Zhang Xi,  Wang Weiwei,  Fu Jiong,  Bai Xuelin DOI: 10.3760/cma.j.issn.2095-0160.2016.11.014 Published 2016-11-10 Cite as Chin J Exp Ophthalmol, 2016,34(11): 1025-1030. Abstract                              [Download PDF] [Read Full Text] Background Long-term study on type 2 diabetes discovered that some patients with diabetic retinopathy (DR) or diabetic macular edema (DME) appear […]

A meta-analysis of selective laser trabeculoplasty versus antiglaucomatous medication for glaucomatous and ocular hypertensive eyes

Authors:Wei Yahui,  Li Xueying,  Cai Yu DOI: 10.3760/cma.j.issn.2095-0160.2016.11.013 Published 2016-11-10 Cite as Chin J Exp Ophthalmol, 2016,34(11): 1019-1024. Abstract                              [Download PDF] [Read Full Text] Background Selective laser trabeculoplasty (SLT) and antiglaucomatous medications can be used to treat both glaucoma and ocular hypertension.However, which is more effective […]

Morphological and functional changes of ocular surface and meibomian glands in perimenopausal syndrome in meibomian gland dysfunction

Authors:Yang Liu,  Hou Haiyan,  Meng Zhu,  Zhao Jinrong,  Zhao Shaozhen DOI: 10.3760/cma.j.issn.2095-0160.2016.11.012 Published 2016-11-10 Cite as Chin J Exp Ophthalmol, 2016,34(11): 1014-1018. Abstract                              [Download PDF] [Read Full Text] Background Perimenopausal syndrome (PMS) which changes in physiology, pathology and hormone levels, brings a series of ocular and systemic health problems, such as dry […]

Comparison of therapeutic effects between a new warm moist air device assisted with eyelid massage and eyedrops with only eyedrops for meibomian gland dysfunction

Authors:Zhao Bing,  Zhang Xiaolin,  Sun Liqun,  Zhang Xiaobo DOI: 10.3760/cma.j.issn.2095-0160.2016.11.011 Published 2016-11-10 Cite as Chin J Exp Ophthalmol, 2016,34(11): 1009-1013. Abstract                              [Download PDF] [Read Full Text] Background Meibomian gland dysfunction (MGD) is a common eye disease that leads to ocular surface damage.Conventional treating method is hot compress with heating pads or […]