Category: 2016, No. 10

Clinical phenotype and maternal mutation analysis of Leber hereditary optic neuropathy

Authors:Huang Lyuzhen,  Li Tianqi,  Wang Bin,  Li Xiaoxin DOI: 10.3760/cma.j.issn.2095-0160.2016.10.012 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 920-924. Abstract Background Leber hereditary optic neuropathy (LHON) is a maternally inherited disease caused by mitochondrial DNA (mtDNA) mutation with the common mutation sites of m. 3460 G>A, m.11778 G>A and m. 14484 T>C, and other mutation […]

Changes of ocular aberration stability after correction with adaptive optics system

Authors:Chen Xiaoqin,  Wang Yan,  Jiang Yanglin,  Dai Yun,  Zhao Haoxin,  Zhang Yudong DOI: 10.3760/cma.j.issn.2095-0160.2016.10.017 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 941-946. Abstract Background The use of adaptive optics (AO) system in ophthalmic clinic and basic studies has increased in recent years.However, there are few reports on the stability of ocular aberrations after correction. […]

Recent advances in the etiology of Posner-Schlossman syndrome

Authors:Sun Yanran,  Dang Yalong,  Zhang Chun DOI: 10.3760/cma.j.issn.2095-0160.2016.10.020 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 957-960. Abstract Posner-Schlossman syndrome (PSS) or glaucomatocyclitic crisis is a rare, unilateral recurrent inflammatory ocular hypertensive disease.Although it is typically self-limited and has benign prognosis, some cases were reported with advanced optic nerve cupping and associated visual field loss.Current […]

Advance in gene therapy of ocular disease

Authors:Lyu Juling,  Xing Yiqiao,  Shen Yin DOI: 10.3760/cma.j.issn.2095-0160.2016.10.019 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 952-956. Abstract Currently, 31 clinical trials have been approved, most of them are still in progress.Leber congenital amaurosis (LCA) has been conducted to phase Ⅲ clinical trials, the longest follow-up time was 6 years.A multicenter clinical trial about choroideremia […]

Analysis of risk factors of diabetic retinopathy inpatients with type 2 diabetes in the city of Dongguan

Authors:Chen Shuhui,  Zhang Min,  Meng Qianli,  Guo Haike,  Liu Qingyang,  Cui Ying DOI: 10.3760/cma.j.issn.2095-0160.2016.10.018 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 947-951. Abstract Background Diabetic retinopathy (DR) has become the main cause of blindness in the world, But the etiology of DR is still not clear, and the results of the studies on the […]

Changes of ocular aberration stability after correction with adaptive optics system

Authors:hen Xiaoqin,  Wang Yan,  Jiang Yanglin,  Dai Yun,  Zhao Haoxin,  Zhang Yudong DOI: 10.3760/cma.j.issn.2095-0160.2016.10.017 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 941-946. Abstract Background The use of adaptive optics (AO) system in ophthalmic clinic and basic studies has increased in recent years.However, there are few reports on the stability of ocular aberrations after correction. […]

The reproducibility of mechanism categories of angle closure using ultrasound biomicroscopy and anterior segment optical coherence tomography

Authors:Zhang Ye,  Tang Xin,  Wang Ningli DOI: 10.3760/cma.j.issn.2095-0160.2016.10.016 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 936-940. Abstract Background Angle closure is the pathological basis of primary angle-closure disease (PACD). Understanding different types of angle closure mechanisms is significant for evaluation of risk factors, prevention, diagnosis and treatment of PACD.Ultrasound biomicroscopy (UBM) is commonly used […]

Corneal biomechanical properties in different anterior chamber angle of glaucoma

Authors:Du Shaolin,  Huang Wenbin,  Zhang Yichi,  Dennis Lam DOI: 10.3760/cma.j.issn.2095-0160.2016.10.015 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 930-935. Abstract Background Recent studies have demonstrated that glaucoma progression had great relationship with corneal biomechanical properties.However, there are not enough studies about corneal biomechanical properties in different types of glaucoma. Objective This study was to evaluate […]

Effect on macular structure and visual acuity after scleral buckling and pars plana vitrectomy for macula-off rhegmatogenous retinal detachment

Authors:Cui Li,  Jiang Yanrong,  Zhao Mingwei,  Li Xiaoxin DOI: 10.3760/cma.j.issn.2095-0160.2016.10.014 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 926-929. Abstract Background The patients who have undergone successful surgery for retinal detachment (RD) cannot recover their vision quickly, and the reason is not very clearly now. Objective This study was to compare the ellipsoid zone integrity […]

Clinical phenotype and maternal mutation analysis of Leber hereditary optic neuropathy

Authors:Huang Lyuzhen,  Li Tianqi,  Wang Bin,  Li Xiaoxin DOI: 10.3760/cma.j.issn.2095-0160.2016.10.012 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 920-924. Abstract Background Leber hereditary optic neuropathy (LHON) is a maternally inherited disease caused by mitochondrial DNA (mtDNA) mutation with the common mutation sites of m. 3460 G>A, m.11778 G>A and m. 14484 T>C, and other mutation […]