Category: 2019, No. 06

Progress of optical coherence tomography in retinopathy of prematurity

Authors: Liang Chaoqun,  Chen Changzheng DOI: 10.3760/cma.j.issn.2095-0160.2019.06.019 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 493-496. Abstract Retinopathy of prematurity (ROP) is one of the important causes of visual impairment in children.The current diagnosis relies mainly on the wide-field digital retinal imaging system (RetCam) and binocular indirect ophthalmoscopy.In recent years, the applications of handheld optical coherence […]

Advances in corneal endothelial-to-mesenchymal transition

Authors: Lu Qing,  Hong Jing DOI: 10.3760/cma.j.issn.2095-0160.2019.06.018 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 488-492. Abstract Corneal endothelial cells (CECs) are essential for maintenance of corneal transparency.Proliferative potency of human CECs is poor in vivo, so endothelial dysfunction is irreversible.Many studies have showed that CECs are able to proliferate in vitro.However, endothelial to mesenchymal transition […]

Recent progress of high-altitude environment impact on the eyes

Authors: Yang Yiquan,  Wang Ningli DOI: 10.3760/cma.j.issn.2095-0160.2019.06.016 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 481-485. Abstract High-altitude environment has its unique characteristics, which can cause a variety of acute and chronic mountain sicknesses.With increasing human activities at high altitude, the impact of high altitude exposure on human body has become a hotspot.Hypobaric hypoxia, strong breeze, […]

Protective effect of heat shock protein 70 on glaucomatous optic nerve injury

Authors: Chen Di,  Guo Wenyi DOI: 10.3760/cma.j.issn.2095-0160.2019.06.015 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 477-480. Abstract Glaucoma is characterized by progressive loss of vision, which is caused by degeneration of retinal ganglion cells (RGCs). Heat shock proteins (HSP), whose expression could be induced by a variety of stressful stimuli, belong to a superfamily of stress […]

Advances in the application of portable perimetry in glaucoma

Authors: Zhao Can,  Zhong Hua DOI: 10.3760/cma.j.issn.2095-0160.2019.06.014 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 472-476. Abstract Glaucoma is the irreversible blind eye disease and many glaucoma patients have severe optic nerve and visual field defect in their initial diagnosis.Therefore, visual field is critical to the evaluation of glaucoma damage.However, the testing time is too long […]

Clinical observation of microcatheter assisted trabeculotomy on the treatment of childhood glaucoma

Authors: Yang Xiaoyuan,  Wang Huaizhou,  Gao Chuanwen,  Wang Bo,  Li Haijun,  Dong Yangceng  DOI: 10.3760/cma.j.issn.2095-0160.2019.06.013 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 467-471. Abstract Objective To investigate the clinical efficacy and safety of microcatheter assisted trabeculectomy on the treatment of childhood glaucoma. Methods A prospective case series method was performed.Sixteen childhood glaucoma with 22 eyes were enrolled in Henan […]

Distribution of posterior corneal astigmatism and its effect on the calculation of Toric intraocular lens

Authors: Li Panpan,  Wu Jian,  Xue Ying,  Zhou Jing,  Zhang Yujian,  Guan Huaijin DOI: 10.3760/cma.j.issn.2095-0160.2019.06.012 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 460-466. Abstract Objective To analysis the distribution of posterior corneal astigmatism (PA) and evaluate the influence of keratometric astigmatism (KA) and total corneal astigmatism (TCA) on the calculation of Toric intraocular lens (Toric IOL) in patients with […]

Clinical changes of contralateral unaffected eyes in patients with unilateral infectious keratitis under in vivo confocal microscopy

Authors: Liu Xintian,  Zhang Hong,  Jin Xin,  Shi Yan,  Jiang Xue DOI: 10.3760/cma.j.issn.2095-0160.2019.06.011 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 454-459. Abstract Objective To evaluate the clinical changes of corneal epithelial cells, dendritic cells, endothelial cells and corneal nerves in contralateral eyes of patients with unilateral infectious keratitis. Methods A prospective serial case observation study was conducted in […]

Correlation analysis between macular thickness and visual field mean defect in pseudoexfoliation glaucoma

Authors: Li Fan,  Tang Guangxian,  Ma Lihua,  Geng Yulei,  Zhang Hengli,  Yan Xiaowei,  Zhang Qing DOI: 10.3760/cma.j.issn.2095-0160.2019.06.009 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 447-452. Abstract Objective To compare and analyze differences in macular thickness and to discuss the correlation between macular thickness and visual field mean defect (MD) in early and moderate, late pseudoexfoliation glaucoma (PXG) patients and normal […]

Association of ABCA1 rare nonsynonymous variants with primary open angle glaucoma

Authors: Xu Yuxia,  Huang Lulin,  Gong Bo,  Chen Yuhong,  Sun Xinghuai,  Yang Zhenglin DOI: 10.3760/cma.j.issn.2095-0160.2019.06.007 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 439-445. Abstract Objective To explore the rare nonsynonymous variants of ABCA1 gene in primary open angle glaucoma (POAG). Methods A prospective cohort study was carried out.Three hundred and ninety-eight POAG patients and 198 healthy controls matched in […]