Category: Experimental Science

Cytotoxicity research of three non-steroidal anti-inflammatory eye drops in human corneal epithelial cells

Authors: Qu Mingli,  Duan Haoyun,  Wang Yao,  Wang Qian,  Zhou Qingjun DOI: 10.3760/cma.j.issn.2095-0160.2015.07.012 Published 2015-07-10 Cite as Chin J Exp Ophthalmol, 2015,33(7): 627-632. Abstract                              [Download PDF] [Read Full Text] Background Diclofenac sodium eye drops, pranoprofen eye drops and bromfenac sodium hydrate eye […]

Modulation of MEK/ERK and PI3K/Akt pathways to the expression of DDR2 and MMP-13 in choroidal neovascularization

Authors: Yang Xiumei,  Wang Yusheng,  Zhang Jian,  Li Yan,  Yao Libo DOI: 10.3760/cma.j.issn.2095-0160.2015.08.002 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 678-685. Abstract                              [Download PDF] [Read Full Text] Background It is estimated that discoidin domain receptor 2 (DDR2) and matrix metalloproteinase-13 […]

Construction and assessment of recombinant plasmid pRNAT-U6.1/CFB siRNA and its inhibitory effect on proliferation of human umbilical vein endothelial cells

Authors: Tong Huan,  Shang Qingli,  Ma Jingxue,  Gao Jian,  Wang Xin DOI: 10.3760/cma.j.issn.2095-0160.2015.08.003 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 686-690. Abstract                               [Download PDF] [Read Full Text] Background Choroidal neovascularization (CNV) is one of the causes of blindness in multiple […]

Change of serum response factor expression in eyelid of different embryo development stages of B6-Co mice

Authors: Song Hongyan,  Li Yao,  Lu Zeyan,  Wu Liucheng,  Shao Yixiang DOI: 10.3760/cma.j.issn.2095-0160.2015.08.004 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 691-694. Abstract                              [Download PDF] [Read Full Text] Background Mutant C57BL/6 mouse with corneal opacity (B6-Co) appears eye open at birth […]

Promoting effect of connective tissue growth factor on expression of E-cadherin in human Tenon capsule fibroblasts

Authors: Li Jing,  Xie Anming DOI: 10.3760/cma.j.issn.2095-0160.2015.08.005 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 695-698. Abstract                              [Download PDF] [Read Full Text] Background Scarring of filtration channel following glaucoma filtering surgery is a main cause of the failure of the surgery. […]

Next generation sequencing based molecular genetic analysis of a Chinese Han family with autosomal retinitis pigmentosa

Authors: Zhou Xiaomin,  Huang Hui,  Wang Ying,  Wu Jing,  Fan Ning,  Jiang Shanming,  Liu Xuyang DOI: 10.3760/cma.j.issn.2095-0160.2015.08.006 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 699-703. Abstract                              [Download PDF] [Read Full Text] Background Retinitis pigmeutosa (RP) is a progressive inheritance disease. […]

Promoting effect of curcumin on induced differentiation of human embryonic stem cells into retinal pigment epithelial-like cells

Authors: Yin Qiuju,  Wu Yixiang,  Yu Li,  Liu Xun,  Yang Chunbo,  Li Xiaorong DOI: 10.3760/cma.j.issn.2095-0160.2015.09.002 Published 2015-09-10 Cite as Chin J Exp Ophthalmol, 2015,33(9): 774-780. Abstract                              [Download PDF] [Read Full Text] Background Pluripotent stem cell-derived retinal pigment epithelial (RPE) cells holds great […]

Feasibility of adipose tissue-derived stem cell sheet fabricated ex vivo on temperature-responsive scaffolds as seed cells for ocular surface reconstruction

Authors: Wei Qiaoling,  Xu Jianjiang DOI: 10.3760/cma.j.issn.2095-0160.2015.09.003 Published 2015-09-10 Cite as Chin J Exp Ophthalmol, 2015,33(9): 781-786. Abstract                            [Download PDF] [Read Full Text] Background Development of corneal tissue engineering creates a new therapeutic method for severe corneal diseases. However, ideal seed cells and […]

The promoting effects of ROCK inhibitor Y-27632 on the activity of limbal stem cells in corneal preservation medium

Authors: Wang Yao,  Duan Haoyun,  Yang Lingling,  Qu Mingli,  Zhou Qingjun DOI: 10.3760/cma.j.issn.2095-0160.2015.09.004 Published 2015-09-10 Cite as Chin J Exp Ophthalmol, 2015,33(9): 787-792. Abstract                              [Download PDF] [Read Full Text] Background Limbal stem cells (LSCs) play an important role on the stability of […]

Study on human adipose mesenchymal stem cells differentiating into retinal pigment epithelial-like cells and its in vivo application

Author: Guo Kai,  Luo Yan,  Li Tao,  Tian Jingyi,  Sun Wei,  Lin Shaofen,  Tang Shibo DOI: 10.3760/cma.j.issn.2095-0160.2015.09.006 Published 2015-09-10 Cite as Chin J Exp Ophthalmol, 2015,33(9): 794-797. Abstract                              [Download PDF] [Read Full Text] Background Stem cell transplantation represents a promising treatment option […]