Authors: Li Yahong, Geng Chao, Hei Kaiwen, Liu Shengnan, Wang Qi, Li Xiaorong, Zhang Yan DOI: 10.3760/cma.j.cn115989-20200119-00033 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 676-685. Abstract [View PDF] [Read Full Text] Objective To investigate the damage effect of different concentrations of N-methyl-D-aspartic acid […]
Category: Experimental Science
Bioinformatics analysis of transcriptome sequencing after the interference of extremely low frequency electromagnetic field in mouse fibroblasts
Authors: Zhu Maolin, Zhu Huang DOI: 10.3760/cma.j.cn115989-20200905-00633 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 686-692. Abstract [View PDF] [Read Full Text] Objective To analyze the changes in the transcriptome of mouse fibroblasts after exposure to extremely low frequency electromagnetic fields (ELF-EMFs) using next-generation […]
Protective effect of adeno-associated virus vector mediated heme oxygenase-1 overexpression on retinitis pigmentosa in rats
Authors: Liang Yuping, Chen Weiqi, Hong Yu, Gao Xiuyun, Guo Maosheng DOI: 10.3760/cma.j.cn115989-20201108-00754 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 693-699. Abstract [View PDF] [Read Full Text] Objective To investigate the protective effect of adeno-associated virus (AAV) vector-mediated heme oxygenase-1 (HO-1) gene overexpression […]
Relationship between BAP1, FOXO3 and ITPR2 gene expression and metastasis and prognosis of uveal melanoma
Authors: Li Yang, Feng Yu, Liu Yueming, Wei Wenbin DOI: 10.3760/cma.j.cn115989-20200714-00495 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 700-707. Abstract [View PDF] [Read Full Text] Objective To explore the potential biomarkers for the metastasis and prognosis of uveal melanoma (UM) from molecular genetics. […]
Protective effect and mechanism of cx3cr1 antibody intravitreal injection in microcirculation of retinal ischemia-reperfusion injury in mice
Authors: Li Juanjuan, Chen Chen, Li Yan, Zhang Liwei DOI: 10.3760/cma.j.cn115989-20200104-00004 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 585-592. Abstract [View PDF] [Read Full Text] Objective To investigate the protective effect of C-X3-C motif chemokine receptor 1 (cx3cr1) antibody, a microglia activation inhibitor, […]
Protective effect of asiatic acid on blood-retinal barrier in diabetic rats
Authors: Fang Mengyuan, Li Qiuming, Yang Xin, Wan Weiwei, Long Yang, Liu Hongzhuo, Wan Wencui DOI: 10.3760/cma.j.cn115989-20201024-00713 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 593-601. Abstract [View PDF] [Read Full Text] Objective To investigate the protective effect of asiatic acid (AA) on blood-retinal […]
Research on screening system of myopic maculopathy based on deep convolution neural network
Authors: Shi Chunsheng, Liu Lei, Wang Yaru, Wang Zefei DOI: 10.3760/cma.j.cn115989-20191115-00495 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 602-608. Abstract [View PDF] [Read Full Text] Objective To develop a fully automatic detection system based on the deep convolution neural network (DCNN) for screening […]
Inhibiting effect of retinal Sigma-1 receptor antagonist on the form deprivation myopia in guinea pigs and its mechanism
Authors: Chen Yuanyuan, Xie Fujuan, Li Haibo, Guan Yuxin, Mao Junfeng DOI: 10.3760/cma.j.cn115989-20200615-00433 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 477-482. Abstract [View PDF] [Read Full Text] Objective To investigate the role and mechanism of retinal Sigma-1 receptor antagonist N, N-diethyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethanaminehydrochloride (NE-100) in […]
Relationship between irradiation time of riboflavin-ultraviolet A scleral collagen cross-linking and retinal injury
Authors: Yan Dong, Liu Limei, Ming Chunxiu, Zhang Shaobin DOI: 10.3760/cma.j.cn115989-20190703-00287 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 483-489. Abstract [View PDF] [Read Full Text] Objective To investigate the effects of riboflavin-ultraviolet A scleral collagen cross-linking on the retina under different irradiation time, […]
All-trans retinoic acid-induced apoptosis signaling pathway in ARPE-19 cells
Authors: Wu Juan, Cui Dongmei, Yang Xiao, Zeng Junwen DOI: 10.3760/cma.j.cn115989-20190704-00293 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 490-497. Abstract [View PDF] [Read Full Text] Objective To investigate all-trans retinoic acid(ATRA)-induced apoptosis signaling pathway in ARPE-19 cells in vitro. Methods The APRE-19 cell […]