Authors: Chen Pengfei, Hao Yuhua, Yang Na, An Jianbin, Liu Liya, Ma Jingxue DOI: 10.3760/cma.j.issn.2095-0160.2016.06.003 Published 2016-06-10 Cite as Chin J Exp Ophthalmol, 2016,34(6): 489-495. Abstract [Download PDF] [Read Full Text] Background Choroidal neovascularization (CNV) is a common pathological basis of many ocular fundus diseases.Some treating methods […]
Category: Experimental Science
Rapid differentiation of human ESCs into RPE cells by defined xeno-free culture system
Authors: Liu Qiuhui, Wang Jing, Tian Rong, Wang Xiao, Cao Di, Lu Jing, Luo Yan DOI: 10.3760/cma.j.issn.2095-0160.2016.06.002 Published 2016-06-10 Cite as Chin J Exp Ophthalmol, 2016,34(6): 484-488. Abstract [Download PDF] [Read Full Text] Background Subretinal transplantation of retinal pigment epithelium (RPE) cells for the treatment of age-related […]
Wnt3a-induced extracellular matrix production and gel contraction in human lens epithelial cells
Authors: Bao Xiuli, Liu Tingting, Wang Yanyan, Li Lin DOI: 10.3760/cma.j.issn.2095-0160.2016.07.005 Published 2016-07-10 Cite as Chin J Exp Ophthalmol, 2016,34(7): 597-601. Abstract [Download PDF] [Read Full Text] Background Excessive production, deposition and contraction of extracellular matrix (ECM) of human lens endothelial cells (LECs) is one of […]
Inhibitory effects of bevacizumab on filtering bleb scarring following trabeculectomy in rabbits
Authors: Liang Pei, Yang Jin, Lin Jinyong DOI: 10.3760/cma.j.issn.2095-0160.2016.07.004 Published 2016-07-10 Cite as Chin J Exp Ophthalmol, 2016,34(7): 591-596. Abstract [Download PDF] [Read Full Text] Background The primary reason to trabeculectomy failure is fibrosis of conjunctiva and episclera because of progressive fibroblast proliferation and collagen deposition […]
Anti-scarring effects of triamcinolone acetonide/polylactic acid caprolactone drug-loaded electrospinning film with trabeculectomy in rabbits
Authors: Zheng Yuqiang, Wang Zhuoshi, Xu Ling, Wu Jianguo, Zhao Jun, He Wei DOI: 10.3760/cma.j.issn.2095-0160.2016.07.003 Published 2016-07-10 Cite as Chin J Exp Ophthalmol, 2016,34(7): 585-590. Abstract [Download PDF] [Read Full Text] Background Scarring of filter bleb is a main cause of failure after trabeculectomy.Administration of anti-proliferation […]
Establishment of chronic ocular hypertension rat model by transgoniscope laser photocoagulation to trabecular meshwork and its comparison with translimbal laser photocoagulation
Authors: Ma Di, Huang Chukai, Cen Lingping, Zhang Mingzhi DOI: 10.3760/cma.j.issn.2095-0160.2016.07.002 Published 2016-07-10 Cite as Chin J Exp Ophthalmol, 2016,34(7): 580-584. Abstract [Download PDF] [Read Full Text] Background The establishment of chronic ocular hypertension is a basis for the research of glaucoma.Previous laser photocoagulation method to […]
Formation of cell sheet on acellular porcine corneal stroma with human corneal endothelial cells cocultured by mouse embryonic stem cell conditioned medium
Authors: Lu Xiaoyan, Wang Zhichong DOI: 10.3760/cma.j.issn.2095-0160.2016.08.007 Published 2016-08-10 Cite as Chin J Exp Ophthalmol, 2016,34(8): 705-709. Abstract [Download PDF] [Read Full Text] Background Corneal transplantation faces a great challenge because of the shortage of corneal donors and difficulty of human corneal endothelial cells (HCECs) regeneration in […]
Inhibitory effect of curcumin, salvia miltiorrhiza and matrine on IL-1β-induced proliferation of rabbit RPE cells in vitro
Authors: Liu Liya, Ma Jingxue, An Jianbin, Liu Danyan, Gao Yanjun, Zhou Nalei, Ma Yuelei DOI: 10.3760/cma.j.issn.2095-0160.2016.08.006 Published 2016-08-10 Cite as Chin J Exp Ophthalmol, 2016,34(8): 699-704. Abstract [Download PDF] [Read Full Text] Background Proliferative vitreoretinopathy (PVR) is a common cause of vision loss clinically, and retinal […]
A study on the establishment of co-culture system of peripheral blood mononuclear cells with orbital fibroblasts and the secretion of IL-6 and IL-17A induced by phytagglutinin in thyroid associated ophthalmopathy
Authors: Pan Yuan, Xu Xueliang, Tan Jia, Xu Bei, Zhang Lingli DOI: 10.3760/cma.j.issn.2095-0160.2016.08.005 Published 2016-08-10 Cite as Chin J Exp Ophthalmol, 2016,34(8): 692-698. Abstract [Download PDF] [Read Full Text] Background The pathogenic mechanism of thyroid associated ophthalmopathy (TAO) is still unclear, which is considered to be […]
The dynamic changes of regulatory T cells in the pathogenesis of experimental autoimmune uveitis
Authors: Zhang Lian, Song Jike, Tang Kai, Zheng Fengming, Guo Junguo, Bi Hongsheng DOI: 10.3760/cma.j.issn.2095-0160.2016.08.003 Published 2016-08-10 Cite as Chin J Exp Ophthalmol, 2016,34(8): 684-690. Abstract [Download PDF] [Read Full Text] Background Studies show that regulatory T cells (Treg) are a kind of T cell subsets to […]