Category: Experimental Science

Establishment of human scleral fibroblasts-seeded collagen matrix and its mechanical properties

Authors: Hu Shoulong,  Li Li,  Cui Dongmei,  Zeng Junwen DOI: 10.3760/cma.j.issn.2095-0160.2017.02.004 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 108-113. Abstract                              [Download PDF] [Read Full Text] Background Excessive elongation of axis and expansion of sclera is one of the hot topics in the study of the pathogenesis of […]

Treatment of large irregular rabbit corneal penetrating injury with fibrin glue

Authors: Xu Li,  Li Chunyan,  Zhang Haitao,  Ma Xiumei,  Xu Xiaoyan,  Zhang Xiaoyun DOI: 10.3760/cma.j.issn.2095-0160.2017.02.002 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 102-106. Abstract                              [Download PDF] [Read Full Text] Background Suture stitching is currently the standard treatment for corneal penetrating injuries.The shortcomings of suture stitching have led to the […]

Optical performance of Toric intraocular lens rotation in Hwey-Lan Liou model eye

Authors: Zhang Bin,  Ma Jingxue,  Liu Danyan,  Cui Yuexian,  Du Yinghua,  Yang Xin DOI: 10.3760/cma.j.issn.2095-0160.2017.03.011 Published 2017-03-10 Cite as Chin J Exp Ophthalmol, 2017,35(3): 239-242. Abstract                              [Download PDF] [Read Full Text] Background The residual astigmatism following Toric intraocular lens (IOL) rotation have received much attention.However, the variation of the optical performance […]

The proliferative inhibition and apoptosis promotion of Smac on human lens epithelial cells

Authors: Kong Deqian,  Zheng Guangying,  Li Li,  Liu Yue,  Cai Fangfei DOI: 10.3760/cma.j.issn.2095-0160.2017.03.010 Published 2017-03-10 Cite as Chin J Exp Ophthalmol, 2017,35(3): 233-238. Abstract                            [Download PDF] [Read Full Text] Background Posterior capsular opacification (PCO) is a primary complication after extracapsular cataract extraction.The mechanism of PCO is associated with proliferation, migration and […]

Inhibition effects of sulforaphane-induced autophagy flux to cell proliferation on ex vivo human capsular bags

Authors: Liu Hanruo,  Yuan Bowei,  An Ying,  Wan Xiuhua DOI: 10.3760/cma.j.issn.2095-0160.2017.03.009 Published 2017-03-10 Cite as Chin J Exp Ophthalmol, 2017,35(3): 226-232. Abstract                              [Download PDF] [Read Full Text] Background Sulforaphane (SFN) is an effective chemopreventive agent and can regulate the biological molecular mechanisms to inhibit the overgrowth of cells.Autophagy is […]

Proventive effects of astaxanthin on metabolic cataract and its mechanism in type 1 diabetic rats

Authors: Yang Ming,  Wang Zhiju,  Deng Tingting,  Pan Lin DOI: 10.3760/cma.j.issn.2095-0160.2017.03.007 Published 2017-03-10 Cite as Chin J Exp Ophthalmol, 2017,35(3): 217-224. Abstract                              [Download PDF] [Read Full Text] Background The pathogenesis mechanism of diabetic cataract has not been fully elucidated.Researches showed that multiple biological pathways participate in the pathogenesis of […]

Experimental study on inhibiting graft rejection following high-risk cornea transplatation by resolvinE1 in mice

Authors: Wang Han,  Luo Dan,  Li Ting,  Zhao Min DOI: 10.3760/cma.j.issn.2095-0160.2017.03.005 Published 2017-03-10 Cite as Chin J Exp Ophthalmol, 2017,35(3): 209-215. Abstract                               [Download PDF] [Read Full Text] Background The conventional drugs for preventing and treating graft rejection have the risks of inducing adverse responses.Researches showed that resolvinE1 (RvE1) can […]

Distribution of lanosterol synthase and lanosterol in cornea, lens and retina tissue of rats

Authors: Kang Lihua,  Shen Xinyue,  Yang Mei,  Zhang Guowei,  Zhang Junfang,  Qin Bai,  Yang Ling,  Hu Nan,  Guan Huaijin DOI: 10.3760/cma.j.issn.2095-0160.2017.03.003 Published 2017-03-10 Cite as Chin J Exp Ophthalmol, 2017,35(3): 201-206. Abstract                               [Download PDF] [Read Full Text] Background Researches showed that triterpenoids, with a similar structure to lanosterol, has therapeutical effect on many systemic […]

Inflammatory mechanism and significance of tumor necrosis factor-α and interleukin-1β in pathogenesis of conjunctivochalasis

Authors: Ke Meiqing,  Zhang Xingru,  Zhou Guizhen,  Ma Yanchun,  Li Qingsong,  Xiang Minhong DOI: 10.3760/cma.j.issn.2095-0160.2017.04.009 Published 2017-04-10 Cite as Chin J Exp Ophthalmol, 2017,35(4): 325-331. Abstract                              [Download PDF] [Read Full Text] Background Conjunctivochalasis (CCh) is a common age-related ocular surface diseases.Researches showed that the inflammatory factors are upregulated in conjunctiva and […]

Expression changes of transforming growth factor-β1 and fibronectin in bovine trabecular meshwork cells cultured by iris pigment particles

Authors: Niu Chunhuan,  Wang Qiang,  Meng Jie,  Liu Yuzhen DOI: 10.3760/cma.j.issn.2095-0160.2017.04.008 Published 2017-04-10 Cite as Chin J Exp Ophthalmol, 2017,35(4): 320-324. Abstract                               [Download PDF] [Read Full Text] Background Pigmentary glaucoma and pseudoexfoliation glaucoma are characterized by pigment dispersion in trabecular meshwork, and the dipersitional pigment probably contributes to the […]