Authors: Yang Ming, Wang Zhiju, Deng Tingting, Pan Lin DOI: 10.3760/cma.j.issn.2095-0160.2017.03.007 Published 2017-03-10 Cite as Chin J Exp Ophthalmol, 2017,35(3): 217-224. Abstract [Download PDF] [Read Full Text] Background The pathogenesis mechanism of diabetic cataract has not been fully elucidated.Researches showed that multiple biological pathways participate in the pathogenesis of […]
Category: Experimental Science
Experimental study on inhibiting graft rejection following high-risk cornea transplatation by resolvinE1 in mice
Authors: Wang Han, Luo Dan, Li Ting, Zhao Min DOI: 10.3760/cma.j.issn.2095-0160.2017.03.005 Published 2017-03-10 Cite as Chin J Exp Ophthalmol, 2017,35(3): 209-215. Abstract [Download PDF] [Read Full Text] Background The conventional drugs for preventing and treating graft rejection have the risks of inducing adverse responses.Researches showed that resolvinE1 (RvE1) can […]
Distribution of lanosterol synthase and lanosterol in cornea, lens and retina tissue of rats
Authors: Kang Lihua, Shen Xinyue, Yang Mei, Zhang Guowei, Zhang Junfang, Qin Bai, Yang Ling, Hu Nan, Guan Huaijin DOI: 10.3760/cma.j.issn.2095-0160.2017.03.003 Published 2017-03-10 Cite as Chin J Exp Ophthalmol, 2017,35(3): 201-206. Abstract [Download PDF] [Read Full Text] Background Researches showed that triterpenoids, with a similar structure to lanosterol, has therapeutical effect on many systemic […]
Inflammatory mechanism and significance of tumor necrosis factor-α and interleukin-1β in pathogenesis of conjunctivochalasis
Authors: Ke Meiqing, Zhang Xingru, Zhou Guizhen, Ma Yanchun, Li Qingsong, Xiang Minhong DOI: 10.3760/cma.j.issn.2095-0160.2017.04.009 Published 2017-04-10 Cite as Chin J Exp Ophthalmol, 2017,35(4): 325-331. Abstract [Download PDF] [Read Full Text] Background Conjunctivochalasis (CCh) is a common age-related ocular surface diseases.Researches showed that the inflammatory factors are upregulated in conjunctiva and […]
Expression changes of transforming growth factor-β1 and fibronectin in bovine trabecular meshwork cells cultured by iris pigment particles
Authors: Niu Chunhuan, Wang Qiang, Meng Jie, Liu Yuzhen DOI: 10.3760/cma.j.issn.2095-0160.2017.04.008 Published 2017-04-10 Cite as Chin J Exp Ophthalmol, 2017,35(4): 320-324. Abstract [Download PDF] [Read Full Text] Background Pigmentary glaucoma and pseudoexfoliation glaucoma are characterized by pigment dispersion in trabecular meshwork, and the dipersitional pigment probably contributes to the […]
Induction of transforming growth facor-β2 to the expression of lysyl oxidases in human Tenon capsule fibroblasts in vitro
Authors: Guo Feng, Zhu Xiaoyan, Chen Xia, Zhang Yong, Tan Yan, Wu Xiaofeng, Liu Rui, Li Lei, Xian Guangjun, Xie Lin DOI: 10.3760/cma.j.issn.2095-0160.2017.04.007 Published 2017-04-10 Cite as Chin J Exp Ophthalmol, 2017,35(4): 314-319. Abstract [Download PDF] [Read Full Text] Background Researches showed that transforming growth factor-β2 (TGF-β2) promotes the activity of human Tenon capsular fibroblasts […]
Effect comparison of laser peripheral iridoplasty at different sites of iris in pigment rabbit glaucoma
Authors: Xie Maosong, Xu Guoxing, Zhou Biting, You Junmei, Huang Yihong, Chen Zhenming, Wang Jue DOI: 10.3760/cma.j.issn.2095-0160.2017.04.006 Published 2017-04-10 Cite as Chin J Exp Ophthalmol, 2017,35(4): 307-313. Abstract [Download PDF] [Read Full Text] Background Laser peripheral iridoplasty (LPI) is widely used in the treatment of glaucoma by flattening […]
Co-expression of GRP78 and Myocilin in trabecular meshwork cells of primary open angle glaucoma
Authors: Chai Fang, Ai Hua, Li Juan, Yang Xinguang DOI: 10.3760/cma.j.issn.2095-0160.2017.04.004 Published 2017-04-10 Cite as Chin J Exp Ophthalmol, 2017,35(4): 300-305. Abstract [Download PDF] [Read Full Text] Background Misfolding of Myocilin protein plays an important role in the pathogenesis of primary open angle glaucoma (POAG). GRP78 can transfer the […]
Apoptosis and autophagy of retinal ganglion cell-5 cells induced by hydrostatic pressure
Authors: Wang Yuping, Wang Jing, Yuan Yuanzhi DOI: 10.3760/cma.j.issn.2095-0160.2017.04.002 Published 2017-04-10 Cite as Chin J Exp Ophthalmol, 2017,35(4): 293-298. Abstract [Download PDF] [Read Full Text] Background Researches showed that the mitochondrial-mediated apoptosis and autophagy play an important role in the survival of retinal ganglion cells (RGCs) in glaucoma.However, […]
Excitatory toxicity of glutamate on meningothelial cells of optic nerve sheaths and its oxidative stress mechanism
Authors: Xin Xiaorong, Gong Tianxiang, Hong Ying, Dang Hong DOI: 10.3760/cma.j.issn.2095-0160.2017.05.009 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 432-437. Abstract [Download PDF] [Read Full Text] Background Meningothelial cells (MECs) occupy the predominant cell component of barrier between optic nerve and the cerebral spinal fluid, and any change […]