Category: Experimental Science

Protection effects of glutathione 2 on human lens epithelial cells against ultraviolet radiation-induced apoptosis

Authors: Guo Chenjun,  Guo Yong,  Wang Song,  Zhang Jie,  Yan Hong DOI: 10.3760/cma.j.issn.2095-0160.2018.03.003 Published 2018-03-10 Cite as Chin J Exp Ophthalmol, 2018,36(3): 169-175. Abstract                               [Download PDF] [Read Full Text] Objective To observe the damage of human lens epithelial cells (LECs) induced by ultraviolet (UV)B radiation and the expression changes of […]

Role of mitochondrial DNA in human retinal pigment epithelium cells apoptosis induced by blue light

Authors: Zhou Wenjie,  Yu Yongzhen,  Xu Zhe,  Zou Xiulan,  Li Dandan,  Zou Yuping DOI: 10.3760/cma.j.issn.2095-0160.2018.04.008 Published 2018-04-10 Cite as Chin J Exp Ophthalmol, 2018,36(4): 267-272. Abstract                              [Download PDF] [Read Full Text] Objective To research the role of mitochondrial DNA mediate the cultured human retinal pigment epithelium (hRPE) cell apoptosis induced by […]

Effects of transient receptor potential melastatin 7 on dexamethasone-mediated cytoskeletal protein remodeling of trabecular meshwork cells

Authors: Liu Liling,  Xu Jiangang,  Ouyang Zhikun,  Yang Yangfan,  Wu Kaili,  Yu Minbin DOI: 10.3760/cma.j.issn.2095-0160.2018.04.006 Published 2018-04-10 Cite as Chin J Exp Ophthalmol, 2018,36(4): 259-265. Abstract                               [Download PDF] [Read Full Text] Objective To investigate the effects of transient receptor potential melastatin (TRPM) 7 on dexamethasone (Dex)-mediated cytoskeleton remodeling in human trabecular […]

Protective effects of carnosic acid on retinal ganglion cells in acute ocular hypertension rats model

Authors:  He Liye,  Liang Liang,  Zhu Mengnan,  Xiao Changyi,  Tu Xiaokun DOI: 10.3760/cma.j.issn.2095-0160.2018.04.005 Published 2018-04-10 Cite as Chin J Exp Ophthalmol, 2018,36(4): 254-258. Abstract                               [Download PDF] [Read Full Text] Objective To observe the protective effects of carnosic acid on retinal ganglion cells (RGCs) in acute ocular hypertension rats model. Methods […]

Analysis of the serological testing results from Aier Eye Bank

Authors: Long Wenxiu,  Yang Lihong,  Xu Jie,  He Shengyu,  Li Shaowei,  Wang Congxiang,  Wang Kehua,  Ran Ruqiu,  Tang Jian DOI: 10.3760/cma.j.issn.2095-0160.2018.05.006 Published 2018-05-10 Cite as Chin J Exp Ophthalmol, 2018,36(5): 351-354. Abstract                              [Download PDF] [Read Full Text] Objective This study was to evaluate the safety of 640 corneal donors by analysing the serological testing […]

Antifungal efficacy of corneal collagen cross-linking on treating experimentally induced fungal keratitis of mice

Authors: Zhu Ziqian,  Qiu Shuanghao,  Yue Juan,  Liu Susu,  Gu Lizhe,  Zhang Hongmin,  Li Zhijie,  Wang Liya DOI: 10.3760/cma.j.issn.2095-0160.2018.05.005 Published 2018-05-10 Cite as Chin J Exp Ophthalmol, 2018,36(5): 344-350. Abstract                               [Download PDF] [Read Full Text] Objective This study was to assess the efficacy of corneal collagen cross-linking treatment on fungal keratitis. Methods Eighty […]

Morphology of intrinsically photosensitive retinal ganglion cells: distinct photoreceptors from rod/cone photoreceptors

Authors: Hu Caiping,  Xu Wenjun,  Jin Xuemin DOI: 10.3760/cma.j.issn.2095-0160.2018.05.004 Published 2018-05-10 Cite as Chin J Exp Ophthalmol, 2018,36(5): 337-343. Abstract                              [Download PDF] [Read Full Text] Objective This study was to observe the morphology of live intrinsically photosensitive retinal ganglion cells (ipRGCs) at cellular level, […]

Reactivation of visual cortical plasticity by caloric restriction mediated by AMPK-SIRT1 pathway from monocular deprivation in adult mice

Authors: Tu Yanqiong,  Luo Yulin,  Liu Zhenghai,  Wu Xiaoying DOI: 10.3760/cma.j.issn.2095-0160.2018.05.003 Published 2018-05-10 Cite as Chin J Exp Ophthalmol, 2018,36(5): 330-336. Abstract                               [Download PDF] [Read Full Text] Objective This study was to investigate the effect of caloric restriction on the plasticity of visual cortex in adult monocular deprivation (MD) […]

Protective effect of leukemia inhibitory factor on light induced retinal photoreceptors damage and its mechanisms

Authors: Dong Shuqian,  Liu Shuangzhen,  Li Qiuming DOI: 10.3760/cma.j.issn.2095-0160.2018.06.007 Published 2018-06-10 Cite as Chin J Exp Ophthalmol, 2018,36(6): 435-440. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the role of leukemia inhibitory factor (LIF) on retinal photoreceptor cells and the underlying mechanism after light damage. Methods Fifty […]

Comparison of different doses streptozotocin-induced mouse models for the research of type 1 diabetic keratopathy

Authors:  Zhang Zhenzhen,  Hu Xiaoli,  Hua Yingbin,  Zhou Qingjun DOI: 10.3760/cma.j.issn.2095-0160.2018.06.006 Published 2018-06-10 Cite as Chin J Exp Ophthalmol, 2018,36(6): 429-434. Abstract                              [Download PDF] [Read Full Text] Objective To compare the rates and pathological features of diabetic keratopathy in mice induced by single high dose […]