Authors: Liu Yinan, Shao Lei, Wei Wenbin DOI: 10.3760/cma.j.issn.2095-0160.2017.09.003 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 778-785. Abstract [Download PDF] [Read Full Text] Background Researches showed that microRNA (miRNA) is involved in the pathogenesis and development of many tumors and plays a cancer-suppressing-gene like role or […]
Category: Experimental Science
Effect of N-acetylcysteine on the transforming growth factor β1-induced transdifferentiation of retinal pigment epithelial cell to myofibroblast
Authors: Liu Shuai, Jin Haiying DOI: 10.3760/cma.j.issn.2095-0160.2017.10.008 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 894-901. Abstract [Download PDF] [Read Full Text] Background The transdifferentiation of retinal pigment epithelial (RPE) cell to myofibroblast is a central event in the development and progression of proliferative vitreoretinopathy (PVR). […]
Expression of CD147 in laser-induced rat choroidal neovascularization model
Authors: Wang Wenqiu, Lu Fengqing, Wang Hong, Sun Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2017.10.007 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 890-893. Abstract [Download PDF] [Read Full Text] Background The pathology of choroidal neovascularization (CNV) is not clear.CD147 plays a critical role in angiogenesis through activating […]
Effect of congenital stationary night blindness on oxygen induced retinal neovascularization by improved Chinese ink perfusion method
Authors: Song Meixia, Li Shang, Niu Chao, Zhang Zuoming DOI: 10.3760/cma.j.issn.2095-0160.2017.10.006 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 885-889. Abstract [Download PDF] [Read Full Text] Background Congenital stationary night blindness (CSNB) is a common genetic eye disease.Retinal angiogenesis is rarely obtained in retinal degeneration animal.The effects of CSNB […]
Effect of DNA damage marker γH2AX in the process of oxygen-induced retinal neovascularization
Authors: Li Ruolin, Chen Nan, Meng Lili, Zhu Hong DOI: 10.3760/cma.j.issn.2095-0160.2017.10.005 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 879-884. Abstract [Download PDF] [Read Full Text] Background Changes in the concentration of oxygen induced retinal neovascularization and DNA damage repair response.Overexpression of angiogenic factors is […]
Effect of Cathepsin B and vascular endothelial growth factor on the retinal neovascularization induced by hyperoxia
Authors: Wang Wenjuan, Zhou Guohong DOI: 10.3760/cma.j.issn.2095-0160.2017.10.003 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 873-877. Abstract [Download PDF] [Read Full Text] Background Vascular endothelial growth factor (VEGF) plays a key role in the vascular development and neovascularization.Studies have proved that Cathepsin B is related to […]
Promoting effects of macrogol 15 hydroxystearate micelles on corneal absorption of terbinafine hydrochloride
Authors: Zhou Tianyang, Xia Huiyun, He Jijun, Zhang Junjie DOI: 10.3760/cma.j.issn.2095-0160.2017.11.011 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 1009-1013. Abstract [Download PDF] [Read Full Text] Background Macrogol 15 hydroxystearate (HS15) is a novel soft non-ionic surfactant and is widely used to solubilize the poorly soluble drugs due […]
Optical performance of rotation and decentration of Toric intraocular lens implant in Hwey-Lan Liou model eye
Authors: Chai Qiannan, Zhang Bin, Geng Yuxin, Du Yinghua, Liu Danyan, Ma Feiyan, Wei Yuhua DOI: 10.3760/cma.j.issn.2095-0160.2017.11.010 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 1003-1008. Abstract [Download PDF] [Read Full Text] Background Cornea astigmatism can be effectively corrected by implanting Toric intraocular lens (IOL) during cataract surgery and therefore improve […]
Study on the relationship between CFTR physiological secretion pathway and intracellular calcium signaling in rabbit cornea epithelium
Authors: Lin Limian, Luo Yiling, Zhou Shiyou DOI: 10.3760/cma.j.issn.2095-0160.2017.11.009 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 998-1002. Abstract [Download PDF] [Read Full Text] Background Researches showed that cystic fibrosis transmembrane conductance regulator protein(CFTR) is a channel secreting anion and water, and it plays an important role […]
The inhibitory effects of baicalein on overexpression of proline hydroxylase 2 in hypoxia-induced retinal glial cells
Authors: Yang Ning, Lu Qiang, Yuan Mengke, Zhang Han, Cui Wei DOI: 10.3760/cma.j.issn.2095-0160.2017.11.007 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 990-996. Abstract [Download PDF] [Read Full Text] Background Proline hydroxylase 2 (PHD2) is a degrading enzyme of hypoxia-inducible factor-1α (HIF-1α) and can regulate the expression of vascular endothelial […]