Category: Review

Progress of GNAQ/GNA11 mutation in uveal melanoma

Authors: Zheng Lei,  Zhang Guoming DOI: 10.3760/cma.j.issn.2095-0160.2018.10.012 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 791-795. Abstract                               [Download PDF] [Read Full Text] Uveal melanoma (UM) is the most common primary intraocular tumor in adults, which not only affects patients’ visual function, but easily leads to death.Despite […]

Applications of CRISPR/Cas9 genome editing technology in gene therapy for hereditary eye diseases

Authors:  Wu Shijing,  Sui Ruifang DOI: 10.3760/cma.j.issn.2095-0160.2018.11.016 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 892-896. Abstract                               [Download PDF] [Read Full Text] Clustered regulatory interspaced short palindromic repeat (CRISPR)/CRISPR associated nuclease (Cas) system is an adaptive immune system that confers resistance to exogenous virus or plasmid […]

Research progress of ocular surface reconstruction with ex vivo cultured tissue engineered cell sheet

Authors:  Wang Fuyan,  Zhou Qingjun,  Xie Lixin DOI: 10.3760/cma.j.issn.2095-0160.2018.11.015 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 887-891. Abstract                              [Download PDF] [Read Full Text] Limbal stem cells (LSCs), the source of corneal epithelial cells, play an important role in the ocular surface.In recent […]

Research progress of stem cells in corneal wound healing

Authors: Chen Hongli,  Yan Chenxi,  Fu Yao DOI: 10.3760/cma.j.issn.2095-0160.2018.11.014 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 883-886. Abstract                              [Download PDF] [Read Full Text] As the outermost part, cornea plays a critical role in protecting the eyeball and functions as main component of the dioptric media.Trauma, inflammation, […]

The visual basis of the biological clock “sees” the light: intrinsically photosensitive retinal ganglion cells

Authors: Zhang Jingxue,  Wang Ningli DOI: 10.3760/cma.j.issn.2095-0160.2018.11.013 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 879-882. Abstract                              [Download PDF] [Read Full Text] Mammalian eyes mediate both image-forming and non-image-forming visual functions.Non-image-forming vision provides a measure of the ambient light for the purposes […]

Research progress of stem cells in the treatment of retinal degenerative diseases

Authors: Zhang Kefan,  Qu Xiuxia,  Fan Guoping DOI: 10.3760/cma.j.issn.2095-0160.2018.11.011 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 871-877. Abstract                               [Download PDF] [Read Full Text] Eyes are important human organs, and retinal degenerative diseases can cause irreversible blindness.Up to date, cell transplantation is an important method for the […]

Research progress cellular reprogramming technology and induced pluripotent stem cells for retinal diseases treatment

Authors: Fang Lyujie,  Ding Yong,  Liang Helena,  Wong Raymond Ching-Bong DOI: 10.3760/cma.j.issn.2095-0160.2018.11.009 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 864-869. Abstract                              [Download PDF] [Read Full Text] Current advances in cellular reprogramming technology has demonstrated that the identity of a cell can be converted […]

Advance in biomarkers of neuromyelitis optica

Authors: Chen Jun,  He Jianfeng,  Zhan Jialin  DOI: 10.3760/cma.j.issn.2095-0160.2018.12.016 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 973-976. Abstract                               [Download PDF] [Read Full Text] Neuromyelitis optica (NMO) is an autoimmune, demyelinating disease of the central nervous system manifesting with optic neuritis and longitudinally extensive transverse myelitis.Aquaporin-4 (AQP4)-IgG […]

Individual difference of response to antiglaucoma drugs and its influencing factors

Authors: Zhang Shiqi,  Yuan Huiping DOI: 10.3760/cma.j.issn.2095-0160.2018.12.014 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 967-970. Abstract                              [Download PDF] [Read Full Text] The application of antiglaucoma drugs is the main treatment for glaucoma, but there are differences in the response of patients […]