Experimental study progress in retinal disease immunomodulation by mesenchymal stem cells

Authors: Du Yuqin,  Chen Song
DOI: 10.3760/cma.j.issn.2095-0160.2015.09.019
Published 2015-09-10
Cite as Chin J Exp Ophthalmol, 2015,33(9): 853-856.

Abstract                              [Download PDF] [Read Full Text]

Mesenchymal stem cells (MSCs) derive mainly from the mesoderm pluripotent stem cells, with wide variety of sources, easily accessible, low immunogenicity, pluripotent, various damage repair, nutrition, and other features and functions. MSCs are widely used for clinical treatment of various diseases. In recent years, scholars deepens various physiological characteristics of MSCs, and the MSCs have been used in the treatment of retinal diseases. In this paper, the characteristics of the MSCs, such as immune markers, immunomodulatory properties, the role of nutrition and MSCs immune on diabetic retinopathy (DR), retinal degenerative diseases, choroidal neovascular (CNV), retinal ischemia-reperfusion immunomodulatory applications were reviewed.

Key words:

Mesenchymal stem cells; Immunity; Diabetic retinopathy; Choroidal neovascularization; Retinopathy

Contributor Information

Du Yuqin
Tianjin Key Laboratory of Ophthalmology and Vision Science, Tianjin Eye Institute, Tianjin Eye Hospital, Tianjin Medical University, Tianjin 300020, China
Chen Song
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Updated: March 23, 2023 — 2:09 am