Focus on the clinical application of limbal stem cells

Authors: Liu Zuguo,  Wang Guoliang,  Li Cheng

DOI: 10.3760/cma.j.issn.2095-0160.2018.11.002
Published 2018-11-10
Cite as Chin J Exp Ophthalmol, 2018,36(11): 822-825.

Abstract

Limbal stem cells (LSCs) transplantation is an effective surgical treatment to address limbal stem cells deficiency (LSCD) resulting from Stevens Johnson’s syndrome or corneal chemical burn.LSCs transplantation has been reported as the successful stem cell therapy for bodybuilding, while it still faces a number of daunting challenges.Researchers should pay more attention to substitute seed cell, novel cell carrier materials, effective expansion method, niche modification and immune rejection, so that patients with ocular surface diseases would get fullly therapeutic benefit.

Key words:

Limbal stem cells; Immunologic rejection; Niche

Contributor Information

Liu Zuguo
Eye Institute of Xiamen University, Xiang’an Hospital Affiliated to Xiamen University, Xiamen Eye Center Affiliated to Xiamen University, Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, Xiamen, 361102, China
Wang Guoliang
Li Cheng
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Updated: September 4, 2019 — 10:58 am